• Title/Summary/Keyword: Areca catechu

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Insecticidal Activity of Areca catechu Ethanol Extract against House Dust Mite (빈랑자 추출물의 집먼지 진드기에 대한 살충효과)

  • Jung, Jin Soun
    • Textile Science and Engineering
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    • v.51 no.1
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    • pp.43-49
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    • 2014
  • In this study, the insecticidal effect of the ethanol extract of Areca catechu against the house dust mite, Dermtophagoides pteronysinus, was examined. Ethanolic Areca catechu extract was directly applied at different concentrations (1.0, 0.5, 0.25, 0.125, 0.0625 mg/$40{\mu}l$) and then allowed an exposure of 24 hours. The 1.0 mg/$40{\mu}l$ and 0.5 mg/$40{\mu}l$ concentrations of Areca catechu ethanol extract produced mortality rates of 100% and 98%, respectively, against house dust mite, Dermtophagoides pteronysinus. Areca catechu ethanol extract at a concentration of 0.125 mg/$40{\mu}l$ produced a 50% insecticidal effect. These results proved the insecticidal effect of Areca catechu ethanol extract against house dust mite, Dermtophagoides pteronysinus. To check for the presence of the recognized insecticidal arecoline and monoterpene compounds in Areca catechu, gas chromatography-mass spectrometry and thermal desorption-gas chromatography/mass spectrometry were performed. As a result, arecoline and ten monoterpene compounds were identified in Areca catechu.

INHIBITORY EFFECT OF ARECA CATECHU L. ON THE GROWTH OF STREPTOCOCCUS MUTANS JC-2 (Streptococcus mutans JC--2의 생육에 미치는 빈랑의 억제효과)

  • Lee, Kwang-Hee;Nam, Yong-Ok
    • Restorative Dentistry and Endodontics
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    • v.20 no.2
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    • pp.839-842
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    • 1995
  • In its study, We investigated the effects of Areca catechu L on the growth and acid production of Streptococcus mutans JC-2 in broth system and the activity of glucosyltransferase. The results were summarized as follow; 1. The growth of Streptococcus mutans JC-2 was suppressed by adding Areca catechu L in broth system. Especially, its inhibitory effect was significant at 2,000ppm of concentration. 2. Areca catechu L decreased the acid production of Streptococcus mutans JC-2. Decrease of pH according to acid production was less in presence of Areca catechu L than in absence. 3. Areca catechu L exerted the inhibitory effect against glucosyltransferase activity form Streptococcus mutans JC-2.

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Biological activities of Solvent Fractions Isolated from Areca catechu L

  • Kim, Jun-Ho;Oh, Hae-Sook
    • Biomedical Science Letters
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    • v.16 no.4
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    • pp.271-277
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    • 2010
  • This study was conducted to investigate the biological activities of Areca catechu L. The antioxidative, fibrinolytic, thrombin inhibitory, and ${\alpha}$-glucosidase inhibitory activities of Areca catechu L extracted with hexane, $CHCl_3$, ethyl acetate, butanol, and water were measured. The water fraction showed the highest extraction yield at 3.65% (w/w). The butanol, $CHCl_3$, water, and ethyl acetate fractions showed strong antioxidative activities at 81.6%, 87.1%, 88.0%, and 89.5%, respectively. The fibrinolytic activity was strong only in the ethyl acetate fraction at 0.84 plasmin units/ml. The 100-fold dilution of the water fraction had the strongest thrombin inhibitory activity at 59.2%. The 100-fold dilution of butanol fraction displayed the strongest ${\alpha}$-glucosidase inhibitory activity at 88.6%. In conclusion, the extracts of Areca catechu L hold promise for use in the development of biofunctional foods to prevent cardiovascular diseases.

A STUDY ON THE INHIBITORY EFFECT OF ARECA CATECHU L. ON THE ACID PRODUCTION OF STREPTOCOCCUS MUTANS JC-2 AND ITS CYTOTXICITY (빈랑의 Streptococcus mutans JC-2의 산생성 억제효과와 세포독성에 대한 연구)

  • Lee, Gwang-Hee;Nam, Yong-Ok
    • Restorative Dentistry and Endodontics
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    • v.22 no.2
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    • pp.801-808
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    • 1997
  • In order to develop natural anticariogenic agents, we investigated inhibitory effects of Areca catechu L. extracts on the acid production of Streptococcus mutans JC-2 and its cytotoxicity on NIH 3T3 fibroblasts were also examined. The results are as follows : 1. Major organic acid produced by Streptococcus mutans JC-2 were lactic acid and acetic acid, and their productions were decreased by additions of Areca catechu L. extracts. 2. Areca catechu L. extracts were showed noncytotoxicity on NIH 3T3 fibroblasts.

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The Effects of Areca catechu Extracts on Tyrosinase Gene Expression in B16 Mouse Melanoma Cells (B16 마우스 흑색 종양 세포에서 빈랑(Areca catechu) 추출물이 티로시나아제 유전자에 미치는 효과)

  • Chin, Jong-Eon;Cho, Nam-Chul
    • The Korean Journal of Food And Nutrition
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    • v.20 no.2
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    • pp.240-244
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    • 2007
  • In this study, we found that the methanolic extract of Areca catechu repressed expression of the tyrosinase gene in B16 mouse melanoma cells containing a tyrosinase promoter. Extract concentrations of 100 ${\mu}$g/ml and 500 ${\mu}$g/ml exhibited tyrosinase gene expression rates of aproximately 62% and 48%, respectively, compared to the control. The fraction layers consisting of ethyl acetate, butyl alcohol, and water showed repressive effects on the tyrosinase gene. In particular, the butyl alcohol fraction highly repressed at 100 ${\mu}$g/ml and 500 ${\mu}$g/ml. In the MTT assay, the methanolic extracts exhibited very low cytotoxicities at 1 ${\mu}$g/ml, 10 ${\mu}$g/ml, and 100 ${\mu}$g/ml.

Desmutagenic Effect of Water Extract from Areca catechu L. on the Mutagenicity of N-Methyl-N-Nitro-N'-Nitrosoguanidinein in E. coli PQ37 (N-methyl-N-nitro-N'-nitrosoguanidine의 변이원성에 대한 빈랑 물 추출물의 돌연변이 억제효과)

  • Wu, Wei Jie;Ahn, Byung-Yong
    • Korean Journal of Medicinal Crop Science
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    • v.20 no.1
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    • pp.16-19
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    • 2012
  • The desmutagenic activity of the water extract of Areca catechu L. on the mutagenicity induced by aflatoxin $B_1$ ($AFB_1$), N-methyl-N-nitro-N'-nitrosoguani-dine (MNNG), mitomycin C (MMC) and 4-nitroquinoline 1-oxide (4-NQO) was studied by using the SOS Chromotest with Escherichia coli PQ37. The inhibition rates of water extract of Areca catechu L. at concentration of $100{\mu}g/assay$ were 41.0%, 47%, 46%, and 32% against $AFB_1$, MNNG, MMC and 4-NQO, respectively. The water extract of Areca catechu L. was separated into methanol soluble and methanol insoluble parts. The methanol insoluble part exhibited higher inhibition effect than the methanol soluble part against the mutagenic activities of MNNG. Step-wise fractionation of methanol insoluble part was done to obtain methanol, ethyl acetate and water fractions. Among these fractions, water fraction had the strongest inhibitory effect of 45.0% against mutagenicities of MNNG. The inhibition rates of aqueous fraction of methanol-insoluble from water extracted Areca catechu L. at concentrations of 1.61, 16.13, 161.29 and $322.58{\mu}g/mL$ were 12.0%, 24.0%, 47.5% and 62.0%, respectively. The water fraction showed the inhibitory effects with dose response against the mutagenic activity induced by MNNG.

EFFICACY AND BIOLOGICAL ACTIVITIES OF A NEW ANTI-AGING AGENT OBTAINED FROM ARECA CATECHU

  • Lee, Kun-Kook;Lee, Kwang-Sik;Kim, Jeong-Ha;Jo, Byung-Kee;Choi, Jung-Do
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.24 no.3
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    • pp.24-30
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    • 1998
  • Inhibitory effects of the new material obtained from Areca catechu seed (CC-516) according to a special process, and its applicability to the skin as a cosmetic raw material in terms of its efficacy were presented. Areca catechu extract out of 150 medicinal plants, exhibited high inhibitory effect on the porcine pancreatic elastase ($IC_{50}$ : $40.8{\mu}$g/ml). It also had an inhibitory effect on the human leukocyte elastase ($IC_{50}$ : 48.1$\mu$g/ml), hyaluronidase ($IC_{50}$ : $416{\mu}$g/ml), antioxidative activity ($IC_{50}$ : $45.4\mu$g/ml) and free radical scavenging activity ($SC_{50}$ : $10.2{\mu}$g/ml). The cream contained 3% of CC-516 improved skin hydration above 16.5%. Especially, the skin elasticity increases more than 35% and skin wrinkles decreased more than 23%. The CC-516 was designed to be utilized in cosmetology. The cream containing 3% of this product has not only protecting effect on the skin mechanical properties provided by the collagen and the elastin in the derm but also restructuring effect of scarring or aging tissue.

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The anti-inflammatory effect of Indonesian Areca catechu leaf extract in vitro and in vivo

  • Lee, Kang Pa;Sudjarwo, Giftania Wardani;Kim, Ji-Su;Dirgantara, Septrianto;Maeng, Won Jai;Hong, Heeok
    • Nutrition Research and Practice
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    • v.8 no.3
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    • pp.267-271
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    • 2014
  • BACKGROUND/OBJECTIVES: Overproduction of nitric oxide (NO) by the inducible nitric oxide synthase (iNOS) enzyme can cause inflammation. Cyclooxygenase-2 (COX-2) is also involved in the inflammatory response through regulation of nuclear factor-kappa B $NF-{\kappa}B$(). Areca catechu is one of the known fruit plants of the Palmaceae family. It has been used for a long time as a source of herbal medicine in Indonesia. In this study, we explored the effect of Indonesian Areca catechu leaf ethanol extract (ACE) in lipopolysaccharide (LPS)-induced inflammation and carrageenan-induced paw edema models. Recently, this natural extract has been in the spotlight because of its efficacy and limited or no toxic side effects. However, the mechanism underlying its anti-inflammatory effect remains to be elucidated. MATERIALS/METHODS: We measured NO production by using the Griess reagent, and determined the expression levels of inflammation-related proteins, such as iNOS, COX2, and $NF-{\kappa}B$, by western blot. To confirm the effect of ACE in vivo, we used the carrageenan-induced paw edema model. RESULTS: Compared to untreated cells, LPS-stimulated RAW 264.7 cells treated with ACE showed reduced NO generation and reduced iNOS and COX-2 expression. We found that the acute inflammatory response was significantly reduced by ACE in the carrageenan-induced paw edema model. CONCLUSION: Taken together, these results suggest that ACE can inhibit inflammation and modulate NO generation via downregulation of iNOS levels and $NF-{\kappa}B$ signaling in vitro and in vivo. ACE may have a potential medical benefit as an anti-inflammation agent.

Adsorption of Pb(II) Ions from Aqueous Solution Using Activated Carbon Prepared from Areca Catechu Shell: Kinetic, Isotherm and Thermodynamic Studies

  • Muslim, A.;Aprilia, S.;Suha, T.A.;Fitri, Z.
    • Journal of the Korean Chemical Society
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    • v.61 no.3
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    • pp.89-96
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    • 2017
  • This study proposed adsorption of Pb(II) ions from aqueous solution using activated carbon prepared from areca catechu shell (ACS AC) using Timphan Method. The effects of independent variables on adsorption kinetic and isotherm have been investigated by conducting experiments in batch mode at neutral pH. The structural characterization of adsorbent was done by FT-IR and SEM analysis. The Pb(II) adsorption was correlated very well with the pseudo second-order kinetic (PSOKM) and Langmuir isotherm models (LIM). Increasing NaOH mass for activation and adsorption temperature increased weakly all the parameters of adsorption kinetic and isotherm. The Pb(II) ions adsorption capacity of the ACS AC at 27 and $45^{\circ}C$ was 50.51 and 55.25 mg/g, respectively. Thermodynamic parameters were determined, and the results confirmed the Pb(II) ions adsorption should be endothermic and spontaneous process, and both physical and chemical adsorption should be taken place.

Screening of Anti-wrinkle Resource from Herbal Medicinal Extracts and Stability Test of Its Cosmetic Products (생약재 추출물로부터 주름 개선 소재의 발굴 및 이를 이용한 화장품의 안정성 시험)

  • Cho, Eun-Ah;Cho, Eun-Hye;Choi, Sun-Ju;Park, Keun-Hyoung;Kim, So-Young;Jeong, Yoon-Joo;Ku, Chang-Sub;Ha, Byung-Jhip;Jang, Dong-Il;Chae, Hee-Jeong
    • Korean Journal of Medicinal Crop Science
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    • v.19 no.2
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    • pp.126-135
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    • 2011
  • Various herbal medicinal extracts were examined for the development of cosmetic products with anti-oxidative and anti-wrinkle activity. First, total polyphenol contents and DPPH radical scavenging activities of herbal medicinal extracts were measured. Most herbal samples, except for DW extracts of Portulaca oleracea, Caesalpinia sappan, Taraxacum platycarpum, Carthamus tinctorius, and 70% EtOH extracts of Taraxacum platycarpum and Carthamus tinctorius, showed DPPH radical scavenging activity over 80% at a concentration of $400{\mu}g/m{\ell}$. SOD-like antioxidant activity of DW extracts of Syzygium aromaticum, DW extracts of Eriobtrya japonica and 70% EtOH extracts of Sophora japonica was measured as 40%, 35% and 80%, respectively at a dry matter concentration of $50{\mu}g/m{\ell}$. In elastase inhibition assay, DW extracts of Lycium chinense ($50{\mu}g/m{\ell}$) and 70% EtOH extracts of Areca catechu ($50{\mu}g/m{\ell}$) showed 50% and 40% of inhibition, respectively. At a concentration of $1.250{\mu}g/m{\ell}$, DW extracts of Lycium chinense and 70% EtOH extracts of Areca catechu showed 10% and 30% of collagenase inhibition, respectively. Skin and lotion samples were prepared using the two herbal extracts of high anti-wrinkle activity: Lycium chinense extract and Areca catechu extract. The storage stability of skin and lotion containing each of the selected herbal extracts was evaluated. pH and viscosity were used as stability indicators for the stability test under different storage temperatures and freeze-thaw cycle conditions. The skin and lotion containing each of DW extract of Lycium chinense and 70% EtOH extract of Areca catechu was showed high pH and viscosity stability. The skin and lotion containing DW extracts of Lycium chinense showed relatively higher stability than the skin and lotion containing 70% EtOH extract of Areca catechu, at cycle chamber and freeze-thaw conditions. In summary, these results indicated that cosmetics containing DW extract of Lycium chinense were relatively stable, and this herbal extract could be used as a stable functional cosmetic material.