• Title, Summary, Keyword: 위암환자

Search Result 512, Processing Time 0.034 seconds

Association of Nutritional Status with Clinical Outcome of Stomach Cancer Patients (위암환자의 입원초기 영양상태와 치료효과와의 관련성)

  • Kim, Young-Ok;Han, Bu
    • Journal of the Korean Society of Food Science and Nutrition
    • /
    • v.29 no.6
    • /
    • pp.1185-1189
    • /
    • 2000
  • 본 연구는 입원한 위암환자를 대상으로 영양불량의 정도를 중심으로 영양위험의 정도를 추정하며, 이러한 환자들의 초기 영양상태와 치료결과와의 관련성을 규명하기 위해 시도되었다. 연구대상은 병원에 입원한 209명의 위암환자였다. 영양불량은 표준체중백분율, 혈청알부민, 총임파구(TLC)로 판정하였으며, 치료결과는 합병증유무, 퇴원시 상태, 사망 등 세가지 관점에서 측정하였다. 표준체중백분율, 혈청 알부민, 총임파구수를 기준으로 영양상태를 보았을 때 비위험군은 39.7%였고, 위험군 I은 41.6%, 영양불량이 심한 위험군 II는 18.7%로, 환자의 60.3%가 영양상태가 불량한 것으로 나타나 위암환자 입원초기의 영양불량 정도가 심한 것으로 나타났다. 치료 결괴 퇴원시 상태가 "좋은"이 95.7%, 나쁨이 "4.3%"였으며, 사망환자는 6.8%, 합병증은 20.1%발생하였다. 또한 초기영양상태와 합병증과의 관련성은 높은 변수군 분류의 적절성(p<0.03)을 보여주고 있으며, 초기영양상태와 퇴원시의 치료상태에서도 높은 변수군 분류의 적절성(p<0.001)이 있는 것으로 나타났다. 환자의 초기 영양상태와 사망과의 관련성 검토 결과 초기영양상태가 불량한 경우 사망확률이 높은 것으로 나타나높은 상관성이 있음을 보였다. 이상의 연구결과로 볼 때 위암 환자의 초기 영양상태는 환자의 치료결과와 높은 관련성이 있는 것으로 나타났다.높은 관련성이 있는 것으로 나타났다.

  • PDF

Comparison of Stress Perception and Depression between Gastric Cancer and Gastritis Patients (위암 환자들과 위염 환자들 간의 스트레스지각 및 우울의 비교)

  • Koh, Kyung-Bong;Lee, Sang-In;Lee, Jong-Min
    • Korean Journal of Psychosomatic Medicine
    • /
    • v.2 no.1
    • /
    • pp.88-97
    • /
    • 1994
  • A comparison was made between gastric cancer and gastritis patients regarding stress Perception and depression, using Global Assessment Recent Stress(GARS) scale and Beck Depression Inventory(BDI). 50% of gastric cancer patients and 38% of gastritis patients were found to be depressed on scores of BDI scale, respectively. There was no significant difference in scores of stress perception between both the groups. However, gastric cancer patients tended to be more depressed than gastritis patients, although the difference is statistically not significant. In the gastric cancer patients, severity of psychic distress showed significantly positive correlation with depression, whereas in the gastritis patients, severity of physical symptoms showed significantly positive correlation with depression. It suggested that depression of gastric cancer patients was more likely to be related to the extent of psychic distress than that of physical symptoms. In each of both the groups, female patients showed significantly higher stress perception than male patients, and age was found to have significantly negative correlation with stress perception. In conclusion, severity of pathology of the same organ was not related to extent of stress perception and of depression in which denial of gastric cancer patients might play a role. Thus, it is emphasized that psychosocial approach is more needed for gastric cancer patients than for gastritis patients.

  • PDF

Clinical Importance of the Resection Margin Distance in Gastric Cancer Patients (위암환자에서 위절제술 시 근위부 절제연거리의 임상적 중요성)

  • Ha, Tae-Kyung;Kwon, Sung-Joon
    • Journal of Gastric Cancer
    • /
    • v.6 no.4
    • /
    • pp.277-283
    • /
    • 2006
  • Purpose: The way in which the resection margin distance for gastric cancer patients who undergo a gastric resection influences the recurrence rate, aspects of recurrence, and the prognosis according to the characteristic of the tumor is not known. We aim to find a standard for tailor-made treatment after selecting patients in this point of view who need a more sufficient resection margin. Materials and Methods: A retrospective study was done on 1,472 patients who underwent a gastrectomy due to gastric cancer at our hospital from 1992 to 2005. The median follow-up period was 37 months. Results: There were no significant differences in the recurrence rate, the aspects of recurrence, and the 5-year survival rate between early gastric cancer (EGC) patients with a resection margin distance of less than 2 cm compared with EGC patients with a resection margin distance of greater than 2 cm. However, significant differences in the survival rate were found in advanced gastric cancer (AGC) patients when the patients were classified into groups with resection margin distances less than or greater than 3 cm (P=0.02). Significant differences were noted especially in cases of diffuse histologic-type tumors located in the lower third of the stomach and in cases with Borrmann type-3 and -4 tumors. Conclusion: The distance between the tumor resection margin and the proximal gastric resection margin has no significant influence on the survival rate in EGC patients if the resection margin is negative. However, to improve a patient's survival rate, it is important to guarantee a resection margin of more than 3 cm in AGC patients, especially when the tumor is a diffuse histologic type located in the lower third of the stomach or a Borrmann type 3 and 4.

  • PDF

Do We Have to Treat Helicobacter pylori for Elderly Patients to Prevent Gastric Cancer? (고령 환자에서 위암 발병 감소를 위해 헬리코박터 제균 치료를 해야 하는가?)

  • Park, Seon-Young
    • The Korean journal of helicobacter and upper gastrointestinal research
    • /
    • v.18 no.3
    • /
    • pp.215-216
    • /
    • 2018
  • 위암의 발병률이 감소하고 있기는 하지만 전 세계적으로 여전히 연 100만 명 이상이 새롭게 위암으로 진단되고 있으며, 앞으로 향후 몇십 년 동안은 인구의 고령화로 인하여 위암에 대한 사회적 경제적 부담이 줄어들지 않을 것으로 추측된다. 최근 메타분석에서 Helicobacter pylori 제균 치료가 위암발병을 33~47% 감소시킨다고 보고하였으나, 중국에서 시행된 무작위 대조 연구에서는 제균 치료가 위암의 전구 병변 감소에 도움이 되지 않았다고 보고하고 있어 위축성 위염이나 장상피화생을 동반한 경우 제균 치료가 위암 예방에 큰 도움이 되지 않을 수 있음을 제시하고 있다. 그렇다면 위축성 위염이 있는 경우가 많은 고령 환자에서는 과연 헬리코박터 제균 치료가 도움이 될 것인가? 저자들은 빅데이터 분석을 통해 헬리코박터 제균 치료가 위암 발병에 미치는 영향을 성별과 연령에 따라 분석하였다. 2003년부터 2012년까지 'Hospital Authority'에 등록된 clarithromycin 포함 3제 요법을 받은 환자들에서의 위암 발생률과 2003년부터 2013년까지 'Hong Kong Cancer Registry'에 등록된 성별과 연령이 일치된 대조군에서의 위암기대 발생률(expected incidence)을 비교하였다. 3제 요법을 받은 73,237명의 환자들을 확인하였을 때, 평균 7.6년의 추적기간 중 200명(0.27%)에서 위암이 발생하였다. 연령에 따라 40세 미만, 40~59세, 60세 이상의 그룹으로 나누어 각각 위암발생률을 대조군과 비교한 결과 60세 이상 환자군에서만 standardized incidence ratio (SIR)가 0.82로 감소하였다. 치료 성공여부에 따라 위암 발생률을 분석하였을 때, 제균 치료에 성공한 60세 이상 군에서 SIR이 0.78로 감소하였으나 재 치료를 받은 40~59세 군에서는 SIR이 2.43으로 증가하였다. 제균 치료시점이 위암 발생률에 미치는 영향으로는 제균 치료 후 10년 미만에서의 위암 발생률에는 큰 영향이 없었으나 10년 이상 경과한 경우 60세 이상 군과 40~59세 군에서의 위암 발병률이 대조군의 위암 예측 발병률보다 낮았다.

위암환자의 진단 전 염분섭취 및 식품섭취빈도 분석

  • 정승은;조미란;김시영;조여원
    • Proceedings of the KSCN Conference
    • /
    • /
    • pp.418.2-419
    • /
    • 2004
  • 위암에 의한 사망률은 점차 감소하고 있는 추세임에도 불구하고 전체 암 발생에서 위암은 높은 비율을 차지하고 있다. 위암의 원인은 아직 정확히 밝혀지지 않고 있으나 주요 요인으로 음식 내의 첨가물, aflatoxin, nitrosamine, 인공감미료, 식용색소, BHT 등이 주목받고 있다. 또한 나트륨 함량이 높은 염장식품의 과잉섭취와 위암과 관련이 있음이 보고된 바 있다. 현재까지 위암과 연관된 식이 요인에 관한 연구는 많이 있으나 대부분이 외국에서 이루어진 것이며, 식이형태가 매우 다른 우리나라 위암환자를 대상으로 한 연구는 매우 미흡한 실정이다.(중략)

  • PDF

Preoperative and Postoperative Anemia in Patients with Gastric Cancer (위암환자의 위절제술 전후의 빈혈)

  • Sohn, Jun-Ho;Yu, Wan-Sik
    • Journal of Gastric Cancer
    • /
    • v.5 no.3
    • /
    • pp.146-151
    • /
    • 2005
  • Purpose: We have preoperatively and postoperatively investigated the characteristics of anemia in patients with gastric cancer in order to provide optimal medical care for the patients. Materials and Methods: Preoperative hemoglobin, serum iron, serum ferritin, serum vitamin $B_{12}$, and serum folic acid were measured for 321 patients with gastric cancer. These were measured again for 287 patients 6 months postoperatively. Results: Ninety-four patients (29.3%) had preoperative anemia. Preoperative hemoglobin, serum iron, and serum vitamin $B_{12}$ levels were higher in the patients with early gastric cancer than in patients with advanced gastric cancer. Preoperative hemoglobin, serum iron, and serum ferritin levels were higher in male patients than in female patients. The patients who had preoperative anemia showed a high probability of having postoperative anemia (P<0.001), and the patients who had low serum ferritin levels preoperatively showed a high probability of having low serum ferritin levels and iron deficiency anemia postoperatively (P<0.004). Conclusion: Preoperative ferritin deficiency should be improved by iron supplement, even though the patient may not be anemic at that time. Periodic postoperative measurements of the hemoglobin, serum iron, serum ferritin, serum vitamin $B_{12}$, and serum folic acid levels are highly recommended because postgastrectomy anemia is not rare. Finally, if any low hemoglobin, serum iron, serum ferritin, serum vitamin $B_{12}$, or serum folic acid levels are found, they should be treated in an appropriate way.

  • PDF

Comparision of Sodium Intakes Pattern in the Family Members of Normal and Stomach Cancer Patients (위암 환자 가족과 정상인 가족간의 Na섭취 패턴 비교)

  • Park, Chan-Kyeong;Choe, Myeon;Ju, Jin-Soon
    • Journal of the Korean Society of Food Science and Nutrition
    • /
    • v.21 no.6
    • /
    • pp.648-654
    • /
    • 1992
  • Purpose of this study was to investigate intake pattern of sodium in the family members of normal and stomach cancer patients, excluding patients themselves. Every food samples that they consumed for 3 days, drinking water, hot pepper paste, soybean paste and soy sauce from the each family were collected for Na analysis. Three days of morning urine from the each subjects was collected for determination of urinary Na excretion. Sodium contents of hot pepper paste, pickles, soups and meats in stomach cancer families were significantly higher than those in normal families. However, urinary sodium excretion between the two groups was not different. This suggests that sodium metabolism in human may be altered with a long-term intake of sodium=rich foods.

  • PDF

What is the Prognosis for Early Gastric Cancer with pN Stage 2 or 3 at the Time of Pre-operation and Operation (pN2 이상인 조기위암 환자의 수술 전과 수술 중의 평가)

  • Kim, Chan-Young;Lee, Se-Yul;Yang, Doo-Hyun
    • Journal of Gastric Cancer
    • /
    • v.6 no.2
    • /
    • pp.114-119
    • /
    • 2006
  • Purpose: The purpose of this study is to determine whether it is possible to evaluate patients with pN2 or pN3 early gastric cancer (EGC) as being in an advanced stage before and during the operation. Materials and Methods: 4,430 patients underwent a gastrectomy for cancer from 1990 to 2003. Eight of the 552 patients with EGC included pN2 or pN3. The estimated clinical and surgical stage before and during the operation were compared to the pathological results, and a follow-up of progression was done. Results: The patients were evenly distributed among all age groups with seven men and one woman. The pre-operative estimate of T1 by CT was 25% (2/8). In the main, the cT stage was over estimated. The estimate of over N2 was 50% (4/8). One patient was preoperatively staged as la sT1 during operation was 57.1% (4/7), and the estimate of over N2 was 67% (4/6). Two patients were intraoperatively evaluated as Ia. Only one patient survived over 5 years, and the mean survival of these patients was 15 months $(95%\;Cl:\;0{\sim}35.5)$. Conclusion: It was generally possible to evaluate patients with EGC of over pN2 as being in an advanced stage before and during the operation. Although very rare (2/552, 0.04%), there were EGC patients whose stages were not predictable at all. Therefore, more precise preoperative and intraoperative staging methods are warranted.

  • PDF

Informational Needs of Postoperative Gastric Cancer Patients (위암 수술 후 환자의 정보 요구)

  • Kim, Ae-Ran;Choi, Min-Gew;Noh, Jae-Hyung;Sohn, Tae-Sung;Bae, Jae-Moon;Kim, Sung
    • Journal of Gastric Cancer
    • /
    • v.9 no.3
    • /
    • pp.117-127
    • /
    • 2009
  • Purpose: Adequate health-related information provided by health professionals may help cancer patients overcome their uncertain situation and manage their healthcare. To provide information effectively, there is a need to understand the content of the patients' essential information. The purpose of this study was to identify recent informational needs of postoperative gastric cancer patients. Materials and Methods: Data were collected from 190 postoperative gastric cancer patients who attended the Stomach Cancer Patients' Day ceremony (18 November 2008) held by the Stomach Cancer Center of Samsung Medical Center with the use of a questionnaire which measured informational needs. A questionnaire with 37 items was comprised of domains of diagnostic tests, cancer therapy, prognosis, follow-up, sexual activity, stomach cancer-related information, and 7 single items. Results: The priorities of informational needs were the domains of prognosis, ways of healthcare during treatment (a single item), follow-up, stomach cancer-related information, cancer therapy, and diagnostic tests (in descending order). Items related to prognosis, diet, and management of their healthcare ranked in the top 10 informational need scores. As age decreased, the degree of informational needs about diagnostic tests, cancer therapy, sexual activity, and stomach cancer-related information increased. Conclusion: We suggest that prognosis-related information based on the accumulated institutional therapeutic outcomes and objective prognosis data should be incorporated in the current education program. Health professionals should provide comprehensible information content to cancer patients and caregivers and encourage patients to participate in their therapy with a more positive attitude.

  • PDF