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Psychometric Validation of the Bahasa Malaysia Version of the EORTC QLQ-CR29

  • Magaji, Bello Arkilla (Julius Centre University of Malaya, Department of Social & Preventive Medicine, Faculty of Medicine) ;
  • Moy, Foong Ming (Julius Centre University of Malaya, Department of Social & Preventive Medicine, Faculty of Medicine) ;
  • Roslani, April Camilla (Department of Surgery, Faculty of Medicine, University of Malaya) ;
  • Law, Chee Wei (Department of Surgery, Faculty of Medicine, University of Malaya) ;
  • Raduan, Farhana (Department of Surgery, Universiti Kebangsaan Malaysia Medical Centre) ;
  • Sagap, Ismail (Department of Surgery, Universiti Kebangsaan Malaysia Medical Centre)
  • Published : 2016.01.11

Abstract

Background: This study examined the psychometric properties of the Bahasa Malaysia (BM) version of the European Organization for Research and Treatment of Cancer (EORTC) Colorectal Cancer-specific Quality Of Life Questionnaire (QLQ-CR29). Materials and Methods: We studied 93 patients recruited from University Malaya and Universiti Kebangsaan Medical Centers, Kuala Lumpur, Malaysia using a self-administered method. Tools included QLQ-C30, QLQ-CR29 and Karnofsky Performance Scales (KPS). Statistical analyses included Cronbach's alpha, test-retest correlations, multi-traits scaling and known-groups comparisons. A p vaue ${\leq}0.05$ was considered significant. Results: The internal consistency coefficients for body image, urinary frequency, blood and mucus and stool frequency scales were acceptable (Cronbach's alpha ${\alpha}{\geq}0.65$). However, the coefficients were low for the blood and mucus and stool frequency scales in patients with a stoma bag (${\alpha}=0.46$). Test-retest correlation coefficients were moderate to high (range: r = 0.51 to 1.00) for most of the scales except anxiety, urinary frequency, buttock pain, hair loss, stoma care related problems, and dyspareunia (r ${\leq}0.49$). Convergent and discriminant validities were achieved in all scales. Patients with a stoma reported significantly higher symptoms of blood and mucus in the stool, flatulence, faecal incontinence, sore skin, and embarrassment due to the frequent need to change the stoma bag (p < 0.05) compared to patients without stoma. None of the scales distinguished between patients based on the KPS scores. There were no overlaps between scales in the QLQ-C30 and QLQ-CR29 (r < 0.40). Conclusions: the BM version of the QLQ-CR29 indicated acceptable psychometric properties in most of the scales similar to original validation study. This questionnaire could be used to complement the QLQ-C30 in assessing HRQOL among BM speaking population with colorectal cancer.

Keywords

Colorectal carcinoma;EORTC QLQ-CR29;validity;reliability;Bahasa Malaysia

Acknowledgement

Supported by : Ministry of Higher Education (MOHE)

References

  1. Arraras JI, Suarez J, de la Vega FA, et al (2011). The EORTC quality of life questionnaire for patients with colorectal cancer: EORTC QLQ-CR29 validation study for Spanish patients. Clinical & Translational Oncology, 13, 50-6. https://doi.org/10.1007/s12094-011-0616-y
  2. Calvo O, Oliveros R, Sanchez R (2010). Adaptacion cultural del formulario EORTC QLQ CR-29 para su aplicacion en pacientes con cancer de recto en el Instituto Nacional de Cancerologia de Colombia. Revista Colombiana de Cancerologia, 14, 189-98. https://doi.org/10.1016/S0123-9015(10)70082-2
  3. Farkkila N, Sintonen H, Saarto T, et al (2013). Health-related quality of life in colorectal cancer. Colorectal Dis, 15, 215-22. https://doi.org/10.1111/codi.12143
  4. Hasanah CI (2003). Approaches and methodological as well as interpretative issues in quality of life research in malaysia. Malays J Med Sci, 10, 60-5.
  5. Hung HC, Chien TW, Tsay SL, et al (2013). Patient and clinical variables account for changes in health- related quality of life and symptom burden as treatment outcomes in colorectal cancer: a longitudinal study. Asian Pac J Cancer Prev, 14, 1905-9. https://doi.org/10.7314/APJCP.2013.14.3.1905
  6. Law CC, Lam WWT, Fu YT, et al (2007). The Chinese version of the EORTC colorectal cancer-specific quality of life questionnaire module (QLQ-CR38): Validity and reliability. Psycho-Oncology, 16, 142.
  7. Law CC, Lam WWT, Fu YT, et al (2008). Validation of the chinese version of the EORTC colorectal cancer-specific quality-of-life questionnaire module (QLQ-CR38). Journal of Pain and Symptom Management, 35, 203-13. https://doi.org/10.1016/j.jpainsymman.2007.03.013
  8. Magaji BA, Moy FM, Roslani AC, et al (2014). Descriptive epidemiology of colorectal cancer in University Malaya Medical Centre, 2001 to 2010. Asian Pac J Cancer Prev, 15, 6059-64. https://doi.org/10.7314/APJCP.2014.15.15.6059
  9. Magaji BA, Moy FM, Roslani AC, et al (2012). Health-related quality of life among colorectal cancer patients in Malaysia: a study protocol. BMC Cancer, 12, 384. https://doi.org/10.1186/1471-2407-12-384
  10. Natrah MS, Ezat S, Syed MA, et al (2012). Quality of life in Malaysian colorectal cancer patients: a preliminary result. Asian Pac J Cancer Prev, 13, 957-62. https://doi.org/10.7314/APJCP.2012.13.3.957
  11. Norwati D, Harmy MY, Norhayati MN, et al (2014). Colorectal cancer screening practices of primary care providers: results of a national survey in Malaysia. Asian Pac J Cancer Prev, 15, 2901-4. https://doi.org/10.7314/APJCP.2014.15.6.2901
  12. Nowak W, Tobiasz-Adamczyk B, Brzyski P, et al (2011). Adaptation of quality of life module EORTC QLQ-CR29 for Polish patients with rectal cancer: initial assessment of validity and reliability. Pol Przegl Chir, 83, 502-10.
  13. Peng JJ, Shi DB, Goodman KA, et al (2011). Early results of quality of life for curatively treated rectal cancers in Chinese patients with EORTC QLQ-CR29. Radiation Oncology, 6.
  14. Rotonda C, Conroy T, Mercier M, et al (2008). Validation of the French version of the colorectal-specific quality-of-life questionnaires EORTC QLQ-CR38 and FACT-C. Quality of Life Research, 17, 437-45. https://doi.org/10.1007/s11136-008-9322-9
  15. Shah SA, Neoh HM, Rahim SS, et al (2014). Spatial analysis of colorectal cancer cases in Kuala Lumpur. Asian Pac J Cancer Prev, 15, 1149-54. https://doi.org/10.7314/APJCP.2014.15.3.1149
  16. Silva; JPCMd. EORTC QLQ CR-29 evaluation in 500 patients with colorectal cancer. 2012 Gastrointestinal Cancers Symposium, 2012. J Clin Oncol.
  17. Sprangers MAG, te Velde A, Aaronson NK, et al (1999). The construction and testing of the EORTC colorectal cancerspecific quality of life questionnaire module (QLQ-CR38). European Journal of Cancer, 35, 238-47. https://doi.org/10.1016/S0959-8049(98)00357-8
  18. Thaysen HV, Jess P, Laurberg S, et al (2012). Validation of the Danish version of the disease specific instrument EORTC QLQ-CR38 to assess Health-related quality of life in patients with colorectal cancer. Health and Quality of Life Outcomes, 10.
  19. Tsunoda A, Yasuda N, Nakao K, et al (2008). Validation of the Japanese version of EORTC QLQ-CR38. Quality of Life Research, 17, 317-22. https://doi.org/10.1007/s11136-007-9298-x
  20. Ulaganathan V, Kandiah M, Zalilah MS, et al (2012). Colorectal cancer and its association with the metabolic syndrome: a Malaysian multi-centric case-control study. Asian Pac J Cancer Prev, 13, 3873-7. https://doi.org/10.7314/APJCP.2012.13.8.3873
  21. Wan Puteh SE, Saad NM, Aljunid SM, et al (2013). Quality of life in Malaysian colorectal cancer patients. Asia Pac Psychiatry, 5, 110-7. https://doi.org/10.1111/appy.12055
  22. Whistance RN, Conroy T, Chie W, et al (2009). Clinical and psychometric validation of the EORTC QLQ-CR29 questionnaire module to assess health-related quality of life in patients with colorectal cancer. European Journal of Cancer, 45, 3017-26. https://doi.org/10.1016/j.ejca.2009.08.014

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