• Title, Summary, Keyword: Activity Limitation

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Phosphatase Activity in Cheonho Reservoir

  • Kwag, No-Tae;Son, Jae-Hak;Lee, Jeong-Sub;Ahn, Tae-Young
    • Journal of Microbiology
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    • v.33 no.4
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    • pp.267-272
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    • 1995
  • Phosphatase activity was measured with other environmental factors in Cheonho reservoir in 1994. It ranged form 95 to 1,685 nM/1/h and was correlated significantly with chlorophyll-a. Such a close relation well matched the fact that over 90% of phosphatase activity was detected in > 3 $\mu\textrm{m}$ fraction. The phosphatase activity also correlated negatively with dissolved inorganic phosphate concentration, which implies derepression of phosphatase production by phosphate limitation. Significant correlation was analyzed between phosphatase activity and BOD, which also appeared to be closely correlated with chlorophyll-a. A great percentage of organic materials seems to be generated autochthonously by algae and extracellular enzyme even though allochthonous influence was thought to be stronger in Cheonho reservoir.

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Factors Affecting the Relationship Between Renal Renin Activity and Plasma Renin Activity -I. Experiments in the Two Kidney one Clip Goldblatt Hypertensive Rats- (신장내(腎臟內) Renin Activity와 Plasma Renin Activity에 영향(影響)을 미치는 요인(要因) -I. 실험적(實驗的)인 신성고혈압(腎性高血壓)에 있어서의 영향-)

  • Cho, Kyung-W.;Kim, Sun-H.
    • The Korean journal of physiology & pharmacology
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    • v.16 no.1
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    • pp.63-68
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    • 1982
  • The change of plasma renin activity is one of the most important parameters explaining the pathological physiology of the hypertension. The relation between renal renin activity and plasma renin activity has not well been documented since last decades. In an attempt to clarify the relationship a series of experiments have been done in rats. The following results were observed. 1) Renal renin activity of clamped kidney increased after silver clipping and the increments were maintained until four to five weeks of operation. 2) Renal renin activity of the untouched contralateral kidney was vulnerable to be suppressed just after clamping, and the activity disappered almost below the limitation of the radioimmunoassay sensitivity up to four weeks. 3) Plasma lenin activity was changed by the renal renin activity, but the regression coefficient from the two kidney one clip Goldblatt hypertensive rats was different from the sham-operated, or age-matched control rats. 4) Plasma renin activity of all the groups tested has the exponential curve in terms of renal renin activity. These data suggest that the renal renin activity is important to control the plasma renin activity in certain experimental condition, especially in chronic status.

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Factors Related to the Health Related Quality. of Life in Elderly Women (여성 노인의 건강관련 삶의 질에 미치는 영향 요인)

  • Sohn, Shin-Young
    • Korean Journal of Women Health Nursing
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    • v.15 no.2
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    • pp.99-107
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    • 2009
  • Purpose: This study was aimed to identify the factors related to the health related quality of life (HRQoL) in elderly women. Method: This study used data from cross-sectional surveys conducted for the 2005 National Health and Nutrition Survey, which was performed by using a face to face interview method. Data was analyzed by ANOVA, t-test, logistic regression and multiple regression using the SPSS program. Demographic characteristics, subject health state, activity limitation, K-ADL, K-IADL, EQ-5D were included in the study instruments. Result: The mean HRQoL index in the subjects was 0.68 $\pm$ 0.25. The significant predictors of the HRQoL were health status, activity limitation, activities of daily living (ADL), instrumental activities of daily living (IADL) and income. The factors accounted for 41.0% of variance in the health related quality of life of female elderly. Conclusion: These results may contribute to development of nursing strategy to improve health related quality of life. The health related quality of life program for the elderly should be planned based on results of the study.

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Influencing Factors and Trend of Suicidal Ideation in the Elderly: Using the Korea National Health and Nutrition Examination Survey(2001, 2005, 2010) (노년기 자살생각의 요인과 변화추이 분석: 국민건강영양조사 3개년도(2001, 2005, 2010)자료를 활용하여)

  • Choi, Ryoung;Hwang, Byung-Deog
    • Korean Journal of Health Education and Promotion
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    • v.31 no.5
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    • pp.45-58
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    • 2014
  • Objective: The purpose of this study was to analysis the determinants and trend of suicidal ideation the elderly in Korea. Methods: This study participants were selected the elderly over the age of 55 from the Korea National Health and Nutrition Examination Survey in 2001(n=1,122), 2005(n=2,098), and 2010(n=2,402). Statistical analysis methods used in this study were $x^2$-test, logistic regression analysis and other basic statistics such frequency, percentage using SPSS version 21.0. Results: In 2001, the influencing factors of suicidal ideation was spouses, subjective health status and stress recognition. In 2005, the influencing factors of suicidal ideation were spouses, subjective health status, chronic disease amount, activity limitation, depression experience and stress recognition. In 2010, the influencing factors of suicidal ideation were elderly, education level, subjective health status, activity limitation, depression experience and stress recognition. Conclusions: The health education considering the characteristics of each elderly group should be developed and applied to prevent adults' suicidal ideation because the factors influencing suicidal ideation were revealed differently between the elderly group.

Joint Pain in Patients with Osteoarthritis: Based on the 5th KNHNES (우리나라 골관절염 환자의 관절통증: 2012년 국민건강영양조사 자료를 이용하여)

  • Lee, Jinsook
    • Journal of muscle and joint health
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    • v.23 no.3
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    • pp.152-158
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    • 2016
  • Purpose:The purpose of this study was to examine the degree of joint pain, limitation of daily activities, and frequency of outpatient visits. Methods: This secondary analysis study used the data from the fifth Korean National Health and Nutrition Examination Survey (KNHNES). The data about general characteristics, prevalence and treatment of osteoarthritis, limitation of activities of daily living (ADL) and frequency of outpatient visits and hospitalization in 424 osteoarthritis patients over 50 years old were derived from the database. Data were analyzed with complex samples in SPSS ver. 20.0. Results: Among people with knee joint pain, 79.3% reported they had more than 4 out of 10 points of the degree of pain. Meanwhile, 97.3% of people with hip joint pain reported that they had more than 4 out of 10 points of the degree of pain. People reporting 10 out of 10 point of pain were 21.4% of those with knee joint pain and 25% of those with hip joint pain. The mean of the degree of knee joint pain was 6.35, and the mean of the degree of hip joint pain was 6.89 out of 10 points. About 50% of people with osteoarthritis visited an outpatient clinic within the last 2 weeks, and 27% had limitation of ADL. Conclusion: It is necessary to develop an integrated intervention program to improve quality of life in patients with osteoarthritis.

A Prediction on the Conservative Treatment Outcome of TMD Patients by Prognostic Factors (측두하악장애 환자의 보존적 치료결과의 예측에 관한 연구)

  • Lee, Hye-Jin;Park, June-Sang;Ko, Myung-Yun
    • Journal of Oral Medicine and Pain
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    • v.26 no.2
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    • pp.133-146
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    • 2001
  • This study was performed to predict the conservative treatment outcome of TMD patients by investigating the prognostic factors ; symptom duration, history of previous treatment, history of previous medication, history of trauma, disability of daily activity, severity of pain, noise, limitation of mouth opening(LOM) and maximum comfortable opening(MCO). Two hundreds and fifty-four subjects were selected for this study among the TMD patients who had visited the Dept. of Oral Medicine BNUH and been treated conservatively with medication, physical therapy, behavioral treatment, and splint therapy from 1991 to 2000. The subjects were divided into two groups improved or unimproved according to the treatment response following six months of conservative treatment. Those who showed less than 1 on NAS for pain, TMJ noise, and opening limitation belonged to the improved group and those who showed more than 2 on NAS belonged to the unimproved group. The two groups were compared with respect to symptom severity, number of diagnosis, history of trauma, previous treatment, previous medication, and disability of daily activity. A prognostic equation with the factors revealed to be significantly related to the prognosis of conservative treatment was obtained. The obtained results were as follows ; 1. In improved group, mean duration of history was 12 months, mean treatment duration of a patient was 4 months an mean number of treatment was about 10 times. In other words, in unimproved group, mean duration of history was 27.4 months, mean treatment duration of patient was 10.5 months and mean number of treatment was 19 times. 2. In unimproved group, multiple diagnosis, chronicity, disability of daily activity were significantly greater than that of the improved group. 3. Patients in unimproved group revealed severe noise at first visit and smaller maximum comfortable opening comparatively. 4. Prognostic factors such as duration of treatment, number of treatment, multiplicity, and chronicity and disability of daily activity showed a significant relation in prediction of improvement. 5. Prognostic equation with significant variables is as follows ; Y = 1.984 - 0.251Noise + 0.068MCO - 0.673Multiplicity. - 0.958Chronicity - 0.065Disability. Classification accuracy of 70.3 %, sensitivity of 71.4% and specificity of 66.7% were shown. 6. Prognostic equation with all factors is as follows : Y = 1.599 - 0.038Pain - 0.256Noise - 0.006Limitation + 0.068MCO - 0.580Multiplicity - 1.025Chronicity - 0.720Disability - 0.329Medication - 0.087Treatment + 0.740Trauma. Classification accuracy of 70.3 %, sensitivity of 73% and specificity of 64.3% were shown. 7. Prognostic value of the improved group with significant factors was $1.0446{\pm}1.0726$ and prognostic value of the unimproved group with significant factors was $-0.013{\pm}1.0146$. Prognostic value of the improved group with all factors was $1.0465{\pm}1.0849$ and prognostic value of the unimproved group with all factors was $-0.057{\pm}1.0611$.

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A Descriptive Study on Pain of Elderly (노인의 동통에 관한 조사연구)

  • 김주희;양경희;이현주
    • Journal of Korean Academy of Nursing
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    • v.26 no.4
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    • pp.878-888
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    • 1996
  • The main purpose of this study was getting related to the pain charactristic data of elderly. It contains past and present health status, daily living activity level, pain frequency, causes, pain area, pain intensity, pain worse causes, and pain releave causes, pain management methods. The subject were 79 elderly whose age were over 65 years old. They were lived in their home environment. Half of them were resident of middle range city at province and the others were Seoul city. The data was collected from Dec. 1st. 1995 to Jan. 30th. 1996. Interviews were held with semi-structured questionaire after pilot study by researchers. Pain measurement tool were used graphic rating scale and Abstract of Korean Pain Language Scale. To analize the subject's general characteristics, past and present health status, daily living activity level, characteristics about pain, pain management methods statistical SPSS for win frequency were employed. The findings were as follows ; 1. There were 33(41.8%) male and 46(58.2%) female Below 69 year old were 20(25.3%), 70-79 year old were 42(53.2%), over 80 year old were 17(21.5%), mean age was 74(from 65 to 89). 2. Buddhist were 24(30.4%), Christian were 29(36. 7%), the other religious status or non religians were 26 (32.9%). 3. Past good health status were 63(79.7%), not so good status were 6(7.6%). Present good health status were 19(24.1%), moderated health status were 6(7.6%), not so good status were 14(17.7%). 4. Daily living activity limitation were 39(49.4%), nonlimitation of activity were 5(6.3%). 5. Walking limitation were 3(3.8%), nonlimitation walking were 52(65,8%). 6. Insomnia was 23(29.1%), no difficult were 38(48.1%). 7. Chronic pain complaints were 64(81%), diseases causes of pain were 25(31.6%), bad health behavior causes of pain were 27(34.2%). 8. Most pain area were back 30(29.4%), leg 17(16.7%), knee 16(15.7%), arm 13(12.7%), teeth, chest and head were each 5(4.9%), loin, trunk were each 4(3.9%), the other areas were 3(3%). 9. Pain intensity was 3.49(mean) by Korean Language Scale, 6.59(mean) by graphic rating scale. Sensitive pain was 3.5(47.9%), affective pain was 3(20.8%) It was high pain level and sensitive pain. 10. Most pain worse causes moving was 35(44.3%), pain relieving causes rest was 29(36.7%), 11. Pain management method were medication 40(42.1%), physiotherapy 23(24.2%), hospital 12(12.6%), the others 7(7.4%), none 13(13.7%). The conclusion ; Present health status of eldery was not so good. Almost half of them have some diseases. Most common diseases of eldery were arthristis, respitatory and heart problems. Foully nine percent of elderly had limitation of daily living activities. Eighty one percent of eldely had chronic pain. Most of them was back pain (30%). Pain intensity was high(score over 3.5). The worsening pain causes was moving and releiving causes was rest. Pain management method were pain medication, physiotherapy. Therefore, Nursing care plan for the elderly have to focus on pain because majority of elderly have chronic high level of pain related to the arthritis.

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The Impact of Technology Innovation Activity on Managerial Efficiency: An Inverted U shaped Model (기술혁신활동이 경영효율성에 미치는 영향 : Inverted U Shaped 모형)

  • Ha, Gui Ryong;Choi, Suk Bong
    • Journal of the Korean Society for Quality Management
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    • v.46 no.3
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    • pp.551-568
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    • 2018
  • Purpose: This study addressed the relationship between technological innovation activity and management efficiency of Korean automobile firms. We tested the hypothesis of non-liner relationship of innovation activity in relation to management efficiency. Methods: We discussed prior literature in the firm innovation strategy and management efficiency studies to provide better understanding of relationships between technological innovation activity and management efficiency. As a result, we developed develop and tested a model (Inverted-U shaped) capturing the non-linear impact of technological innovation activity. While we used R&D expenditure and patent registration data for measuring firms' innovation activity, management efficiency was evaluated by using DEA(Data Envelopment Analysis). Results: Main findings of our empirical analysis indicated that the relationships between technological innovation activity and management efficiency was inverted U shaped. This implied that the relationship between technological innovation and management efficiency is inverted U-shaped non-linear, with management efficiency increasing up to a point, beyond which higher levels of R&D and patent registration activities led to a decrease in management efficiency. Conclusion: This study empirically assessed the inconclusive findings of previous research in the area of effects of innovation activities in relation to firm performance. The paper also provided theoretical and practical implications for firms who explore efficient strategy to promote the management performance through technological innovation activities. Future research directions with the limitation of the study was discussed.

Prediction of Continuous Reactors Performance Based on Batch Reactor Deactivation Kinetics Data of Immobilized Lipase

  • Murty, V.Ramachandra;Bhat, Jayadev;Muniswaran, P.K.A.
    • Biotechnology and Bioprocess Engineering:BBE
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    • v.7 no.4
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    • pp.225-230
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    • 2002
  • Experiments on deactivation kinetics of immobilized lipase enzyme from Candida cyl-indracea were performed in stirred bath reactor using rice bran oil as the substrate and temperature as the deactivation parameter. The data were fitted In first order deactivation model. The effect of temperature on deactivation rate was represented by Arrhenius equation. Theoretical equations were developed based on pseudo-steady state approximation and Michaelis -Menten rate expression to predict the time course of conversion due to enzyme deactivation and apparent half-life of the immobilized enzyme activity in PFR and CSTH under constant feed rate polity for no diffusion limitation and diffusion limitation of first order. Stability of enzyme in these continuous reactors was predicted and factors affecting the stability were analyzed.

Nitrogen Control in Corynebacterium glutamicum: Proteins, Mechanisms, Signals

  • Burkovski, Burkovski;Andreas, Andreas
    • Journal of Microbiology and Biotechnology
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    • v.17 no.2
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    • pp.187-194
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    • 2007
  • In order to utilize different nitrogen sources and to survive in a situation of nitrogen limitation, microorganisms have developed sophisticated mechanisms to adapt their metabolism to a changing nitrogen supply. In this communication, the recent knowledge of nitrogen regulation in the amino acid producer Corynebacterium glutamicum is summarized. The core adaptations of C. glutamicum to nitrogen limitation on the level of transcription are controlled by the global regulator AmtR. Further components of the signal pathway are GlnK, a $P_{II}-type$ signal transduction protein, and GlnD. Mechanisms involved in nitrogen control in C. glutamicum regulating gene expression and protein activity are repression of transcription, protein-complex formation, protein modification by adenylylation, change of intracellular localization, and proteolysis.