The purpose of this study was to examine the influence of human relationships, compensation, and heavy work on the burnout of childcare teachers. The subjects were 290 childcare teachers in Seoul and Gyeonggi-do province. The collected data were analyzed by t-test, one-way ANOVA, Duncan test, Pearson's correlation, and the multi regression analysis. The main findings of this study were as follows. First, there were significant differences in the burnout according to individual characteristics such as types of childcare center, daily working hours, and monthly incomes. Second, human relationships, compensation, and heavy work directly influenced the burnout of childcare teachers. A heavy workload was the most important variable in burnout of childcare teachers. Next, the relationship with directors, relationship with parents, compensation, and relationship with co-workers had an effect on burnout of childcare teachers. The results of this study provide basic data to reduce burnout of childcare teachers.