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Effect of single nucleotide polymorphisms on intramuscular fat content in Hungarian Simmental cattle

  • Anton, Istvan (NARIC-Research Institute for Animal Breeding Nutrition and Meat Science) ;
  • Huth, Balazs (Department of Animal Husbandry and Management, Institute of Animal Science, Faculty of Agricultural and Environmental Sciences, University of Kaposvar) ;
  • Fuller, Imre (Association of Hungarian Simmental Cattle Breeders) ;
  • Rozsa, Laszlo (NARIC-Research Institute for Animal Breeding Nutrition and Meat Science) ;
  • Hollo, Gabriella (Department of Animal Husbandry and Management, Institute of Animal Science, Faculty of Agricultural and Environmental Sciences, University of Kaposvar) ;
  • Zsolnai, Attila (NARIC-Research Institute for Animal Breeding Nutrition and Meat Science)
  • Received : 2017.10.19
  • Accepted : 2018.03.12
  • Published : 2018.09.01

Abstract

Objective: To estimate effect of single nucleotide polymorphisms on the intramuscular fat content (IMF) of Hungarian Simmental bulls. Methods: Genotypes were determined on high-density Illumina Bovine DNA Chip. After slaughtering of animals, chemical percentage of intramuscular fat was determined from longissimus dorsi muscle. A multi-locus mixed-model was applied for statistical analyses. Results: Analyses revealed four loci (rs43284251, rs109210955, rs41630030, and rs41642251) to be highly associated ($-{\log}_{10}P$>12) with IMF located on chromosome 1, 6, 13, and 17, respectively. The frequency of their minor alleles was 0.426, 0.221, 0.162, and 0.106. Conclusion: The loci above can be useful in selection programs and gives the possibility to assist selection by molecular tools.

Keywords

Cattle;Single Nucleotide Polymorphism;Genome-wide Association Study (GWAS);Fat

Acknowledgement

Supported by : Hungarian Scientific Research Fund

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