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Analysis of Treatment and Delay Times by Disease Site and Delivery Technique at Samsung Medical Center - Proton Therapy Center

  • Jo, Kwanghyun (Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Ahn, Sung Hwan (Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Chung, Kwangzoo (Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Cho, Sungkoo (Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Shin, Eunhyuk (Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Hong, Chae-Seon (Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Park, Seyjoon (Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Kim, Dae-Hyun (Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Lee, Boram (Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Lee, Woo-Jin (Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Seo, Se-Kwang (Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Jang, Jun-Young (Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Choi, Doo Ho (Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Lim, Do Hoon (Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Han, Youngyih (Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine)
  • Received : 2016.09.19
  • Accepted : 2016.12.24
  • Published : 2016.12.31

Abstract

We have treated various disease sites using wobbling and scanning proton therapy techniques since December 2015 at the Samsung Medical Center. In this study, we analyze the treatment time for each disease site in 65 wobbling and 50 scanning patient treatments. Treatment times are longest for liver and lung patients using the respiratory gating technique in the wobbling treatment and for cranio-spinal irradiation in pediatric patients with anesthesia in the scanning treatment. Moreover, we analyze the number of incidents causing treatment delays and the corresponding treatment delay time. The X-ray panel was the main reason for delays in the wobbling treatment; this decreased continually from January to June 2016, related closely to the proficiency of the human operators involved. The main reason for delays in the scanning treatment was interlocks during scanning pattern delivery; this was resolved by proton machine engineers. Through this work, we hope to provide other institutes with useful insight for initial operation of their proton therapy machines.

References

  1. Lodge M, et al: A systematic literature review of the clinical and cost-effectiveness of hadron therapy in cancer. Radiother Oncol 83(2): 110-122 (2007) https://doi.org/10.1016/j.radonc.2007.04.007
  2. Goitein M, Jermann M: The relative costs of proton and X-ray radiation therapy. Clin Oncol (R Coll Radiol) 15(1): S37-50 https://doi.org/10.1053/clon.2002.0174
  3. Peeters A, Grutters JP, et al: How costly is particle therapy? Cost analysis of external beam radiotherapy with carbon-ions, protons and photons. Radiother Oncol 95(1):45-53 (2010) https://doi.org/10.1016/j.radonc.2009.12.002
  4. SUZUKI K, et al: Quantitative analysis of beam delivery parameters and treatment process time for proton beam therapy. Med Phys 38(7): 4329-4337 (2011) https://doi.org/10.1118/1.3604153
  5. SUZUKI K, et al: Quantitative analysis of treatment process time and throughput capacity for spot scanning proton therapy. Med Phys 43(7): 3975-3986 (2016) https://doi.org/10.1118/1.4952731
  6. Chung K, Han Y, et al: The first private-hospital based proton therapy center in Korea; status of the Proton Therapy Center at Samsung Medical Center. Radiat Oncol J 33(4): 337-343 (2015) https://doi.org/10.3857/roj.2015.33.4.337
  7. Nguyen PL, Zietman AL: High-dose external beam radiation for localized prostate cancer: current status and future challenges. Cancer J 13:295-301 (2007) https://doi.org/10.1097/PPO.0b013e318156dbe3
  8. Zietman AL, DeSilvio ML, Slater JD, et al: Comparison of conventional-dose vs high-dose conformal radiation therapy in clinically localized adenocarcinoma of the prostate: a randomized controlled trial. JAMA 294:1233-9 (2005) https://doi.org/10.1001/jama.294.10.1233
  9. Slater JD, Rossi Jr CJ, Yonemoto LT, et al: Proton therapy for prostate cancer: the Initial Loma Linda University experience. Int J Radiat Oncol Biol Phys 59:348-52 (2004) https://doi.org/10.1016/j.ijrobp.2003.10.011
  10. Bush DA, Slater JD, Shin BB, Cheek G, Miller DW, Slater JM: Hypofractionated proton beam radiotherapy for stage I lung cancer. Chest 126: 1198-203 (2004) https://doi.org/10.1378/chest.126.4.1198
  11. Hata M, Tokuuye K, Kagei K, et al: Hypofractionated high-dose proton beam therapy for stage I non-small-cell lung cancer: preliminary results of a phase I/II clinical study. Int J Radiat Oncol Biol Phys 68:786-93 (2007) https://doi.org/10.1016/j.ijrobp.2006.12.063
  12. Orecchia R, Zurlo A, Loasses A, et al: Particle beam therapy (hadrontherapy):basis for interest and clinical experience. Eur J Cancer 34:459-68 (1998) https://doi.org/10.1016/S0959-8049(97)10044-2
  13. Laramore GE: Role of particle radiotherapy in the management of head and neck cancer. Curr Opin Oncol 21:224-31 (2009) https://doi.org/10.1097/CCO.0b013e328329b716
  14. Jereczek-Fossa BA, Krengli M, Orecchia R: Particle beam radiotherapy for head and neck tumors: radiobiological basis and clinical experience. Head Neck 28:750-60 (2006) https://doi.org/10.1002/hed.20448
  15. Hug EB, Sweeney RA, Nurre PM, Holloway KC, Slater JD, Munzenrider JE: Proton radiotherapy in management of pediatric base of skull tumors. Int J Radiat Oncol Biol Phys 52:1017-24 (2002) https://doi.org/10.1016/S0360-3016(01)02725-0
  16. Munzenrider JE, Liebsch NJ: Proton therapy for tumors of the skull base. Strahlenther Onkol 175:57-63 (1999)
  17. Noel G, Habrand JL, Jauffret E, et al: Radiation therapy for chordoma and chondrosarcoma of the skull base and the cervical spine. Prognostic factors and patterns of failure. Strahlenther Onkol 179:241-8 (2003) https://doi.org/10.1007/s00066-003-1065-5
  18. Van de Werf E, Verstraete J, Lievens Y: The cost of radiotherapy in a decade of technology evolution. Radiother Oncol 102(1):148-53 (2012) https://doi.org/10.1016/j.radonc.2011.07.033
  19. Van de Werf E, Lievens Y, et al: Time and motion study of radiotherapy delivery: Economic burden of increased quality assurance and IMRT. Radiother Oncol 93(1):137-40 (2009) https://doi.org/10.1016/j.radonc.2009.07.007
  20. Lievens Y, van den Bogaert W, Kesteloot K: Activitybased costing: a practical model for cost calculation in radiotherapy. Int J Radiat Oncol Biol Phys 57(2): 522-35 (2003) https://doi.org/10.1016/S0360-3016(03)00579-0