• Title, Summary, Keyword: 방사성스트론튬

Search Result 45, Processing Time 0.036 seconds

Blocking the Acute Radiostrontium Transfer from Placenta In Fetus by Soluble Chitosan in Mice (수용성카이토산에 의한 마우스태반을 통한 태아로의 방사성스트론튬 급성 전이 억제)

  • Kim, Young-Ho;Bom, Hee-Seung;Kim, Ji-Yeul
    • Journal of Radiation Protection and Research
    • /
    • v.22 no.4
    • /
    • pp.237-250
    • /
    • 1997
  • It has been reported that chitosan has little genetic toxicity as one of natural and nontoxic chelator and reduces the internal retention of radiostrontium in the mouse. This study is to examine that when water soluble chitosan is provided to the mouse on 17 days of pregnancy before and after radiostrontium contamination, how effectively it can inhibit an acute transfer of radiostrontium to fetus through placenta contaminated. Water soluble chitosan powder is mixed with general food for 60 days and 10%(Group 1) and 1%(Group 2) are provided respectively, and it is observed that the group with radiostrontium contamination on 17 days of pregnancy can inhibit more effectively the transfer of radiostrontium to fetus through placenta than control group with general food and the groups (Group 3, Group 4) with 10% and 1% of chitosan powder respectively after radiostrontium contamination (p<0.01, Table 1). It is found that when the pregnant mouse contaminated by radiostrontium on 17 days of pregnancy is prefed by chitosan, the transfer of radiostrontium to fetus through placenta can be inhibited.

  • PDF

Separation of Radiostrontium from Environmental Sample Using Strontim Selective Chromatographic Resin$(Sr.\;Spec^{TM})$ (스트론튬 선택적이온교환수지$(Sr.\;Spec^{TM})$를 이용한 환경시료중의 방사성 스트론튬의 분리)

  • Hong, Kwang-Hee;Lee, Chang-Woo;Choi, Yong-Ho;Lee, Myung-Ho
    • Journal of Radiation Protection and Research
    • /
    • v.20 no.1
    • /
    • pp.1-7
    • /
    • 1995
  • Strontium selective chromatographic material $(Sr-Spec^{TM})$ was investigated for separation of radiostrontium from environmental soil and water sample. This chromatographic material has great capacity of binding of strontium ion in nitric acid media, and has selectivity to permit the separation of stontium from bulk amount of calcium. But the extraction of strontium was reduced by the other interfering ions such as K and Ba. So, in order to apply this material to the soil sample, prior removal treatment of K and Ba was needed. But the Sr-Spec material could provides simple and effective methods for the separation and removal of radiostrontium from liquid sample.

  • PDF

The Effect of Calcium and Chitosan Metabolism to the Excretion of Radiostrontium in Mice (마우스에서 칼슘 및 Chitosan metabolism이 방사성스트론튬의 체외배출 효과에 미치는 명향)

  • Kim, Young-Ho;Bom, Hee-Seung;Kim, Ji-Yeul;Roh, Young-Bok
    • Journal of Radiation Protection and Research
    • /
    • v.22 no.1
    • /
    • pp.9-14
    • /
    • 1997
  • Chitosan, a natural nontoxic chelator, was reported to reduce whole body retention of radiostrontium in mice. As calcium has a simillar chemical properties to strontium both of which be easily bound with hydroxyapatite structure, calcium can be either a competitor or enhancer to chitosan on the removal of radiostrontium. We compared the effect of chitosan and calcium on the excretion of ingested radiostrontium ($^{85}$Sr). Chitosan or calcium($Cacl_2$) and usual food was mixed as 1:99 by weight. The mixed food to chitosan (group 1) or calcium (group 2) were given orally for 30 days before $^{85}$Sr administration. In other groups, mixed calcium and chitosan solution (group 3), 1% calcium (group 4), or 1% chitosan solution (group 5) was given for 7 days immediately after oral administration of $^{85}SrC1_2$ ($0.25{\mu}Ci$). In control group, no chitosan or calcium were given. Either chitosan or calcium was effective on the removal of $^{85}Sr$ from mouse body(Table. 1). Addition of calcium on chitosan did not improve or deteriorate the effect of chitosan on the removal of $^{85}Sr$ from mouse body. In conclusion, calcium was similarly effective on the removal of $^{85}Sr$ from mouse body.

  • PDF

A Comparison Study of Radiostrontium Chelation with Chitin, Chitosan, EDTA and DTPA (카이틴, 카이토산, EDTA, DTPA의 방사성스트론튬(Sr-85) 착화물 형성에 관한 비교 연구)

  • Bom, Hee-Seung;Kim, Young-Ho;Kim, Ji-Yeul
    • The Korean Journal of Nuclear Medicine
    • /
    • v.32 no.4
    • /
    • pp.391-395
    • /
    • 1998
  • Purpose: Chitin and chitosan are nontoxic natural chelators that chelate radiostrontium effectively. The purpose of this study was to compare radiostrontium chelation of chitin and chitosan with that of well known chemical chelators, namely EDTA and DTPA. Materials and Methods: The chelaton rates of chitin, chitosan, EDTA and DTPA were compared using a column chromatography method (Sephadex G-25M, Sweden). Three kinds of chitins and four kinds of chitosans were used. All of them were water soluble. Results: Phosphated chitosan showed the highest chelation yield of 97% at pH 7. All of chitins, chitosans, EDTA and DTPA showed chelation yield of more than 90% independent of varing pH level. Conclusion: Chitin and chitosan have similar chelation rate as compared with EDTA and DTPA.

  • PDF

Selective separation of Strontium in the solution containing Calcium by Supported Liquid Membrane (함침형 액막을 이용한 Calcium 함유 용액으로부터 Strontium의 선택적 분리)

  • Choi, Young-Woo;Moon, Seung-Hyeon;Lee, Chang-Woo
    • Journal of Radiation Protection and Research
    • /
    • v.24 no.1
    • /
    • pp.9-15
    • /
    • 1999
  • In order to separate $Sr^{2+}$ selectively from environmental sample solutions containing $Ca^{2+}$, supported liquid membranes(SLM) were prepared and their characteristics of separation were investigated. The contents of carriers, DC18C6 and DNNS, in SLM affected the permeabilities of metal ions and selectivities of $Sr^{2+}$. The selectivity of $Sr^{2+}$ reached to 93.3% in a SLM with 0.1 M DC18C6 and 25 mM DNNS. When the ratio of $Sr^{2+}$ to $Ca^{2+}$ concentration in the feed solution was in the range of 1/25 to 1/50, the selectivity of $Sr^{2+}$ was greater than 90 %. Therefore, it is considered that the SLM prepared in this study is capable of treating environmental sea-water samples for strontium measurement.

  • PDF

Analysis of Sorption and Desorption Behaviors of Radionuclides (Cobalt and Strontium) in Natural Soil (자연 토양에서의 방사성 핵종(Co, Sr)의 흡/탈착 거동 특성 평가)

  • Cheon Kyeong-Ho;Shin Won Sik;Choi Jeong-Hak;Choi Sang June
    • Proceedings of the Korean Radioactive Waste Society Conference
    • /
    • /
    • pp.485-495
    • /
    • 2005
  • This study was conducted to investigate sorption and desorption behaviors of radionuclides (Cobalt and Strontium) in natural soil. Sorption kinetics and isotherms were analyzed to predict sorption behaviors of radionuclides in natural soil and the experimental data were fitted to several sorption models. Desorption experiments were also performed with or without CMCD at constant pH and ion strength conditions. The results showed that $Sr^{2+}$ was more strongly sorbed than $Co^{2+}$ in natural soil. Both $Co^{2+}$ and $Sr^{2+}$ followed a pseudo-second order kinetics and Sips model. The desorption-resistance of $Co^{2+}$ and $Sr^{2+}$ was estimated using a natural surfactant Carboxymethyl-${\beta}$-cyclodextrin(CMCD) or non-desorbing fraction. Desorption of radionuclides was partially irreversible and $Sr^{2+}$ was more resistant than $Co^{2+}$ Addition of CMCD facilitated desorption of $Co^{2+}$ and $Sr^{2+}$ from soil.

  • PDF

Effect of Chitosan on the Elimination of Intraperitoneally Administered Radiostrontium (Sr-85) (마우스복강내 투여한 방사성스토론튬의 체외배설 촉진제로서 카이토산의 효과에 관한 연구)

  • Kim, Ji-Yeul;Kim, Kwang-Yoon;Bom, Hee-Seung;Kim, Hee-Kyung
    • The Korean Journal of Nuclear Medicine
    • /
    • v.27 no.2
    • /
    • pp.293-297
    • /
    • 1993
  • Chitosan is a natural chelating agent. It is derived from chitin which is a cellulose-like biopolymer distributed widely in nature, expecially in shellfish, insects, fungi, and yeast. The purpose of the present study is to investigate whether orally given water soluble chitosan can eliminate intraperitoneally injected radiostrontium (Sr-85) in mice. Water soluble chitosan and usual food was mixed as 10:90 by weight. The mixed food were fed for 60 (group 1) or 90 days (group 2). No chitosan was given to the control group. Each group consists of 5 mice. Sr-85 ($0.2{\mu}Ci$) was intraperitoneally injected after completion of prefeeding of usual or mixed food. The same food was given for more 5 days. The animals were sacrificed at the 6th day. Isolated spines, skulls, femurs, tibias, teeth, and tails were counted by a gamma counter. The retention of Sr-85 in bones was significantly lowere in the prefeeding groups (p<0.01). It was lowest in the 90 day prefeeding group. Therefore, prefeeding of water-soluble chitosan was effective on the removal of intraperitoneally injected radiostrontium.

  • PDF