This study aimed to explore the effects of perceived family stress, supportive resources, intentional rumination, and coping behaviors on posttraumatic growth of cancer survivors based on the Double ABCX Family Stress Model. Data were collected from 200 cancer survivors currently living with their spouses and analyzed by path analysis using AMOS program. The results of this study were as follows. First, perceived family stress of cancer survivors had direct effects on supportive resources, intentional rumination, and coping behaviors, and had indirect effects on posttraumatic growth mediated by supportive resources, intentional rumination, and coping behaviors. Second, supportive resources, intentional rumination, and coping behaviors had direct effects on posttraumatic growth. Third, supportive resources and intentional rumination had direct effects on coping behaviors and had an indirect effect on posttraumatic growth mediated by coping behaviors. The current study supported the applicability of the Double ABCX Family Stress Model to the posttraumatic growth process of cancer survivors.