- Volume 17 Issue 7
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Expression of the p16 and Ki67 in Cervical Squamous Intraepithelial Lesions and Cancer
- Kanthiya, Kanjana (Department of Obstetrics and Gynecology, Faculty of Medicine Vajira Hospital, Navamindradhiraj University) ;
- Khunnarong, Jakkapan (Department of Obstetrics and Gynecology, Faculty of Medicine Vajira Hospital, Navamindradhiraj University) ;
- Tangjitgamol, Siriwan (Department of Obstetrics and Gynecology, Faculty of Medicine Vajira Hospital, Navamindradhiraj University) ;
- Puripat, Napaporn (Department of Anatomical Pathology, Faculty of Medicine Vajira Hospital, Navamindradhiraj University) ;
- Tanvanich, Sujitra (Department of Anatomical Pathology, Faculty of Medicine Vajira Hospital, Navamindradhiraj University)
- Published : 2016.07.01
Purpose: To evaluate the expression of p16 and Ki67 in cervical intraepithelial neoplasia (CIN) and cancer. Materials and Methods: We performed a immunohistochemical study of p16 and Ki67 in 243 cervical tissues - 53 non-dysplastic lesions, 106 CIN1, 61 CIN2/3 and 23 squamous cell carcinomas. The expression of p16 and Ki67 was interpreted independently by 2 researchers and the sensitivity and specificity to detect clinically significant lesions (
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