This study investigated the influence of life satisfaction, accomplishment value, peer attachment, and relationship with teachers on the self-esteem of adolescents in three time points. The study population consisted of a nationally representative sample of middle school 1st grade students who completed the Korean Children and Youth Panel Survey(KCYPS) of the National Youth Policy Institute in 2010, 2012, and 2014. Descriptive statistics used included frequency, percentage, average, and standard deviation; in addition, reliability, repeated measure ANOVA, and regression results were reported using SPSS statistics. The results were as follows. First, this study showed that the longitudinal changes of self-esteem, life satisfaction, accomplishment value, peer attachment, and relationship with teachers were significantly different across three time points. Second, longitudinal changes in adolescents' self-esteem, life satisfaction, peer attachment, and relationship with teachers differed by gender, but accomplishment value did not. Third, life satisfaction was the most influential to self-esteem and peer attachment was the second most influential in the three data sets after controlling for gender, parents' academic attainment, and residential area. The influence of life satisfaction on self-esteem decreased across the three time points, but that of peer attachment increased over time. Instruction on life satisfaction and peer attachment needs to be more highlighted in Home Economics classes to enhance the self-esteem of adolescents.