The Skin-Related Biological Activities of Aerially Extract of Oenothera lamarckiana

큰달맞이꽃 지상부 추출물의 피부 관련 생리활성 효과

  • Yang, Ji Yeong (Department of Biomedical Laboratory Science, College of Health Sciences, Yonsei University) ;
  • Kim, Jin Woo (School of Industrial Bio-pharmaceutical Science, Semyung University) ;
  • Lee, Pyeongjae (School of Industrial Bio-pharmaceutical Science, Semyung University)
  • 양지영 (연세대학교 보건과학대학 임상병리학과) ;
  • 김진우 (세명대학교 바이오제약산업학부) ;
  • 이평재 (세명대학교 바이오제약산업학부)
  • Received : 2019.08.26
  • Accepted : 2019.10.21
  • Published : 2019.10.31


Skin plays important roles in protecting the internal organs from the chemical-biological risk factors and ultraviolet light. Exposure to the chemical and biological stimuli has a detrimental effect on skin's structure and physiological regulation. Therefore, much attention has been paid to natural products that show biological activities such as anti-oxidation, anti-aging and anti-bacterial activities. In this study, we investigated the skin-related biological activities of Oenothera lamarckiana aerial part extract. The extract contained 229.35 mg TAE (tannic acid equivalents)/g total polyphenolic compounds and the extract showed relative high antioxidant activity ($SC_{50}$ value: $8.52{\mu}g/mL$). The $IC_{50}$ value against tyrosinase and elastase were 307.94 and $181.51{\mu}g/mL$, respectively. This suggested that O. lamarckiana can be applied to whiten skin and slow the aging of skin. O. lamarckiana extract showed a growth inhibitory effect on Staphylococcu epidermidis (minimum inhibitory concentration: $250{\mu}g/mL$). Interestingly, O. lamarckiana extract showed no inhibitory effect on Pseudomonas aeruginosa on the paper disc assay. Yet the extract inhibited the growth of Pseudomonas aeruginosa on the broth dilution assay in a dose-dependent manners. Taken together, O. lamarckiana could have good potential for development as an additive in the cosmetic industry.


Oenothera lamarckiana;anti-oxidation;anti-aging;anti-bacterial activity


Supported by : 세명대학교


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