- Volume 17 Issue 10
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Effects of Tobacco Smoking on the Dorsum of the Tongue and Buccal Epithelium
- Al Shammari, Abdullah Faraj ;
- AL Ibrahim, Ibrahim Khalil ;
- Alaauldeen, Amjad Ibrahim ;
- Merza, Randa Fouad ;
- Ahmed, Hussain Gadelkarim
- Published : 2016.10.01
Objective: The aim of this study was to assess the effects of tobacco smoking on the dorsum of the tongue and buccal epithelium. Methodology: This case control cross-sectional study was conducted with 174 smoking and non-smoking volunteers living in the city of Hail, Northern KSA. Cytological Materials were obtained from buccal mucosa and dorsum of the tongue, and assessed using cytopathological methods. Results: In buccal smears, cytological atypia was observed in 17 out of 101 (16.8%) smoker cases but only 3/73(4.1%) of the controls. For cytological atypia in buccal and tongue smears, the adjusted odd ratio (OR) and the 95% confidence interval (CI) were found to be 4.7 (1.3-16.8), P < 0.016)) and 4.3 (0.93- 20.2), P <0.06)), respectively, in the two sites. Conclusion: Tobacco smoking is a major risk factor for occurrence of cytological atypia, which might subsequently develop into oral precancerous and cancerous lesions. Oral exfoliative cytology is an easy and cheap non-invasive procedure which appears highly suitable for screening populations at risk of developing oral cancer.
Tobacco smoking;buccal mucosa;cytological atypia;tongue;oral
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