This study was carried out to analyze and compare job satisfaction, job stress, burnout, and turnover intention of comprehensive nursing care service ward nurses and general ward nurses. The participants were 181 nurses from six hospitals providing comprehensive nursing care service in G metropolitan city. The data were collected using structured questionnaires in May 16-June 30, 2017. The data were analyzed with SPSS program, which was used for t-test, one-way ANOVA, and Pearson's correlation. As a result, there were no significant differences in the variables between comprehensive nursing care service ward nurses and general ward nurses. However, comprehensive nursing care service ward nurses had higher job satisfaction, lower job stress, lower burnout, and lower turnover intention than general ward nurses. There was a significant relationship between job stress (r=.39, p=<.001), burnout (r=.43, p=<.001), job satisfaction (r=-.66, p=<.001), and turnover intention. Comprehensive nursing care service ward nurses were more positive about their nursing work than general ward nurses. The findings of this study can be used as basic data for effective nursing resource management in a comprehensive nursing care service ward.