A Convergence HRV Analysis for Significant Factor Diagnosing in Adult Patients with Sleep Apnea

수면무호흡을 가진 성인환자들의 주요인자 진단을 위한 융합 심박변이도 해석

  • Kim, Min-Soo (Department of Aviation Information & Communication Eng. Kyungwoon University) ;
  • Jeong, Jong-Hyeog (Department of Aviation Information & Communication Eng. Kyungwoon University) ;
  • Cho, Young-Chang (Department of Aviation Information & Communication Eng. Kyungwoon University)
  • 김민수 (경운대학교 항공정보통신공학과) ;
  • 정종혁 (경운대학교 항공정보통신공학과) ;
  • 조영창 (경운대학교 항공정보통신공학과)
  • Received : 2017.11.13
  • Accepted : 2018.01.20
  • Published : 2018.01.28


The aim of this study was to determine the statistical significance of heart rate variability(HRV) between sleep stages, Apnea-hypopnea index(AHI) and age in patients with obstructive sleep apnea(OSA). This study evaluated the main parameters of HRV over time domain and frequency domain in 40 patients with sleep apnea. The non-REM(sleep stage) was statistically validated by comparing the AHI degree of the three groups(mild, moderate, severe) of sleep apnea patients. The NN50(p=0.043), pNN50(p=0.044), VLF peak(p=0.022), LF/HF(p=0.028) were statistically significant in the R-R interval of patients with sleep apnea from the control group (p<0.05). The LF / HF (p = 0.045) and HF power (p = 0.0395) parameters between the non-RAM sleep (sleep 2 phase) and REM sleep in patients with sleep apnea were statistically significant in the control group(p<0.05). We may be able to provide a basis for understanding the correlation among AHI, sleep stage and age and heart rate variability in patients with obstructive sleep apnea.


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