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Dietary spray-dried plasma improves intestinal morphology of mated female mice under stress condition

  • Liu, Yanhong (Department of Animal Science, University of California) ;
  • Choe, Jeehwan (Department of Animal Science and Biotechnology, Chungnam National University) ;
  • Kim, Sheena (Department of Animal Science and Biotechnology, Chungnam National University) ;
  • Kim, Byeonghyeon (Department of Animal Science and Biotechnology, Chungnam National University) ;
  • Campbell, Joy M. (APC Inc.) ;
  • Polo, Javier (APC Inc.) ;
  • Crenshaw, Joe D. (APC Inc.) ;
  • Pettigrew, James E. (Department of Animal Sciences, University of Illinois) ;
  • Song, Minho (Department of Animal Science and Biotechnology, Chungnam National University)
  • Received : 2018.01.26
  • Accepted : 2018.04.23
  • Published : 2018.06.30

Abstract

Background: Stress causes inflammation that impairs intestinal barrier function. Dietary spray-dried plasma (SDP) has recognized anti-inflammatory effects and improvement of gut barrier function. Therefore, the purpose of this study was to investigate the effects of dietary SDP on intestinal morphology of mated female mice under stress condition. Results: Villus height, width, and area of small intestines were low on gestation day (GD) 3 or 4 under stress conditions, and higher later (Time, P < 0.05). Crypt depth of colon was low on GD 4 and higher later (Time, P < 0.05). Meanwhile, the SDP treatments improved (P < 0.05) intestinal morphology, indicated by increased villus height, villus width, villus area, and ratio between villus height and crypt depth of small intestines and crypt depth of colon, and by decreased crypt depth of small intestines, compared with the control diet. The SDP treatments also increased (P < 0.05) the number of goblet cells in intestines compared with the control diet. There were no differences between different levels of SDP. Conclusion: Dietary SDP improves intestinal morphology of mated female mice under stress condition.

Keywords

Intestinal morphology;Mated female mice;Spray-dried plasma;Stress

Acknowledgement

Supported by : Chungnam National University

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