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Effect of KiFAY on Performance, Insulin-like Growth Factor-1, and Thyroid Hormones in Broilers

  • Kini, Amit (Vinayak Ingredients (India) Private Limited) ;
  • Fernandes, Custan (Vinayak Ingredients (India) Private Limited) ;
  • Suryawanshi, Dayaram (Omega Laboratories)
  • Received : 2016.03.07
  • Accepted : 2016.05.20
  • Published : 2016.10.01

Abstract

A comparative study was performed to investigate the efficacy of KiFAY as a feed additive on performance parameters, thyroid, and pancreatic hormone levels in broilers. Ninety birds (Vencobb 400) were randomly divided into three groups viz., Control (no DL-methionine supplementation), Treatment1 (containing added DL-methionine) and Treatment 2 (containing KiFAY and without DL-methionine supplementation). The performance parameters (weekly body weight, body weight gain, feed intake, and feed consumption ratio) were recorded and calculated during the whole study of 4 weeks. Analyses of insulin and insulin-like growth factor (IGF 1), triiodothyronine (T3), thyroxine (T4) and thyroid stimulating hormone (TSH) were performed at the end of the study. The results show that birds on supplementation of KiFAY performed significantly (p<0.001) better than other treatments. The weekly body weight, body weight gain, feed in-take and feed consumption ratio improved in KiFAY treated birds. The study found an increase in insulin and IGF1 levels (p<0.001) in KiFAY compared with the other treatments. Serum T3, T4, and TSH levels in the Treatment 2 were higher than other treatments (p<0.001). The KiFAY supplementation was able to improve performance with associated responses at a hormonal level in broilers.

Keywords

KiFAY;DL-methionine;Growth Performance;Thyroid Hormone;Insulin-like Growth Factor 1;Broilers

Acknowledgement

Supported by : Vinayak Ingredients (India) Private Limited

References

  1. Tsukada, A., T. Ohkubo, K. Sakaguchi, M. Tanaka, K. Nakashima, Y. Hayashida, M. Wakita, and S. Hoshino. 1998. Thyroid hormones are involved in insulin-like growth factor-I (IGF-I) production by stimulating hepatic growth hormone receptor (GHR) gene expression in the chicken. Growth Horm. IGF Res. 8:235-242. https://doi.org/10.1016/S1096-6374(98)80116-0
  2. Weurding, R. E., H. Enting, and M. W. Verstegen. 2003. The relation between starch digestion rate and amino acid level for broiler chickens. Poult. Sci. 82:279-284. https://doi.org/10.1093/ps/82.2.279
  3. Zhai, W., E. D. Peebles, X. Wang, P. D. Gerard, H. A. Olanrewaju, and Y. Mercier. 2016. Effects of dietary lysine and methionine supplementation on Ross 708 male broilers from 21 to 42 d of age (III): serum metabolites, hormones, and their relationship with growth performance. J. Appl. Poult. Res. 25:223-231. https://doi.org/10.3382/japr/pfw004
  4. Keusgen, M. 2002. Health and allium. In: Allium Crop Science:Recent Advances (Eds. H. D. Rabinowitch and L. Currah). Stratford-upon-Avon, CT, UK. pp. 357-373.
  5. King, D. B. and C. R. King. 1973. Thyroidal influence on early muscle growth of chickens. Gen. Comp. Endocrinol. 21:517-529. https://doi.org/10.1016/0016-6480(73)90112-3
  6. Meirelles, H. T., R. Albuquerque, L. M. O. Borgatti, L. W. O. Souza, N. C. Meister, and F. R. Lima. 2003. Performance of broilers fed with different levels of methionine hydroxy analogue and DL-methionine. Rev. Bras. Cienc. Avic. 5:69-74. https://doi.org/10.1590/S1516-635X2003000100009
  7. McGuinness, M. C. and L. A. Cogburn. 1990. Measurement of developmental changes in plasma insulin-like growth factor-I levels of broiler chickens by radioreceptor assay and radioimmunoassay. Gen. Comp. Endocrinol. 79:446-458. https://doi.org/10.1016/0016-6480(90)90075-W
  8. Melesse, A., S. Maak, R. Schmidt, and G. von Lengerken. 2011. Effect of long-term heat stress on key enzyme activities and T3 levels in commercial layer hens. Int. J. Livest. Prod. 2:107-116.
  9. Moravej, H., K. Homayoun, S. Mahmod, and M. Y. Hassan. 2006. Plasma concentrations of thyroid hormone and growth hormone in lohmann male broilers fed on different dietary energy and protein levels. Int. J. Poult. Sci. 5:457-462. https://doi.org/10.3923/ijps.2006.457.462
  10. Murray, R. K., D. K. Granner, P. A. Mayes, and V. W. Rodwell, 1998. Harper's Illustrated Biochemistry. Appleton Lana, Norwalk, CT, USA. pp. 610-617.
  11. NRC (National Research Council). 1994. Nutrient Requirements of Poultry. 9th rev. ed. National Academy Press, Washington, DC, USA.
  12. Pacheco, W. J., C. R. Stark, P. R. Ferket, and J. Brake. 2013. Evaluation of soybean meal source and particle size on broiler performance, nutrient digestibility, and gizzard development. Poult. Sci. 92:2914-2922. https://doi.org/10.3382/ps.2013-03186
  13. Rosebrough, R. W. and J. P. McMurtry. 2003. Methimzole and thyroid hormone replacement in broilers. Domest. Anim. Endocrinol. 24:231-242. https://doi.org/10.1016/S0739-7240(02)00236-9
  14. Rosebrough, R. W. and J. P. McMurtry. 1993. Protein and energy relationships in the broiler chicken. Effects of protein quantity and quality on metabolism. Br. J. Nutr. 70:667-678. https://doi.org/10.1079/BJN19930162
  15. Saki, A. A., R. N. Harsini, M. M. Tabatabaei, P. Zamani, M. Haghighat, and H. R. H. Matin. 2011. Thyroid function and egg characteristics of laying hens in response to dietary methionine levels. Afr. J. Agric. Res. 6:4693-4698.
  16. Sangali, C. P., L. D. G. Bruno, R. V. Nunes, A. Rodrigues de Oliveira Neto, P. C. Pozza, T. M. Moraes de Oliveira, R. Frank, and R. Andre Schone. 2014. Bioavailability of different methionine sources for growing broilers. R. Bras. Zootec. 43:140-145. https://doi.org/10.1590/S1516-35982014000300006
  17. Tesseraud, S., A. M. Chagnau, and J. Grizard. 2000. Muscle protein turnover during early development in chickens divergently selected for growth rate. Poult. Sci. 79:1465-1471. https://doi.org/10.1093/ps/79.10.1465
  18. Berhe, E. T. and R. M. Gous. 2008. Effect of dietary protein content on growth, uniformity, and mortality of two commercial broiler strains. S. Afr. J. Anim. Sci. 38:293-302.
  19. Bnouham, M., A. Ziyyat, H. Mekhfi, A. Tahri, and A. Legssyer. 2006. Medicinal plants with potential antidiabetic activity-A review of ten years of herbal medicine research (1990-2000). Int. J. Diabetes Metab. 14:1-25.
  20. Bunchasak, C., T. Sooksridang, and R. Chaiyapit. 2006. Effects of adding methionine hydroxy analogue as methionine source at the commercial requirement recommendation on production performance and evidence of ascites syndrome of male broiler chicks fed corn-soybean based. Int. J. Poult. Sci. 5:744-752. https://doi.org/10.3923/ijps.2006.744.752
  21. Burley, H. K. 2012. Enrichment of methionine from naturally concentrated feedstuffs for use in organic poultry diets. Ph.D. Thesis. The Pennsylvania State University, University Park, PA, USA.
  22. Carew, L. B., J. P. McMurtry, and F. A. Alster. 2003. Effects of methionine deficiencies on plasma levels of thyroid hormones, insulin-like growth factors-I and-II, liver and body weights, and feed intake in growing chickens. Poult. Sci. 82:1932-1938. https://doi.org/10.1093/ps/82.12.1932
  23. Abouelfetouh, A. Y. and N. K. Moussa. 2012. Enhancement of antimicrobial activity of four classes of antibiotics combined with garlic. Asian J. Plant Sci. 11:148-152. https://doi.org/10.3923/ajps.2012.148.152
  24. Aji, S. B., K. Ignatius, A. Y. Ado, J. B. Nahu, A. Abdulkarim, U. Aliyu, M. B. Gambo, M. A. Ibrahim, H. Abubakar, M. M. Bukar, H. M. Imam, and P. T. Numan. 2011. Effects of feeding onion (Allium cepa) and garlic (Allium sativum) on some performance characteristics of broiler chickens. Res. J. Poult. Sci. 4:22-27. https://doi.org/10.3923/rjpscience.2011.22.27
  25. Carew, L. B., K. G. Evarts, and F. A. Alster. 1997. Growth and plasma thyroid hormone concentrations of chicks fed diets deficient in essential amino acids. Poult. Sci. 76:1398-1404. https://doi.org/10.1093/ps/76.10.1398
  26. Danner, E. E. and W. Bessei. 2002. Effectiveness of liquid DLmethionine hydroxy analogue-free acid (DL-MHA-FA) compared to DL-methionine on performance of laying hens. Arch. Geflugelk. 66:97-101.
  27. Ebesunun, M. O., O. O. Popoola, E. O. Agbedana, J. M. Olisekodiaka, J. A. Onuegbu, and A. A. Onyeagala. 2007. The effect of garlic on plasma lipids and lipoproteins in rats fed on high cholesterol enriched diet. Biokemistri 19:53-58.
  28. Enting, H., J. Pos, R. E. Weurding, and A. Veldman. 2005. Starch digestion rate affects broiler performance. Aust. Poult. Sci. Symp. 17:17-20.
  29. Frank, J. W., J. Escobar, H. V. Nguyen, S. C. Jobgen, W. S. Jobgen, T. A. Davis, and G. Wu. 2007. Oral N-carbamylglutamate supplementation increases protein synthesis in skeletal muscle of piglets. J. Nutr. 137:315-319. https://doi.org/10.1093/jn/137.2.315
  30. Gonzales, E., J. Buyse, J. R. Sartori, M. M. Loddi, and E. Decuypere. 1999. Metabolic disturbances in male broilers of different strains. 2. Relationship between the thyroid and somatotropic axes with growth rate and mortality. Poult. Sci. 78:516-521. https://doi.org/10.1093/ps/78.4.516