Effects of combined exercise on the blood inflammatory factors, DHEA-s and arterial stiffness of elderly women

복합운동이 고령여성의 혈중 염증인자, DHEA-s 및 동맥경직도에 미치는 영향

  • Ha, Soo-Min (Department of Physical Education, Pusan National University) ;
  • Kim, Jung-Sook (Department of Physical Education, Pusan National University) ;
  • Kim, Ji-Hyeon (Department of Physical Education, Pusan National University) ;
  • Kim, Do-Yeon (Department of Physical Education, Pusan National University)
  • 하수민 (부산대학교 체육교육과) ;
  • 김정숙 (부산대학교 체육교육과) ;
  • 김지현 (부산대학교 체육교육과) ;
  • 김도연 (부산대학교 체육교육과)
  • Received : 2018.11.30
  • Accepted : 2018.12.17
  • Published : 2018.12.31


The purpose of this study was to investigate the effects of combined exercise on blood inflammatory factors, DHEA-s and arterial stiffness in elderly women. The subjects were 42 elderly females volunteers, aged 70 to 85 years, composed of the combined exercise group (n=21) and control group (n=21). The 60 minute combined exercise program(aquarobics 1 time/week, strength exercise 2 times/week) was performed 3 times per week for 12 weeks, and the intensity was progressively increased every 4 weeks(1-4 weeks: RPE 12 to 13, 5-8 weeks: RPE 13 to 14, 9-12weeks: RPE 14 to 15). The test data were analyzed by two-way repeated measures ANOVA, paired t-test, independent t-test and the alpha level of .05 was set for all tests of significance. As a result, the combined exercise for 12 weeks reduced the inflammatory response of elderly women, and DHEA-s was found to have a positive effect on aging hormone. The arterial stiffness decreased the central arterial blood pressure (systolic and diastolic), prevented the increase of the pulse pressure and the wave increase index, and decreased the pulse wave velocity. These results suggest that regular and continuous combined exercise may be recommended for the healthy aging and longevity of elderly women by inducing anti-inflammation effect and improving the aging hormonal function and the vascular health.

본 연구는 만 70~85세의 고령여성을 대상으로 주 1회 아쿠아로빅과 주 2회 맨손근력운동을 실시하는 복합운동프로그램을 12주간 적용하여 혈중 염증인자, DHEA-s 및 동맥경직도에 미치는 영향을 구명하기 위하여 운동군 21명, 대조군 21명으로 구분하여 실시하였다. 1회 운동지속시간은 60분으로 4주 간격으로 운동강도를 점진적으로 증가시켜 실시하였다. 복합운동 전과 후에 측정된 자료의 상호작용 효과 검증을 위해 이원반복측정 분산분석을 실시하였고, T검정을 사용하여 사후분석을 하였으며, 유의수준은 .05로 설정하여 분석하였다. 그 결과 12주간의 복합운동은 고령여성의 염증반응을 감소 시켰으며, DHEA-s가 증가함에 따라 노화호르몬에도 긍정적인 영향을 미치는 것으로 나타났다. 동맥경직도는 중심동맥혈압(수축기, 이완기)이 감소하였고, 맥압 및 파형증가지수의 증가를 완화하였으며, 맥파전파속도를 감소시키는 것으로 나타났다. 이상의 결과 고령여성의 건강한 노화와 장수를 위해서 항염증, 노화호르몬의 개선 및 혈관건강의 역할로 규칙적이고 지속적인 복합운동이 권장 될 수 있을 것으로 사료된다.


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Fig. 1. Changes in blood inflammatory factors after 12-week combined exercise.

Table 1. Physical characteristics of subjects in each groups

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Table 2. Combined exercise program

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Table 3. Changes in blood inflammatory factors after 12-week combined exercise

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Table 4. Changes in arterial stiffness after 12-week combined exercise

HGOHBI_2018_v35n4_1096_t0004.png 이미지


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