- Volume 50 Issue 4
DOI QR Code
A Novel Prognostic Nomogram for Predicting Risks of Distant Failure in Patients with Invasive Breast Cancer Following Postoperative Adjuvant Radiotherapy
- Lim, Yu Jin (Department of Radiation Oncology, Seoul National University Bundang Hospital) ;
- Lee, Sea-Won (Department of Radiation Oncology, Seoul National University Bundang Hospital) ;
- Choi, Noorie (Department of Radiation Oncology, Seoul National University Bundang Hospital) ;
- Kwon, Jeanny (Department of Radiation Oncology, Seoul National University Bundang Hospital) ;
- Eom, Keun-Yong (Department of Radiation Oncology, Seoul National University Bundang Hospital) ;
- Kang, Eunyoung (Breast Care Center, Seoul National University Bundang Hospital, Seoul National College of Medicine) ;
- Kim, Eun-Kyu (Breast Care Center, Seoul National University Bundang Hospital, Seoul National College of Medicine) ;
- Kim, Jee Hyun (Breast Care Center, Seoul National University Bundang Hospital, Seoul National College of Medicine) ;
- Kim, Yu Jung (Breast Care Center, Seoul National University Bundang Hospital, Seoul National College of Medicine) ;
- Kim, Se Hyun (Breast Care Center, Seoul National University Bundang Hospital, Seoul National College of Medicine) ;
- Park, So Yeon (Breast Care Center, Seoul National University Bundang Hospital, Seoul National College of Medicine) ;
- Kim, In Ah (Department of Radiation Oncology, Seoul National University Bundang Hospital)
- Received : 2017.10.24
- Accepted : 2017.12.05
- Published : 2018.10.15
Purpose This study aimed to identify predictors for distant metastatic behavior and build a related prognostic nomogram in breast cancer. Materials and Methods A total of 1,181 patients with non-metastatic breast cancer between 2003 and 2011 were analyzed. To predict the probability of distant metastasis, a nomogram was constructed based on prognostic factors identified using a Cox proportional hazards model. Results The 7-year overall survival and 5-year post-progression survival of locoregional versus distant recurrence groups were 67.6% versus 39.1% (p=0.027) and 54.2% versus 33.5% (p=0.043), respectively. Patients who developed distant metastasis showed early and late mortality risk peaks within 3 and after 5 years of follow-up, respectively, but a broad and low risk increment was observed in other patients with locoregional relapse. In multivariate analysis of distant metastasis-free interval, age (
Supported by : Korean Ministry of Science and Information & Communication Technology
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