This study analyzed the impact of women's self-preservation on their intention to start a business by using self-efficacy as a mediation, reflecting the importance of women's self-preservation to adapt to the new environment of start-up. In particular, in addition to the overall self-preservation, the sub-factors of behavioral delay, compensatory natural strategy, and constructive thinking strategy were also validated. As a research method, 198 people who responded to the online survey were analyzed using Model 4 of the PROCESS macro proposed by Hayes(2018), and indirect effects were analyzed by designating 5,000 bootstrapping samples. The findings were as follows. First, self-efficacy has been shown to have a mediating effect in which women's self-preservation influences their intention to start a business. At this time, the medium effect was shown as a partial medium. Second, the sense of self-efficacy was found to have a mediating effect on women's behavior-oriented strategies affecting their intention to start a business. At this time, the medium effect was shown as a partial medium. Third, self-efficacy was found to have a mediating effect in which women's natural compensatory strategies affect their intention to start a business. At this time, the medium effect was shown as a partial medium. Fourth, self-efficacy was found to have a mediating effect in which women's constructive thinking strategies affect their intention to start a business. At this time, the medium effect was shown as a complete medium. This shows that the higher a woman's self-preservation, the higher her self-efficacy and willingness to start a business. Based on the results of these studies, he made a developed proposal for women's start-ups.