Long-Term Complications of Radiotherapy in a Patient with Maxillary Squamous Cell Carcinoma: A Matter of Trismus and Osteoradionecrosis

  • Kim, Keon-Hyung (Department of Oral Medicine, College of Dentistry, Dankook University) ;
  • Park, Jo-Eun (Department of Oral Medicine, College of Dentistry, Dankook University) ;
  • Kim, Mee-Eun (Department of Oral Medicine, College of Dentistry, Dankook University) ;
  • Kim, Hye-Kyoung (Department of Oral Medicine, College of Dentistry, Dankook University)
  • Received : 2018.09.08
  • Accepted : 2018.11.29
  • Published : 2018.12.30


Oral cancer is a malignant neoplasm of the lips or oral cavity. Surgery, radiotherapy and chemotherapy depending on the location and stage of the tumor can be considered as important treatment modalities of oral cancer. Unfortunately, all three treatments can have both acute and chronic complications. Among them, trismus and osteoradionecrosis (ORN), unique complications of radiotherapy in the orofacial region, are particularly difficult to treat once manifested. Therefore, these two complications of radiotherapy have devastating effects on the patient's oral health and furthermore, overall quality of life. In this study, we present a case of a patient showing trismus and ORN following radiotherapy for the treatment of maxillary squamous cell carcinoma and briefly discuss this matter of trismus and ORN in the perspective of a dentist.

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Fig. 1. Panoramic view before maxillectomy on the left side. Partial destruction and diffuse bone resorption are observed on the left posterior maxillary alveolar bone.

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Fig. 2. Computerized tomography image of the patient. Partial destruction and diffuse bone resorption are observed on the left posterior maxillary alveolar bone.

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Fig. 3. Panoramic view after maxillary resection on the left side.

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Fig. 4. Progression of the amount of active range of motion (AROM).

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Fig. 5. Whole body bone scan image. Hot spot can be seen on the left mandible. ANT, anterior; POST, posterior.


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