- Volume 17 Issue 5
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Antiproliferative Activity of the Methanolic Extract of Withania Somnifera Leaves from Faifa Mountains, Southwest Saudi Arabia, against Several Human Cancer Cell Lines
- Alfaifi, Mohammad Yahya (Biology Department, Faculty of Science, King Khalid University) ;
- Saleh, Kamel Ahmed (Biology Department, Faculty of Science, King Khalid University) ;
- El-Boushnak, Mohammed Atallah (Biology Department, Faculty of Science, King Khalid University) ;
- Elbehairi, Serag Eldin I (Biology Department, Faculty of Science, King Khalid University) ;
- Alshehri, Mohammed Ali (Biology Department, Faculty of Science, King Khalid University) ;
- Shati, Ali Abdullah (Biology Department, Faculty of Science, King Khalid University)
- Published : 2016.05.01
Cancer represent one of the most serious health problems and major causes of death around the world. Many anticancer drugs in clinical use today are natural products or derived from natural sources. Withania somnifera (L.) Dunal is a small shrub widely distributed in many parts of the world including Saudi Arabia. The antiproliferative activities of the methanolic extract of W. somnifera leaves collected from Faifa mountains, southwest Saudi Arabia against MCF-7, HCT116 and HepH2 cell lines were investigated. The extract showed a strong antiproliferative activity against all cell lines with
Withania somnifera;MCF-7;HCT116;HepG2;Caspase 3;Antiproliferative
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