- Volume 21 Issue 2
DOI QR Code
An integrated approach with homeopathic medicine and electro-acupuncture in anaesthesiology during breast cancer surgery: Case reports
- Bosco, F (S.D. Anaesthesia and Intensive Care MiSC AOUP Complementary Medicine Oncology Integrated Breast Unit, University Hospital Trust of Pisa) ;
- Cidin, S (S.D. Anaesthesia and Intensive Care MiSC AOUP Complementary Medicine Oncology Integrated Breast Unit, University Hospital Trust of Pisa) ;
- Maceri, F (S.D. Anaesthesia and Intensive Care MiSC AOUP Complementary Medicine Oncology Integrated Breast Unit, University Hospital Trust of Pisa) ;
- Ghilli, M (Breast Cancer Surgical Unit, University Hospital Trust of Pisa) ;
- Roncella, M (Breast Cancer Surgical Unit, University Hospital Trust of Pisa) ;
- De Simone, L (S.D. Anaesthesia and Intensive Care MiSC AOUP Complementary Medicine Oncology Integrated Breast Unit, University Hospital Trust of Pisa)
- Received : 2017.09.12
- Accepted : 2018.05.17
- Published : 2018.06.30
This study investigates the effect of a combination of homeopathic medicine and electro- acupuncture in two patients with breast cancer and severe liver disease who could not receive standard anaesthesia therapy due to liver problems. Specifically, measurable and quantifiable parameters were used to evaluate whether an integrated approach-consisting of electro- acupuncture and a homeopathic medicine diluted above Avogadro's limit (that is, above a potency of 12CH) during the pre-surgical, surgical and post-surgical phases -can improve general well-being of a patient undergoing breast cancer surgery. In breast cancer surgery, we employed an integrated approach consisting of induction with hypnotics and muscle relaxants, followed by maintenance with anaesthetic gas, combined with a homeopathic treatment (Arnica montana 15CH and Apis mellifica 15CH) before and after surgery and an electro- acupuncture treatment performed in the pre- and post-surgical phases without any analgesic/pain relieving medications. Both of the patients treated with the integrated approach improved their overall condition without need for other common pain relieving medicines. Additionally, thanks to their rapid awakening, the patients were not relocated to a protected area and the hospitalization was shorter. A multidisciplinary approach incorporating homeopathic medicine and electro-acupuncture can be a solution for patients who need or ask about a different and/or safer alternative to the standard treatment. This approach can offer a safe, much less expensive, non-invasive and viable alternative for such cases. Moreover it can be useful for an opioids free anesthesia.
- Kehlet H, Dahl JB. Anaesthesia, surgery, and challenges in postoperative recovery. Lancet. 2003; 362: 1921-8. https://doi.org/10.1016/S0140-6736(03)14966-5
- Chao AS, Chao A, Wang TH, Chang YC, Peng HH, et al. Pain relief by applying transcutaneous electrical nerve stimulation (TENS) on acupuncture points during the frst stage of labor: a randomized double-blind place-bo-controlled trial. Pain. 2007. 127(3):214-20. https://doi.org/10.1016/j.pain.2006.08.016
- Iannitti T, Morales-Medina JC, Bellavite P, Rottigni V, Palmieri B Effectiveness and Safety of Arnica montana in Post-Surgical Setting, Pain and Inflammation. American Journal of Terapeutics. 2014.
- Robertson A, Suryanarayana N, Banerjee A. Homeopathic Arnica montana for post-tonsillectomy analgesia: a randomized placebo control trial. Homeopathy. 2007.
- Lao L, Bergman S, Hamilton GR et al. Evaluation of Acupuncture for Pain Control After Oral Surgery: A Place-bo-Controlled Trial. Arch Intern Med. 2009; 169 (9), 858.
- Practice Guidelines for Acute Pain Management in the Perioperative Setting Anesthesiology. 2012; 116 (2).
- Molassiotis A, Fernadez-Ortega P, Pud D, Ozden G, Scott JA et al. Use of complementary and alternative medicine in cancer patients: a European survey. Annals of Oncology. 2005; 16: 655-663. https://doi.org/10.1093/annonc/mdi110
- Bonacchi A, Fazzi L, Toccafondi A, Cantore M, Mambrini A et al. Use and Perceived Benefits of Complementary Terapies by Cancer Patients Receiving Conventional Treatment in Italy. 2013.
- Rossi E, Vita A, Baccetti S, et al. Complementary and alternative medicine for cancer patients: Results of the EPAAC survey on integrative oncology centres in Europe. Support Care Cancer. 2014.
- Filshie, J.; Hester, J. Guidelines for providing acupuncture treatment for cancer patients-A peer-reviewed sample policy document. Acupunct. Med. 2006, 24, 172-182. https://doi.org/10.1136/aim.24.4.172
- Tavares MG et al. Electro-Acupuncture Efcacy on Pain Control after Mandibular Tird Molar Surgery. Braz Dent J; 2007. 18(2): 158-162. https://doi.org/10.1590/S0103-64402007000200014
- Van Nghi N., Lanza U., Van Dong M. Teoria e pratica della analgesia con agopuntura. Ed. Alzani; Pinerolo; Torino; 1975.
- Han JS. Acupuncture: neuropeptide release produced by electrical stimulation of different frequencies. Trends Neurosci. 2003; 26(1):17-22 https://doi.org/10.1016/S0166-2236(02)00006-1
- Basbaum AI, Fields HL. Endogenous pain control systems: brainstem spinal pathways and endorphin circuitry. Annu Rev Neurosci. 1984; 7: 309-38. https://doi.org/10.1146/annurev.ne.07.030184.001521
- Kawakita K, Okada K. Mechanisms of action of acupuncture for chronic pain relief - polymodal receptors are the key candidates. Acupuncture in medicine. 2006; 24 (Suppl): S58-66. https://doi.org/10.1136/aim.24.Suppl.58
- Mayor D. Electroacupuncture: A Practical Manual and Resource. Ed. Livingstone; 2006.
- Sorrentino L, Piraneo S, Riggio E, et al. Is there a role for homeopathy in breast cancer surgery? A frst randomized clinical trial on treatment with Arnica Montana to reduce post-operative seroma and bleeding in patients undergoing total mastectomy. J Intercult Ethnopharmacol. 2017; 6(1):1e8.
- Mazzocchi A, Passi L. Retrospective Analysis of 736 implants inserted without antibiotic therapy. J. Oral Maxillofac Surg. 2007; 65: 2321-2323. https://doi.org/10.1016/j.joms.2007.06.620
- Wenzel F, Hoegn C, Rox J, Trapp T, Giers G, Fischer J. Homeopathic arnica as supportive therapy in bone marrow donation. Transfus Med Hemother. 2011; 38 (suppl 1):1-72.
- Berrebi A, Parant O, Ferval F, Tene M, Ayoubi JM, Connan J, Belon P. Traitement de la douleur de la montée laiteuse non souhaitee par homeopathie dans le post-partum immediat. J Gynecol Obstet Biol Reprod. 2001; 30: 353-357.
- Merfort I. Arnica: new insights on the molecular mode of action of a traditional medicinal plant; Forsch. Komple-mentarmed. Klass. Naturheilkd. 2003; 10; 45-48.
- Lyss G, Knorre A, Schmidt TJ, Pahl HL.The Anti-inflammatory Sesquiterpene Lactone Helenalin Inhibits the Transcription Factor NF-kB by Directly Targeting p65. The Journal of biological chemistry. 1998; 273(50): pp. 33508-33516. https://doi.org/10.1074/jbc.273.50.33508
- Sharma S, Arif M, Nirala RK, Gupta R, Takur SC. Cu-mulative therapeutic effects of phytochemicals in Arnica montana flower extract alleviated collagen-induced arthritis: inhibition of both pro-inflammatory mediators and oxidative stress. J Sci Food Agric. 2016; 96: 1500-1510. https://doi.org/10.1002/jsfa.7252
- Macedo SB, Ferreira LR, Perazzo FF, Carvalho JC. An-ti-inflammatory activity of Arnica montana 6CH: preclinical study in animals. Homeopathy 2004; 93: 84-87. PMID: 15139092.
- Nicollas R, Pondaven S, Giovanni A, Couloigner V, Tronche S, Recommandation pour la pratique Clinique. Societe Francaise d'Anesthesie Reanimation; 2000.
- Marzotto M, Bonafni C, Olioso D, Baruzzi A, Bettinet- ti L, Di Leva F, Galbiati E, Bellavite P. Arnica montana Stimulates Extracellular Matrix Gene Expression in a Macrophage Cell Line Differentiated to Wound-Healing Phenotype. Plos one. 2016; 11: e0166340. https://doi.org/10.1371/journal.pone.0166340
- Bigagli E, Luceri C, Dei A, Bernardini S, Dolara P. Effects of Extreme Dilutions of Apis mellifica Preparations on Gene Expression Profiles of Human Cells. Dose-Re-sponse: An International Journal. 2016:1-7