건조방법에 따른 미선나무 잎의 항산화 및 항염증 효과



Chang, Seong Jun;Jeon, Nam Bae;Park, Joo Won;Jang, Tae Won;Jeong, Jin Boo;Park, Jae Ho

  • 투고 : 2017.12.06
  • 심사 : 2018.01.26
  • 발행 : 2018.02.28


건조 방식에 따른 미선나무 잎의 항산화 활성 및 항염증 효과를 확인한 결과, 높은 항산화 활성를 나타냈으며, 건조 잎에 비해 생잎의 항산화 활성이 뛰어났다. 페놀류 화합물의 함량은 유의적인 차이가 없었으나, 미선나무의 활성물질로 알려진 acteoside의 함량을 분석한 결과, 생잎의 acteoside의 함량이 높았다. 또한 항염증 효과를 확인하기 위해 nitric oxide의 함량 및 세포 수준에서의 염증 관련 인자인 iNOS와 COX-2의 단백질 발현 및 mRNA 수준을 확인한 결과, 생잎의 억제활성이 건조잎보다 높았다. 이를 통해 건조 잎에 비해 생잎의 이용가치가 높았으며, 이러한 항산화 및 항염증 활성은 acteoside의 함량의 차이와 밀접한 관련이 있는 것으로 사료된다.


Abeliophyllum distichum;anti-inflammatory;drying methods;iNOS


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