For continuous and successful innovation, changes in innovation system are required and have been magnified as a new controversy. With high public interest in changes of innovation system, Transition theory and policy in Netherlands are now attracting attentions of many researchers and policymakers. Transition policy in Netherlands is distinguished from existing policies for fundamental system change in that take remarkably different views and methods. Typical examples of transition in Netherlands are such as sustainable energy transition, biodiversity and natural resource transition, sustainable agriculture transition, and sustainable transportation. Transitions in Netherlands are still in the early stage of it but several positive effects are witnessing. However some problems - linking theory and practice, ambiguity of transition concept, linking long-term vision and short-term, resistance of existing regime, implementation problem, diffusion of support, etc.- to be tackled are still remaining. In spite of those problems, many lessons can be drawn from them. To guide structural changes in innovation system into the right path and cope with lock-in problem by existing system and regime, we need to learn from Transition theory and policy in Netherlands.