• Title, Summary, Keyword: 장기무게

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Development of the Reference Korean Female Voxel Phantom (한국인 기준여성 체적소형 모의체 개발)

  • Ham, Bo-Kyoung;Cho, Kun-Woo;Yeom, Yoen-Soo;Jeong, Jong-Hwi;Kim, Chan-Hyeong;Han, Min-Cheol
    • Journal of Radiation Protection and Research
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    • v.37 no.1
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    • pp.41-49
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    • 2012
  • The objective of this study is for development of the reference Korean female phantom, HDRK-Woman. The phantom was constructed by adjusting a Korean woman voxel phantom to the Reference Korean data. The Korean woman phantom had been developed based on the high-resolution color slice images obtained from an adult Korean female cadaver. There were a total of 39 organs including the 27 organs specified in ICRP 103 for effective dose calculation. The voxel resolution of the phantom was $1.976{\times}1.976{\times}2.0619\;mm^3$ and the voxel array size is $261{\times}109{\times}825$ in the x, y and z directions. Then, the voxel resolution was changed to $2.0351{\times}2.0351{\times}2.0747\;mm^3$ for adjustment of the height and total bone mass of the phantom to the Reference Korean data. Finally, the internal organs and tissue were adjusted using in-house software program developed for 3D volume adjustment of the organs and tissue. The effective dose values of HDRK phantoms were calculated for broad parallel photon beams using MCNPX Monte Carlo code and compared with those of ICRP phantoms.

STUDIES ON THE SAFETY OF KOREAN GINSENG INGESTED AS FOOD SUBSTANCE (고려인삼의 식품안전성 연구)

  • Hong Soon Keun;Lee Song Jae;Kim Young Soo;Jeon Byeong Seon;Lim Chang Hyung
    • Proceedings of the Ginseng society Conference
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    • pp.199-213
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    • 1984
  • 홍삼 분말을 혼합하여 제조한 사료로 $60{\~}80g$ 의 Sprague Dawley Rat(female) 12마리를 1군으로 하여 $1{\~}6$개월간 사육하였다. 사육기간동안. 체중증가, 혈청의 생화학적 분석, 장기(심장 폐, 신장, 간. 비장, 뇌)의 무게차 이들 장기의 병리조직검사를 하였다. 인삼 사육관과 대조군의 성장율, 장기 무게와 혈구수는 통계적 유의성은 없었으나 혈청중의 triglyce-ride, total cholesterol, free cholesterol 함량은 대조군과 유사하였고 total lipid, free fatty acid는 대조군에 비해 약간씩 감소하였다. 그러나 실험군의 total protein, phospholipid, HDL-cholesterol은 대조군에 비해 증가하였다. 실험군의 병리조직검사에서도 대조군과 차이가 없었으나, 특히 대조군의 비장에서는 조혈기능을 지닌 거핵구세포가 다수 출현하였으며 인삼 투여기간과 용량에는 비례하지 않았다. $F_{1},\;F_{2}$세대의 적혈구, 백혈구, 장기 무게와 병리조직검사는 대조군과 유사하였으며 외형적 기형도 발견되지 않았다. 이상의 결과들로 고려인삼은 건강식품으로도 매우 안전하며 조혈기능도 촉진시킴을 시사해 준다.

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A Preliminary Study on the Medication Management System of the Patients Requiring a Long-term using Textile Proximity Sensor (섬유근접센서를 이용한 장기투약자의 복약 관리 시스템 기초 연구)

  • Im, Do Hwi;Ho, JongGab;Yoo, Su Han;Lee, Yoo Jung;Min, Se Dong
    • Proceedings of the Korea Information Processing Society Conference
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    • pp.883-886
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    • 2016
  • 본 논문에서는 장기투약자의 복약 관리 시스템 개발의 기초 연구로 Textile proximity pressure sensor를 개발하였고, 약통의 무게 감지를 통하여 약의 복용 여부를 판별하는 연구를 수행하였다. 실험은 총 2가지로, 약의 개수에 따른 baseline검출 실험과 약 한알의 무게 도출 실험을 수행하였다. 잡음을 제거하기 위해 5 point의 이동평균필터(MAF: Moving average filter)를 적용하였다. 본 논문을 통해 얻은 결과는 차후 장기 투약이 필요한 환자로 하여금 규칙적으로 약을 복용하도록 하여 만성질환의 완치율을 높이는 데 기여할 수 있을 것으로 판단된다.

Effect of Dietary Organic Acid Mixture on Growth Performance, Organ Weight, Blood Immunological Parameter and Intestinal Villi Morphology in Broilers (유기산 복합물 급여가 육계 생산성, 장기무게, 혈액내 면역적 성상 및 장내 융모 형태에 미치는 영향)

  • Jang, H.D.;Yoo, J.S.;Kim, H.J.;Shin, S.O.;Hwang, Y.;Zhou, T.X.;Chen, Y.J.;Cho, J.H.;Kim, I.H.
    • Korean Journal of Poultry Science
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    • v.35 no.1
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    • pp.57-62
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    • 2008
  • The study was conducted to evaluate the effects of dietary organic acid mixture(lactic acid 12%, formic acid 9%, citric acid 5%, butyric acid 5% and phosphoric acid 6%) on growth performance, organ weight, blood immunological parameter and intestinal villi morphology in broilers. Dietary treatments included 1) CON (basal diet), 2) OA1 (basal diet + 0.1% organic acid mixture) and 3) OA2 (basal diet + 0.2% organic acid mixture). Four hundred eighty hatched Arbor Acre broiler chickens were housed in 24 pens of 20 birds each. Eight replicate pens were allotted into each treatment by completely randomized design. Daily weight gain, feed intake and feed/gain were not significantly different among the treatments. In organ weight, that of gizzard was significantly heavier in OA2 than CON (Linear effect = 0.034). However, those of spleen and intestine were not significantly different among the treatments. Blood immunological parameters such as RBC, WBC and lymphocyte were not significantly difference. In intestinal villi morphology, villi length was increased in OA1 compared to CON (Quadratic effect = 0.050). In conclusion, 0.2% organic acid mixture was effective to improve gizzard weight of broilers.

Effect of Adrenal Hormones and Diets on Diabetic Rats (부신홀몬과 식이가 당뇨병 백서에 미치는 영향)

  • 주진순
    • Journal of Nutrition and Health
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    • v.22 no.2
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    • pp.63-69
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    • 1989
  • For assessment of the effects of adrenal hormones and diets on diabetic condition, adrenalectomized. Sprague-Dawley rats were fed either high carbohydrate diet, high protein diet, or high fat diet with administration of aldosterone or corticsterone. Adrenalectomy of the rats reduced serum glucos, insulin, total cholesterol, and body weight in all types of diet feeding. In comparison with adrenalectomized control group, corticoste5rone-administered group showed significant increase of serum glucose when fed high fat diet or high protein diet ; however, aldosterone-administered group with high fat diet or high protein diet ; however, aldosterone-administered group with high hat diet showed significant decrease o serum glucose. Serum lipid was increased significantly in cortricosterone-administered group with feeding of high fat or high protein diet. There was no significant effects of aldosterone administeration on parameters determined in this study.

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Organ Weights and Splenocytic Apoptosis in γ-irradiated Korean Dark-Striped Field Mice, Apodemus Agrarius Coreae (방사선 조사된 국내 야생 등줄쥐 (Apodemus agrarius coreae) 장기무게 및 비장세포 세포고사)

  • Joo, Hyunjin;Choi, Hoon;Yang, Kwang-hee;Keum, Dong-kwon;Kim, Hee sun
    • Journal of Radiation Protection and Research
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    • v.40 no.3
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    • pp.168-173
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    • 2015
  • The present investigation was planned to estimate potential possibility of striped field mice, Apodemus agrarius coreae (A. a. coreae), as a biological dosimeter in radio-environmental ecology. We bred captured wild A. a. coreae at laboratory and classified taxonomically based on external, cranial and tooth characters. Organ weights and splenocytic apoptosis were observed in order to establish a basic data on radiation biology of A. a. coreae (male, 40 weeks old). The biological effects was observed at 24hrs following irradiation (doses : 0, 0.5, 1, 2 Gy, dose rate : $0.8Gymin^{-1}$, $^{137}Cs$). Only thymus weights was significantly decreased. Splenocytic apoptosis was increased after irradiation. But splenocytic apoptosis was decreased in 0.5 Gy ${\gamma}$-irradiated mice compared to those of 0, 1, 2 Gy (P < 0.05). These data suggested that events in thymus and spleen of Korean dark-striped field mice, A. a. coreae THOMAS, could be a potential radio-biological indicator in human environments.

Developing a Smart Pillbox to Improve the Medication Adherence of the Patients Requiring a Long-term administration (장기 투약대상자의 약물순응도를 높이기 위한 스마트 약상자의 구현)

  • Kim, Beom-Joon
    • The Journal of the Korea institute of electronic communication sciences
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    • v.8 no.4
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    • pp.611-617
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    • 2013
  • Although tuberculosis can be recovered if patients take medicine consistently, Korea shows significantly high rate in terms of incident rate and death rate of the tuberculosis patients. Considering such a situation, this paper has developed a smart pillbox that facilitates for patients requiring a long-term administration to take medicine in a regular and consistent manner. The developed smart pillbox is equipped with a load cell that can measure the weight in unit of 0.1g so that it can determine whether or not the medicine is dispensed out of itself. In addition, a software has been developed to determine the status of patient's taking medicine based on the measurement result.

Effect of Dietary Cadmium Levels on Cadmium Accumulation in Feeding Mice (식이내(食餌內) Cadmium 수준차이(水準差異)에 따른 생쥐 체내(體內)에서의 Cadmium 축적(蓄積)에 관(關)한 연구(硏究))

  • Kim, Seong-Jo;Baek, Seung-Hwa;Kook, Joong-Hwa
    • Korean Journal of Environmental Agriculture
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    • v.10 no.1
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    • pp.77-83
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    • 1991
  • An animal experiment was performed to investigate the effects of dietary cadmium on growth rates and cadmium accumulations in internal organic tissues and blood by feeding mice with dietary $cdcl_2$ additives and/or brown rice with high cadmium content as during a 12-week feeding period. The results were as follows : Mice weights decreased with increasing levels of dietary cadmium at the end of a 9-week feeding period. The weights of mice organs in the cadmium-free feeding group were higher than in the cadmium-added groups, and the weights of mice organs did not show any significant differences among feeding groups with different levels of dietary cadmium. The concentrations of cadmium in kidney and liver were much higher than in other internal organs and blood, and the next higher concentration was in the heart. The cadmium accumulation in all internal organs and blood increased with increasing dietary cadmium levels, respectively. The ratios of cadmium accumulation in organ tissues and total blood of cadmium-added groups increased with decreasing dietary cadmium levels.

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Effects of Silicone Fluids on Insulation Properties of Silicone Rubber (Silicone Fluid들이 실리콘 고무의 절연특성에 미치는 영향(1))

  • Kang, Dong-Pil;Park, Hoy-Yul;Ahn, Myeong-Sang;Kim, Dae-Whan;Lee, Hoo-Bum;Oh, Se-Ho
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • pp.40-43
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    • 2003
  • 전기방전에 대한 shed 재료의 열화내성과 우수한 발수성의 장기간 유지특성은 폴리머 애자의 장기성능에 있어서 가장 중요한 인자들이다. 애자 제조시 무결점 성형성 또한 중요한데 열화내성을 확보하기 위해 다량의 ATH의 첨가가 수반되기 때문에 적절한 process oil의 사용이 불가피하다. 사용하는 오일의 종류와 량에 따라 옥외절연물의 장기성능에 영향을 주는 표면발수성이나 방전내성은 크게 차이가 나는 것으로 밝혀지고 있다. 본 논문에서는 화학적 구조와 정도가 다른 몇 가지 실리콘 fluid들을 실리콘 고무에 처방하여 기본물성과 초고압 옥외절연물의 shed 재료로서 장기성능에 영향을 주는 방전열화내성과 표면발수성의 회복특성을 평가하였다. 실리콘 고무의 무결점 사출성형에 가소도가 중요한데 동일한 무기물 첨가조건에서 유사한 가소도를 갖게 하는데 필요한 량은 fluid들의 종류에 따라서 상당한 차이가 있었다. 특히 PDMS는 점도는 낮지만 분자량이 커서 많은 량이 첨가되어 기계적 특성저하가 크게 일어났다. 코로나 처리후 발수성 회복특성은 fluid들의 분자크기와 반응기의 종류에 따라 상당히 영향을 받았으며 분자가 클수록 초기회복속도는 다소 느려도 최종의 상시발수성은 다소 높게 유지되었으며 2일 이내에 거의 초기 접촉각으로 회복되었다. 내아크성은 무게손실이 적을수록 오차범위도 작은 안정된 특성을 보였으며 fluid들의 종류에 따른 무게손실의 차이는 크지 않았다. 트래킹 방전에 의한 무게 감소는 fluid의 분자가 크면서 페닐기를 가진 fluid들이 첨가된 고무가 우수한 특성을 보였다.

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Effect of Green Tea Beverage for the Removal of Cadmium and Lead by Animal Experiments (동물실험에 의한 녹차음료의 카드뮴 및 납 제거효과)

  • Choi, Sung-Inn;Lee, Jung-Hi;Lee, Su-Rae
    • Korean Journal of Food Science and Technology
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    • v.26 no.6
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    • pp.745-749
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    • 1994
  • Animal experiments were conducted to confirm the suppressive effect of green tea on the intestinal absorption and tissue accumulation of toxic heavy metals in rats. When drinking water contaminated with 500 and 5000 times level of water quality standard for lead or cadmium was administrated to rats for 3 weeks, feed intake and body weight gain were not significantly differrent among all groups except for high cadmium group. In the relative weights of target organs, kidney and femur showed a significant difference by heavy metal administration and green tea did not influence on the weights. Green tea showed a suppressing effect on the accumulation of heavy metals in target organs, in which the reducing effect in femur was $25{\sim}45%$ for lead, and 42% for cadmium. As calcium content of femur decreased by heavy metal administration was increased in green tea group, it was concluded that heavy metal accumulation in femur was interrupted by tea beverage.

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