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Machine Learning Approach to Blood Stasis Pattern Identification Based on Self-reported Symptoms

기계학습을 적용한 자기보고 증상 기반의 어혈 변증 모델 구축

  • Kim, Hyunho (Department of Biofunctional Medicine & Diagnostics, College of Korean Medicine, Kyung Hee University) ;
  • Yang, Seung-Bum (Department of Medical Non-commissioned Officer, Wonkwang Health Science) ;
  • Kang, Yeonseok (Department of Medical History, College of Korean Medicine, Wonkwang University) ;
  • Park, Young-Bae (Department of Biofunctional Medicine & Diagnostics, College of Korean Medicine, Kyung Hee University) ;
  • Kim, Jae-Hyo (Department of Meridian & Acupoint, College of Korean Medicine, Wonkwang University)
  • 김현호 (경희대학교 한의과대학 진단생기능의학과학교실) ;
  • 양승범 (원광보건대학교 의무부사관과) ;
  • 강연석 (원광대학교 한의과대학 의사학교실) ;
  • 박영배 (경희대학교 한의과대학 진단생기능의학과학교실) ;
  • 김재효 (원광대학교 한의과대학 경혈학교실)
  • Received : 2016.06.07
  • Accepted : 2016.06.25
  • Published : 2016.09.27

Abstract

Objectives : This study is aimed at developing and discussing the prediction model of blood stasis pattern of traditional Korean medicine(TKM) using machine learning algorithms: multiple logistic regression and decision tree model. Methods : First, we reviewed the blood stasis(BS) questionnaires of Korean, Chinese, and Japanese version to make a integrated BS questionnaire of patient-reported outcomes. Through a human subject research, patients-reported BS symptoms data were acquired. Next, experts decisions of 5 Korean medicine doctor were also acquired, and supervised learning models were developed using multiple logistic regression and decision tree. Results : Integrated BS questionnaire with 24 items was developed. Multiple logistic regression models with accuracy of 0.92(male) and 0.95(female) validated by 10-folds cross-validation were constructed. By decision tree modeling methods, male model with 8 decision node and female model with 6 decision node were made. In the both models, symptoms of 'recent physical trauma', 'chest pain', 'numbness', and 'menstrual disorder(female only)' were considered as important factors. Conclusions : Because machine learning, especially supervised learning, can reveal and suggest important or essential factors among the very various symptoms making up a pattern identification, it can be a very useful tool in researching diagnostics of TKM. With a proper patient-reported outcomes or well-structured database, it can also be applied to a pre-screening solutions of healthcare system in Mibyoung stage.

Acknowledgement

Supported by : Small and Medium Business Administration

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