• Title, Summary, Keyword: 여드름 균

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Growth Inhibition of Propionibacterium acnes by mycelial culture broth of Paecilomyces japonica in the mulberry leaf extract (뽕잎 추출물배지를 이용한 눈꽃동충하초(Paecilomyces japonica) 균사체 배양액의 여드름균(Propionibacterium acnes) 생육억제 효과)

  • Park, Sang-Sang;Sung, Suk-Hee;Ryu, Young-Bae;Cho, Yong-Un;Choi, Young-Ju;Park, Ki-Hoon;Gal, Sang-Wan
    • Journal of Mushroom
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    • v.6 no.1
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    • pp.32-37
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    • 2008
  • This study was carried out to investigate the growth inhibition of Propionibacterium acnes by mycelial culture broth of Paecilomyces japonica in the Mulberry leaf extract. The growth inhibition effect of P. japonica mycelial culture broth against P. acnes in various concentration of Mulberry leaf extract was the most effective in 3% Mulberry leaf extract. The inhibition effect of P. japonica mycelial culture broth against P. acnes according to the culture time was the moust effective after 25 days mycelial cultivation. As the treating amount of the mycelial culture broth was increased, the growth inhibition effect against P. acnes was increased gradually. The growth inhibition effect of mycelial culture broth against P. acnes according to the time of heat treatment was active by 45min at $100^{\circ}C$, while it was inactive more than 60min at $100^{\circ}C$. This result suggested that the antibacterial materials are possible to be glycoside or peptides. Taken together P. japonica mycelial culture in the Mulbarry leaf extract has a possibility to be an element of skin-care cosmetics regulating the acnes.

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Biochemical Properities, Isolation & Identification of the Propionibacterium acnes Picked from Acne Lesion (여드름병변에서 채취한 Propionibacterium acnes의 분리, 동정 및 생화학적 특성 연구)

  • Lee, Kyung-Suk;Choi, Jeung-Sook
    • Fashion & Textile Research Journal
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    • v.8 no.5
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    • pp.571-576
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    • 2006
  • Thirty P. acnes were isolated from the 30 acne patients who visited some skin care shops from Feburary of 2001 to August of 2001. They were identified by morphological features (gram stain), biochemical properties. Only P. acne strains are isolated among Propionibacteria sp. and biochemical properities of P. acnes were not different from P. acnes ATCC 11827 strain significantly. The results of the biotyping was as follow: twenty three strains of biotype I from comedone, 1 strain of biotype II from pauple, 5 strains of biotype III from pauple and pustule, and 1 strain of biotype IV from pauple were isolated respectively.

The Suppression of Inflammatory Cytokines Induced by Propionibacterium acnes Using Bacteriocin Isolated from Lactobacillus plantarum K-1 BR (Lactobacillus plantarum K-1 BR 유래 박테리오신의 여드름균에 의한 염증성 사이토카인 억제 효과)

  • Jeong, Jin Woong;Jung, Yong Hyun;Lee, Jong Sung;Yoon, Seung Won;Lee, Seung Yeon;Lee, Hong Chan;Yoon, Young Geol
    • Journal of Life Science
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    • v.26 no.8
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    • pp.970-975
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    • 2016
  • Acne vulgaris is a common chronic skin disorder that affects millions of people. The pathogenesis of acne has been known to be closely associated with the bacterium Propionibacterium acnes. Here we investigated the anti-acne activity of Lactobacillus plantarum K-1 BR by observing the expressions of proinflammatory cytokines, TNF-α, IFN-γ and IL-8, of human keratinocytes. When we applied heat-killed P. acnes to HaCaT cells, the inflammatory cytokines were induced by two- to four-fold compared to the normal control. When the bacteriocin, purified from L. plantarum K-1 BR, was pretreated to the HaCaT cells, the expression levels of TNF-α and IFN-γ stimulated by P. acnes significantly decreased to 25% and 30% of the induced levels, respectively. The IL-8 levels also significantly decreased with the concentration dependent manner of the bacteriocin. These results suggest that the bacteriocin from L. plantarum K-1 BR could reduce the expression levels of inflammatory cytokines and thus may relieve inflammations caused by acne.

Antimicrobial activity against Propionibacterium acnes bacteria of Smilacis glabrae Rhizoma extracts (토복령 추출물의 여드름 균에 대한 항균활성)

  • Park, Jang-Soon;Kwon, Hye-Jin
    • Journal of the Korea Convergence Society
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    • v.8 no.12
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    • pp.425-430
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    • 2017
  • This study was conducted to measure the antimicrobial activity and antiseptic effect of Smilax china root extracts against Propionibacterium acnes and to develop natural antimicrobial extracts as an alternative for synthetic preservatives, which have recently been controversial. Extracts were obtained from dried Korean Smilax china root at room temperature using two solvents, distilled water and 95% EeOH, separately. According to the results of this study, the antimicrobial effect of Propionibacterium acnes 3314 and Propionibacterium acnes 3320 against Propionibacterium acnes was outstanding. In particular, the clear zone of the extract using distilled water showed the highest activity with 16.61 mm. As for the result of the collection of contaminated skin sample, the clear zone was 24.48 mm. This indicates that Smilax china root extracts show a high activity against skin flora as well as a high antimicrobial activity against Propionibacterium acnes. In conclusion, it is confirmed that Smilax china root extracts can be used as raw materials for cosmetics that have antimicrobial activity and antiseptic effect, and it is expected that Smilax china root extracts will be used as basic materials for the development of future natural preservatives.

Effect of Schizandra chinensis and Pine Meddle on Growth of Pathogens Relate to Acne. (여드름 원인균의 성장에 미치는 오미자와 솔잎의 효과)

  • 성준모;박나영;이신호
    • Microbiology and Biotechnology Letters
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    • v.31 no.1
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    • pp.69-74
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    • 2003
  • Antimicrobial effect of Schizandra chinensis and pine neddle against various pathogens relate to acne (comedones). Ethanol extracts of Schizandra chinensis and pine neddle showed antimicrobial activity against Malassezia furfur Staphylococcus epidermidis and Propionibacterium acnes . The growth of M. fufur and S. epidermidis was inhibited completely by addition of 0.12% Schizandra chinensis extract to YM broth (YM) and tryptic soy broth (TSB) after 24 h incubation. The growth of Propionibacterium acnes was completely inhibited on YM and TSB containing 0.06% of ethanol extract of Schizandra chinensis and pine neddle, respectively. Minimum inhibitory concentration (MIC) of Schizandra chinensis and pine neddle against P. acnes was 0.0075% (75 $\mu\textrm{g}$/mL). The antimicrobial activities of Schizandra chinensis and pine noddle did not decrease apparantly by heat treatment at $80^{\circ}C$ for 30 min, 10$0^{\circ}C$ for 30 min and $121^{\circ}C$ for 15 min, respectively.

Killing effect of anodic eletrolyzed water on Propionibacterium acnes (양극전리수의 여드름균(Propionibacterium acnes)에 대한 살균효과)

  • Park Seul-Ki;Ryoo Kun-Kul;Lee Yoon-Bae;Lee Jong-Kwon;Lee Mi-Young
    • Proceedings of the KAIS Fall Conference
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    • pp.295-296
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    • 2005
  • 본 연구에서는 양극전리수의 여드름균에 대한 제어력을 조사해보았다.. 그 결과 대조군과 비교해보았을 때 여드름균은 양극전리수에 1 분 동안 노출되었을 때 완전히 사멸되었다.

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Efficacy of Safflower on the Acne Skin and Its Application for Facial Cleansing Biomedical Material (홍화잇꽃의 여드름피부 개선효과 및 세안용 생약식물소재 응용)

  • Park, Young-Ho;Lee, Chang-Seop
    • Journal of the Korean Chemical Society
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    • v.55 no.3
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    • pp.400-404
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    • 2011
  • Safflower is called as the 'beneficial flower' because 'it helps human health', and it was introduced as red flower in Tonguibogam due to the red color of floral leaf. From old times, it has been used for the material of cloth and rouge. Recently, polyphenol compound, the main ingredient of safflower, known as anti-aging and anti-oxidizing material in the healthy food industry becomes the emerging hot topic. This study aims to confirm by DDT (Disk Diffusion Test) assay, MTT assay, and NF-${\kappa}$B Luciferase activity inhibition assay in vitro that polyphenol compound, which is the main ingredient of safflower, has the anti-microbial efficacy to inhibit the growth of acne germs that make troubles for the teenagers or middle aged. Also it aims to evaluate its clinical efficacy on the acne skin, utilizing the facial cleansing cosmetic form of soap sample. This study can contribute to take a major step forward to the development of cosmetic soap for acne in the cosmeceutical industry.

Antimicrobial Activity of Tea Tree Oil against Pathogens relate to Acne (Tea Tree Oil의 여드름균에 대한 항균활성)

  • Seol, Jae-Won;Song, Kun-Ho;Lee, Kwang-Rae
    • Journal of Industrial Technology
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    • v.31 no.B
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    • pp.113-117
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    • 2011
  • The purpose of this study is to determine the antimicrobial effect of tea tree oil a against pathogens relate to acne. Tea tree oil extracted from Australian Melaleuca alterifolia has been studied extensively for their antimicrobial properties against different type of bacteria and fungi. Tea tree oil has been reported to have antibacterial, antiinflammatory and antitumor activities, among others. By evaluating the antibacterial effect of Tea Tree Oil of Australia, the MIC value of Tea Tree oil against P. acnes was 0.05% and 0.5% against aerobic bacteria. This study showed that Tea Tree Oil has antibacterial effect against bacteria which induce acne. Tea Tree Oil had better antibacterial effect against P. acnes compared to aerobic bacteria. It is promising to develop a nature-based functional material for makeup product, which can cure and prevent acne.

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Screening of Anti-acne Activity of Natural Products against Propionibacterium acnes (피부 여드름 치료제 개발을 위한 천연물의 항균활성 검색)

  • Sohn Ho-Yong;Kim Young-Suk;Kum Eun-Joo;Kwon Yun-Sook;Son Kun-Ho
    • Microbiology and Biotechnology Letters
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    • v.34 no.3
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    • pp.265-272
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    • 2006
  • Acne is a chronic inflammatory follicular disorder of the skin, occurring in specialized pilosebaceous units on the face, and Propionibacterium acnes, a strict anaerobic pathogen, plays an important role in the pathogenesis of acne. To develop a reliable and effective anti-acne agent, we have evaluated antibacterial activity of 500 plant extracts, prepared from 335 plants, against P. acnes. Based on the results of disc-paper method, 25 plant extracts, including the extracts of Chloranthus japonicus (aerial part), Sophora flavescens (radix), Evodia officinalis (fructus), Ginko biloba (semem), Morus alba (root bark), Aralia continentalis (whole) and Reynoutria elliptica (radix), were selected as possible sources of anti-acne agent. Among them, the extract of S. flavescens (radix) was finally selected and kuraridin and kurarinone were identified as major active compounds of S. flavescens. These results suggested that medicinal and wild plants could be the potential source of anti-acne agent.

Improvement Effect of Salicornia herbacea L. Diet on the Acne Skin (여드름 피부에 미치는 함초 식이의 피부 개선 효과)

  • Lim, Mi-Ra;Kang, Sang-Mo
    • Journal of the East Asian Society of Dietary Life
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    • v.19 no.5
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    • pp.750-760
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    • 2009
  • In this study, the various effects of Salicornia herbacea, including antioxidative function, antibiotic, and anti-inflammatory effect, and the effect of sebiparous reduction due to intervention of the DHT hormone were investigated using. The result of this study Based on this analysis, the serum total cholesterol, triglyceride, and WBC were found to be significantly decreased and SOD, Ca, K, and Zn were shown to be significantly increased significantly in the group that received the SH pill group after trial fora 12 week trials. Testosterone and DHT were increased in the SH pill group, but it was not statistically significant. In the case of the skin condition measurements, the number of blackhead pores, skin oiliness, keratin and, MIC were significantly decreased, and the pH was decreased to normal pH in the SH pill group. Therefore, it was confirmed that overall skin condition was improved due to Salicornia herbacea diet. The results of this research result can contribute so demonstrate the potential of actively using that the Salicornia herbacea can be actively developed as a health supplement, and a medication.

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