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Sericin and 4-hexylresorcinol combination ointment accelerates wound healing in the diabetic burn wound model

  • Kang, Yei-Jin (Dept. of Oral and Maxillofacial Surgery, College of Dentistry, Gangneung-Wonju National University) ;
  • Jo, You-Young (Sericultural and Apicultural Materials Division, National Institute of Agricultural Sciences, RDA) ;
  • Kweon, HaeYong (Sericultural and Apicultural Materials Division, National Institute of Agricultural Sciences, RDA) ;
  • Kim, Seong-Gon (Dept. of Oral and Maxillofacial Surgery, College of Dentistry, Gangneung-Wonju National University)
  • Received : 2020.02.10
  • Accepted : 2020.02.27
  • Published : 2020.03.31

Abstract

Sericin has been used for the treatment of burn wound. The purpose of this study was to compare the wound healing between sericin plus 4-hexylresorcinol (4HR) ointment (SE+4HR) and base only ointment. Total 12 mice were included in this study. SE+4HR group showed significantly smaller wound size than base only group at 3 wk (P<0.05). Surface temperature was higher in SE+4HR group. In conclusion, SE+4HR group showed better wound healing than base only group.

Acknowledgement

Supported by : Rural Development Administration

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