Clinical and Hematologic Characteristics of Temporomandibular Disorders Patients

  • Park, Seo Eun (Department of Oral Medicine and Oral Diagnosis, School of Dentistry and Dental Research Institute, Seoul National University) ;
  • Kim, Ji Rak (Department of Dentistry and Oral Medicine, School of Medicine, Catholic University of Daegu) ;
  • Jo, Jung Hwan (Department of Oral Medicine, Seoul National University Dental Hospital) ;
  • Park, Ji Woon (Department of Oral Medicine and Oral Diagnosis, School of Dentistry and Dental Research Institute, Seoul National University)
  • Received : 2018.05.31
  • Accepted : 2018.06.22
  • Published : 2018.06.30


Purpose: The aim of this study was to evaluate the possibility of utilizing blood tests for the diagnosis of temporomandibular disorders (TMDs) by investigating the hematologic characteristics of TMD patients according to the main source and level of TMD pain and analyzing their interrelationship. Methods: Clinical examination following the research diagnostic criteria for TMD and hematological and psychological evaluations were conducted in 357 TMD patients. Patients were divided into groups according to the main source of pain (myogenous, arthrogenous, and combined pain) and the degree of pain according to the graded chronic pain scale (GCPS). Hematological differences among the groups were statistically analyzed. Results: The C-reactive protein (CRP) level was significantly higher in the arthrogenous pain group compared to the combined pain group (p=0.032). There was no significant difference according to the GCPS classification. There were significant correlations between some of the TMD pain indices and the hematologic indices, and also between the psychological indices and the hematologic indices. Conclusions: This study suggests the possibility of applying blood tests to the diagnosis, treatment and prevention of TMD. Further research should be conducted focusing on the role of CRP in TMD pain with more refined methodology and a longitudinal study design.


C-reactive protein;Hematologic tests;Pain;Temporomandibular disorders


Supported by : Seoul National University (SNU)


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