추출용매에 따른 영지버섯(Ganoderma lucidum)의 항산화 및 소화효소 저해활성

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주옥수;황정은;홍수영;신의철;남상해;조계만
Joo, Ok Soo;Hwang, Chung Eun;Hong, Su Young;Sin, Eui Cheol;Nam, Sang Hae;Cho, Kye Man

  • 투고 : 2018.01.31
  • 심사 : 2018.02.20
  • 발행 : 2018.02.28

초록

본 연구는 영지버섯(Ganoderma lucidum)의 영양학적 특성과 생리활성을 조사하였다. 탄수화물 함량은 원형 영지버섯이 높았고 조회분, 조지방, 조단백질 및 무기질 함량은 녹각 영지버섯이 높았다. 주요 아미노산, 지방산, 무기질 및 수용성 비타민은 valine(원형: 11.90 mg/g 및 녹각: 17.18 mg/g), linoleic acid(원형: 47.56% 및 녹각: 75.68%), 칼륨(원형: 116.50 mg/100 g 및 녹각: 184.36 mg/100 g) 및 비타민 $B_3$(원형: 1.78 mg/100 g 및 녹각: 1.81 mg/100 g) 있었다. 한편 ${\beta}$-glucan 함량은 각각 34.15 g/100 g(원형)과 30.07 g/100 g(녹각)로 검출되었다. 추출조건 중 $40^{\circ}C-70%$ 에탄올 추출물에서 가장 우수한 라디칼 소거활성과 탄수화물 및 지방분해 효소 저해활성을 나타내었다. 특히, $40^{\circ}C-70%$ 에탄올로 추출한 원형영지버섯의 1 mg/mL 처리 시 DPPH, ABTS 및 hydroxyl 라디칼 소거활성과 ${\alpha}$-glucosidase, ${\alpha}$-amylase 및 pancreatic lipase 저해활성은 각각 92.85, 99.74, 58.09, 89.68, 44.68, 67.56%로 나타났다.

키워드

Ganoderma lucidum;ethanolic extracts;antioxidant activity;${\alpha}$-glucosidase inhibitory activity;pancreatic lipase inhibitory activity

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과제정보

연구 과제 주관 기관 : 농림축산식품부