Fig. 1. PI activates IκB/NF-κB pathway.
Fig. 2. PI-induced IκBα degradation is associated with macroautophagy.
Fig. 3. Macroautophagy mediates PI-induced IκBα degradation.
Fig. 4. PI-induced IκBα degradation is mediated by Nrf2 up-regulation via both de novo protein synthesis and KEAP1 degradation.
Fig. 5. PI-induced Nrf2 activation suppresses PI-induced cell death.