A study on Antibacterial Activity of Samsinhwan Ethanol Extract against MRSA

삼신환(三神丸) 에탄올 추출물(SSH)의 MRSA에 대한 항균활성 연구

  • Woo, Haksik (Wonkwang University Graduate School of Traditional Chinese Medicine) ;
  • Lee, Yeoung Ju (Department of Medicinal Crops, Dongbang Culture Univercity)
  • 우학식 (원광대학교 한의학전문대학원) ;
  • 이영주 (동방문화대학교 약용작물학과)
  • Received : 2019.05.31
  • Accepted : 2019.08.20
  • Published : 2019.08.28


The purpose of this study is to identify the antimicrobial effects of SSH(三神丸) and synerggy effects of the existing antibiotics Oxacillin and Ciprofloxacin on MRSA and to identify the mechanisms. In this case, the procedure and method for verifying anti-bacterial activity and active concentration of MARA by measuring the minimum inhibitory concentration (MIC) of the trichin is used to verify the potency and active concentration of MARA, to confirm the potency of the disease by treating antibiotics and trichine ethanol extract in parallel, and to confirm the anti-bacterial effect over time, when the trichine is activated as an anti-bacterial activity to MARA, and a compound. In addition, we hope that this research will not only serve as meaningful data for the development of new drugs to control MARA immunity, but also serve as an opportunity to further accelerate the research and development of antibiotics to overcome resistant strains.


Samsin-hwan;MRSA;Antibacterial Activity;disc diffusion method;MIC


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