- Volume 16 Issue 16
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High Dose Rate Brachytherapy in Two 9 Gy Fractions in the Treatment of Locally Advanced Cervical Cancer - a South Indian Institutional Experience
- Ghosh, Saptarshi (Department of Radiotherapy, GSL Cancer Hospital, GSL Medical College) ;
- Rao, Pamidimukkala Bramhananda (Department of Radiotherapy, GSL Cancer Hospital, GSL Medical College) ;
- Kotne, Sivasankar (Department of Radiotherapy, GSL Cancer Hospital, GSL Medical College)
- Published : 2015.11.04
Background: Although 3D image based brachytherapy is currently the standard of treatment in cervical cancer, most of the centres in developing countries still practice orthogonal intracavitary brachytherapy due to financial constraints. The quest for optimum dose and fractionation schedule in high dose rate (HDR) intracavitary brachytherapy (ICBT) is still ongoing. While the American Brachytherapy Society recommends four to eight fractions of each less than 7.5 Gy, there are some studies demonstrating similar efficacy and comparable toxicity with higher doses per fraction. Objective: To assess the treatment efficacy and late complications of HDR ICBT with 9 Gy per fraction in two fractions. Materials and Methods: This is a prospective institutional study in Southern India carried on from
High dose rate brachytherapy;two fractions;treatment efficacy;late toxicity;cervical cancer
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