• Title, Summary, Keyword: 방사선 조사

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The Effect of Combination of Radiation with 5-Fluorouracil on Mouse Jejunal Crypt Cells (5-Fluorouracil 투여가 마우스 공장 소낭선세포의 방사선조사 효과에 미치는 영향)

  • Huh, Seung-Jae;Park, Charn-Il
    • Radiation Oncology Journal
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    • v.3 no.2
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    • pp.87-93
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    • 1985
  • The interaction of radiation and 5-Fluorouracil (5-FU) on mouse jejunal crypt cells was studied using the microcolony survival assay. 150mg/kg of 5-FU was injected intraperitoneally 15 minutes before irradiation and 6 hours after irradiation. Jejunal crypt cells of mouse survived more when 5-FU was given 15 minutes before irradiation than giving it 6 hours after irradiation. The mean lethal doses (Do) of each of irradiation alone group, 5-FU injection group of 15 minutes preceding irradiation, and 5-FU injection group of 6 hours post irradiation were, 135, 135, and 114 rad respectively. The dose effect factor (DEF) of each of 5-FU injection groups of 15 minutes preceding irradiation and of 6 hours post irradiation were 1.13 and 1.27

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A Study on the Recognition of Radiation Irradiation Foods in Radiology College Students (방사선과 대학생들의 방사선조사식품 인식도에 관한 연구)

  • Yeo, Jin-Dong;Jeon, Byeong-Kyu
    • Journal of the Korean Society of Radiology
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    • v.12 no.5
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    • pp.603-614
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    • 2018
  • This study aims to identify the awareness of radiation irradiation foods for radiologists, to help them understand the radiation irradiation foods properly, and to provide basic data on educational programs. The survey was conducted from February 1 to 28, 2018, with a survey of university students majoring in radiology at universities in Daegu and Gyeongbuk provinces. 73.7% of the respondents said that they did not have educational experience in radiological survey foods and related educational experiences. 49.8% of radiologists and 31.6% of school education were the most effective methods of radiation survey foods. As for the intention to participate in education on radiation irradiated foods, 54.5% of the respondents said that they are "normal" and that the participation rate of the students can be increased when providing education on radiation irradiated foods. As for when it is appropriate to conduct education on radiation-invested foods, 27.7% from 'Elementary School' and 23.0% from 'Middle School' are shown. Considering the above results, it is deemed necessary to develop specific promotional activities and educational programs for the overall recognition and clear understanding of irradiated food products of college students who are sensitive to diet.

Consumers' attitude to purchase irradiated foods and analysis of factors to distinguish acceptor groups (소비자의 방사선조사 식품 수용도 및 수용집단분류에 영향을 미치는 변수 분석)

  • Kim, Hyo-Chung;Kim, Mee-Ra
    • Journal of the Korean Society of Food Culture
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    • v.14 no.4
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    • pp.289-304
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    • 1999
  • The purpose of this study was to examine the consumers' acceptance of irradiated foods according to sociodemographic characteristics and the factors to distinguish subjects with differential levels of their willingness to buy them. Data were collected from the 365 women living in Youngnam area by the self-administered questionnaire. The results from this study were as follows. First, consumers were concerned regarding food safety issues in general and particularly preservatives. Second, many subjects had not heard of the irradiated foods and showed wait-and-see attitude in the willingness to accept them. Consumers' willingness to purchase them were higher than any other cases if radiation would not remain in foods. Third, the results from the discriminant analyses showed that the concern toward food safety, perceived innovativeness, willingness to pay more for organic foods, and knowledge of irradiation were the factors to distinguish groups with differential levels of willingness to purchase the irradiated foods. The results from the study imply that accurate and scientific information about food irradiation should be given to the consumers.

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Histomorphologic Change of Radiation Pneumonitis in Rat Lungs : Captopril Reduces Rat Lung Injury Induced by Irradiation (X-선 조사로 생긴 흰쥐 폐장 상해의 형태학적 변화: Captopril에 의한 폐장 상해의 경감 효과)

  • Kim, Jin-Hee
    • Radiation Oncology Journal
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    • v.17 no.3
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    • pp.238-248
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    • 1999
  • Purpose : To assess the histomorphologic changes in the rat lung injury induced by radiation, to determine whether captopril reduces the rat lung injury and to evaluate change in TNF-${\alpha}$ and TGF-${\beta}$ in rat lung damage by radiation and captopril Methods and material : Right lungs in male Sprague-Dawley rats were divided irradiation alone (10, 20, 30 Gy) or radiation (same dose with radiation alone group) with captopril (500 mg/L). Radiation alone group were sacrificed at twelve hours and eleven weeks after radiation and radiation with captopril group (captopril group) were sacrificed at eleven weeks after radiation with captopril. We examined the light microscope and electron microscopic features in the groups. Results : In radiation alone group, there were patch parenchymal collapse and consolidation at twelve hours after radiation. The increase of radiation dose shows more prominent the severity and broader the affected areas. Eleven weeks after radiation, the severity and areas of fibrosis had increased in proportion to radiation dose given in the radiation alone group. There was notable decrease of lung fibrosis in captopril group than in radiation alone group. The number of mast cells rapidly increased with increase of radiation dose in radiation alone group and the degree of increase of mast cell number and severity of collagen accumulation more decreased in captopril group than in radiation alone group. In radiation alone group, expression of TNF-${\alpha}$ and TGF-${\beta}$ increased according to increase of radiation dose at twelve hours after radiation in both group. At eleven weeks after radiation, expression of TGF-${\beta}$ increased according to increase of radiation dose in radiation group but somewhat decreased in captopril group. In the captopril group the collagen deposition increased but less dense than those of radiation alone group. The severity of perivascular thickening, capillary change, the number and degranulation of mast cells more decreased in the captopril group than in the radiation alone group. Conclusion : It is concluded that the effect of captopril in the rat lungs after radiation was considered to be due to its effect on inhibition of mast cells and reduction of collagen deposition, and captopril may be protect in lung damage after radiation. We observed expression of TNF-${\alpha}$ and TGF-${\beta}$ increased at the early phase after radiation and expression of TGF-${\beta}$ increased in proportion to increase of radiation dose at the chronic phase after radiation. This results will contribute to future investigation in reduction mechanism of captopril in lung damage after radiation.

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Radioprotective Effects of Grifola umbellata Extracts on ${\gamma}$ - Irradiated Mice (저령(猪笭) 추출물이 감마선에 조사된 생쥐에 미치는 방사선 방호효과)

  • Yoo, Beong-Gyu;Park, Joon-Chul
    • Journal of radiological science and technology
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    • v.23 no.1
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    • pp.77-80
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    • 2000
  • 전신 ${\gamma}$-선 조사전 Grifola umbellata(Gu) 추출물의 단일 투여가 생쥐의 생존율, 체중, 기관 무게 및 혈액세포에 미치는 효과를 조사하였다 ${\gamma}$-선 조사 24시간 전에 Gu 추출물을 복강 투여하였을시, ${\gamma}$-선을 조사한 생쥐의 40-day 생존율을 65.5%에서 78.6%로 증가시켰다. Gu 추출물의 투여는 ${\gamma}$-선 조사에 의한 비장과 흉선의 무게 감소를 완전히 막아주었다(P<0.05, P<0.01) 또한 이와 유사하나 다소 적은 방사선 방호효과가 Gu 투여군의 고환에서도 관찰되었다(P<0.05). Gu 추출물의 투여는 ${\gamma}$-선 조사시 나타나는 조사 후 7일째까지의 백혈구와 림프구수의 현저한 감소를 지연시켰고, 회복속도를 촉진시켰다. 또한 21일째후의 적혈구수의 회복을 촉진시켰다. 이와 같은 결과에서 Gu 추출물의 방사선 방호효과를 알 수 있다.

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방사선 식품조사에 관하여 1 - II.세계 각나라의 방사선 식품조사 관련 연구$\cdot$개발 실태 및 우리나라 수의$\cdot$축산분야의 현황

  • 김희선;운재호
    • Journal of the korean veterinary medical association
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    • v.37 no.5
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    • pp.447-456
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    • 2001
  • 제2차세계대전 전후에 시작된 식품조사에 관한 연구-개발 노력은 이미 결실단계에 들어서, 여러나라에서 다수 품목이 실용화 단계에 접어들었다. 우리나라에서도 최근에 식품조사에 관한 이용성과 실용화에 대한 관심이 높아지고 있지만, 방사선 조사를 식품에 적용하기 위해서 해결되지 않으면 안되는 문제가 산더미처럼 쌓여있는 것이 현실이다. 전리방사선에 의해서 처리된 식품의 안전성과 잇점에 대해서는 많이 보고되고 있다. 식품 방사선 조사에 대한 최근의 흐름을 보면 방사선 조사량이 증가되고, 대상 품목도 점점 확대되고 있어서 상대적으로 안정성에 대하여 새롭게 검토하여야 할 측면이 많아지고 있다고 할 수 있다. 국제연합식료농업기구(FAO), 세계보건기구(WHO), 국제원자력기관(IAEA)가 합동으로 설립한 국제식품조사고문그룹(ICGFI)은, 1990년 이후 식품조사기술의 안전성과 적절한 이용에 대하여 더 많은 정보를 제공하고 있다. 여기에서는 ICGFI가 1993년에 발행한 책자를 기초로 하여, 세계 여러나라의 연구-개발상황과 실용화 수준, 식품조사 이용의 주요한 문제점을 설명하고자 한다. 또한, 우리나라 수의분야에서의 현황에 대하여 간단히 생각하여 보고자 한다.

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Knowledge, Attitude and Behavior of High School Students Regarding Irradiated Foods (고등학생의 방사선조사식품에 대한 지식, 태도 및 행위)

  • Choi, Yoonseok;Song, Jongnam;Jeong, Moontaek;Choi, Namgil;Han, Jaebok
    • Journal of the Korean Society of Radiology
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    • v.8 no.6
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    • pp.309-315
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    • 2014
  • This paper presents basic supporting data necessary for planning an educational intervention strategy as part of a communication strategy that would form an extensive national consensus on and enhance national understanding of irradiated foods. A survey was conducted to collect data on the knowledge, attitude, and behavior with regard to irradiated foods among high school students, on whom education has a great ripple effect compared with the general public. The results show that 82.9% (627 students) have acquired no information, whereas 89.3% (675 students) have received no education on irradiated foods. The reason for these overwhelmingly large percentages is the lack of available opportunity for education(88.2%). Their level of knowledge on irradiated foods scores 1.71 points (out of 10 points), which is very low, whereas their attitude toward the safety of irradiated foods scores 2.76 points (out of 5 points), which is relatively low as well. As such, we predict that their tendency to purchase and consume irradiated foods is low, given their very low level of knowledge of and negative attitude toward irradiated foods. The students who have been educated on irradiated foods show a higher level of positive attitude (p<0.001) toward irradiated foods compared with those who have had no education. This result suggests the need to provide high school students with knowledge on irradiated foods as well as education in the same to help them form a proper attitude toward these food items.

Inhibition of Photooxidation by Breakdown of ChlorophyII in Oil Model System Using Gamma Irradiation (감마선 조사된 유지 model system의 chlorophyII 제거 및 광산화 억제)

  • Lee, Kyong-Haeng;Jo, Cheo-Run;Yook, Hong-Sun;Byun, Myung-Woo
    • Korean Journal of Food Science and Technology
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    • v.33 no.6
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    • pp.693-699
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    • 2001
  • ChlorophyII destruction by irradiation in linoleic acid in methanol system was studied. ChlorophyII b standard (3 ppm) was added into methanol solution containing 1% of linoleic acid, and the sample was irradiated up to 20 kGy with or without nitrogen gas-bubbling. The content of chlorophyII b was analyzed by HPLC, and Hunter color value and UV-visible spectra were analyzed during 6 hr of photooxidation. The content of chlorophyll was reduced by irradiation and completely destroyed at 2.517 kGy. The model system with nitrogen gas-bubbling did not develop the lipid oxidation after irradiation or photooxidation at 20 kGy UV-visible spectra showed decreasing values of optical density by increase of irradiation doses, supporting the destruction of chlorophyII b. The results indicate that irradiation technology can be applied to reduce or eliminate the residual chlorophyII and to prolong the shelf-life of oil products.

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방사선 조사식품의 검지방법 연구

  • 정형욱;핸리델린세;권중호
    • Food Industry
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    • pp.55-71
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    • 1999
  • 방사선 식품조사기술은 마침내 세계 여러 나라에서 실용화되고 있다. 식품조사 (food irradiation)는 식품의 위생적 품질개선, 수확 후 손실감소, shelf-life의 연장 등의 목적으로 이용되고 있다. 관련 규정에 따라 방사선 조사된 식품은 안전(safe)하고 건전(wholesome)하지만, 소비자들은 방사선 조사된 식품과 조사되지 않은 식품을 자유롭게 선택할 수 있기를 바란다. 이를 위해서는 조사된 식품에서 labelling이 필수적이다. 식품조사기술에 관련된 규정의 준수를 유도하기 위하여 피조사체 식품 자체를 분석하여 조사 여부를 검지$\cdot$확인하는 것은 아주 바람직한 방법이라 할 수 있다. 최근 몇 년 사이에 방사선 조사시 야기되는 식품의 물리적, 화학적 및 생물학적 변화를 바탕으로 방사선 조사식품을 검지하는 방법에 많은 발전이 거듭되고 있으며, 이에 본 고에서는 최근의 연구동향에 대하여 소개하고자 한다.

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