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Biochemical Changes in the Tissue of Mice Irradiated with LINAC

선형가속기를 이용한 방사선조사에서 생쥐조직의 생화학적 변화

  • 최성관 (광주보건대학 방사선과)
  • Received : 2015.10.26
  • Accepted : 2015.11.17
  • Published : 2016.03.28

Abstract

In this study, a linear accelerator (LINAC) through 3 Gy of radiation per body irradiated mice of the small intestine and the liver to produce in order to protect the cells after radiation exposure that caspase (caspase 3 &caspase 9) and NO (nitric oxide), and looked like to know cytokine of IL-6 and TNF-${\alpha}$, the result is as follows. First, caspase 3 & caspase 9 showed a noticeable increase in the radiation group than in the control group both small intestine and liver tissues (P <0.001). Second, NO are both intestine and liver tissue showed a marked increase in the radiation group than in the control group (P <0.001). Third, one of Cytokine IL-6 and TNF-${\alpha}$ showed a significant increase in the irradiated group than the control group both small intestine and liver tissues (P <0.001).

Keywords

Caspase;NO;IL-6;TNF-${\alpha}$;Cytokine

Acknowledgement

Supported by : 광주보건대학교

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