Fig. 1. lncRNA PVT1 was upregulated in abdominal aortic tissues from AAA patients and ApoE-/- AAA models.
Fig. 2. Relative PVT1 expression in Ang IIinduced VSMCs and the effect of PVT1 expression on Ang II-induced apoptosis.
Fig. 3. Effects of PVT1 expression on ECM degradation and phenotype switching of Ang II-induced VSMCs.
Fig. 4. sh-PVT1 attenuated Ang II-induced AAA in mice.
Fig. 5. sh-PVT1 attenuated Ang II-induced PVT1 expression, ECM degradation, and inflammation in mice.