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Improvement in Sensitivity of Electrochemical Glucose Biosensor Based on CuO/Au@MWCNTs Nanocomposites

CuO/Au@MWCNTs 나노복합재 기반 전기화학적 포도당 바이오센서의 민감도 개선

  • Park, Mi-Seon (Department of Applied Chemistry and Biological Engineering, Chungnam National University) ;
  • Bae, Tae-Sung (Korea Basic Science Institute (KBSI) Jeonju Center) ;
  • Lee, Young-Seak (Department of Applied Chemistry and Biological Engineering, Chungnam National University)
  • 박미선 (충남대학교 대학원 바이오응용화학과) ;
  • 배태성 (한국기초과학지원연구원) ;
  • 이영석 (충남대학교 대학원 바이오응용화학과)
  • Received : 2015.10.28
  • Accepted : 2015.12.10
  • Published : 2016.04.10

Abstract

In this study, CuO was introduced on MWCNTs dispersed with Au nanoparticles to improve the glucose sensing capability of electrochemical biosensors. Nano-cluster shaped CuO was synthesized due to the presence of Au nanoparticle, which affects glucose sensing performance. The biosensor featuring CuO/Au@MWCNTs nanocomposite as an electrode material when 0.1 mole of CuO was synthesized showed the highest sensitivity of $504.1{\mu}A\;mM^{-1}cm^{-2}$, which is 4 times better than that of MWCNTs based biosensors. In addition, it shows a wider linear range from 0 to 10 mM and lower limit of detection (LOD) of 0.008 mM. These results demonstrate that CuO/Au@MWCNTs nanocomposite sensors are superior to other CuO based biosensors which are attributed that the nano-cluster shaped CuO is favorable for the electrochemical reaction with glucose molecules.

Acknowledgement

Supported by : 한국기초과학지원연구원

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