- Volume 17 Issue 7
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Applicability of Radioguided Occult Lesion Localization for Non-Palpable Benign Breast Lesions, Comparison with Wire Localization, a Clinical Trial
- Alikhassi, Afsaneh (Cancer Research Center, Cancer Institute of Iran) ;
- Saeed, Farzanefar (Department of Nuclear Medicine, Vali-Asr Hospital, School of Medicine, Tehran University of Medical Sciences) ;
- Abbasi, Mehrshad (Department of Nuclear Medicine, Vali-Asr Hospital, School of Medicine, Tehran University of Medical Sciences) ;
- Omranipour, Ramesh (Division of Surgical Oncology, Department of Surgery, Tehran University of Medical Sciences) ;
- Mahmoodzadeh, Habibollah (Division of Surgical Oncology, Department of Surgery, Tehran University of Medical Sciences) ;
- Najafi, Massoome (Division of Surgical Oncology, Department of Surgery, Tehran University of Medical Sciences) ;
- Gity, Masoumeh (Department of Radiology, Medical Imaging Center, Tehran University of Medical Sciences) ;
- Kheradmand, Ali (Division of Surgical Oncology, Department of Surgery, Tehran University of Medical Sciences)
- Published : 2016.07.01
Background: This study was designed to compare radioguided versus routine wire localization of nonpalpable non-malignant breast lesions in terms of efficacy for complete excision, ease of use, time saving, and cosmetic outcome. Materials and Methods: Patients with non-palpable breast masses and non-malignant core biopsy results who were candidates for complete surgical lumpectomy were enrolled and randomly assigned to radioguided or wire localization groups. Radiologic, surgical, and pathologic data were collected and analyzed to determine the difficulty and duration of each procedure, ease of use, accuracy, and cosmetic outcomes. Results: This prospective randomized study included 60 patients, randomly divided into wire guided localization (WGL) or radioguided occult lesion localization (ROLL) groups. The mean duration of localization under ultrasound guidance was shorter in the ROLL group (14.4 min) than in the WGL group (16.5 min) (p<0.001). The ROLL method was significantly easier for radiologists (p=0.0001). The mean duration of the surgical procedure was 22.6 min (
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