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Enhancing Production Rate of Emulsion via Parallelization of Flow-Focusing Generators

유동-집속 생성기의 병렬화를 통한 에멀젼 생산속도 향상

  • Jeong, Heon-Ho (Department of Chemical and Biomolecular Engineering, Chonnam National University)
  • 정헌호 (전남대학교 화공생명공학과)
  • Received : 2018.07.10
  • Accepted : 2018.08.31
  • Published : 2018.10.01

Abstract

Droplet-based microfluidic device has led to transformational new approaches in various applications including materials synthesis and high-throughput screening. However, efforts are required to enhance the production rate to industrial scale because of low production rate in a single droplet generator. In here, we present a method for enhancing production rate of monodisperse droplets via parallelization of flow-focusing generators. For this, we fabricated a three-dimensional monolithic elastomer device (3D MED) that has the 3D channel structures in a single layer, using a double-sided imprinting method. We demonstrated that the production rate of monodisperse droplet is increased by controlling the flow rate of continuous and dispersed phases in 3D MED with 8 droplet generators. Thus, we anticipate that this microfluidic system will be used in wide area including microparticle synthesis and screening system via encapsulation of various materials and cells in monodisperse droplets.

Keywords

Microfluidic device;Emulsion;Parallelization;Scale-up

Acknowledgement

Supported by : 한국연구재단

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