- Volume 16 Issue 16
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Declining Incidence of Nasopharyngeal Carcinoma in Brunei Darussalam: a Three Decade Study (1986-2014)
- Chong, Vui Heng (Department of Medicine, RIPAS Hospital) ;
- Telisinghe, Pemsari Upali (Department of Pathology, RIPAS Hospital) ;
- LIM, Edwin (Department of Pathology, RIPAS Hospital) ;
- Abdullah, Muhammad Syafiq (Department of Medicine, RIPAS Hospital) ;
- Idris, Fidah (Department of Oto-Rhino-Laryngology, RIPAS Hospital) ;
- Chong, Chee Fui (Department of Surgery, Bandar Seri Begawan BA)
- Published : 2015.11.04
Background: Nasopharyngeal carcinoma (NPC) is linked to Epstein Barr virus infection and is particularly common in the Far East, particularly among some Chinese groups. Certain ethnicities have been reported to have low incidence of NPC. This study looked at NPC in Brunei Darussalam over a three decade period. Materials and Methods: The cancer registry from 1986 to 2014 maintained by the State Laboratory was retrospectively reviewed. The age standardized rates (ASR) and the age specific incidence rates (ASIR) were calculated. Non NPC tumors were excluded from the study. Results: Altogether, there were a total of 450 NPC cases diagnosed accounting for 4.4% of all total cancer cases over the study period, declining from 10.3% in 1986-1990 to 2.3% in 2011-2014. The most common tumor type was the undifferentiated carcinoma (96.4%). The case characteristics were mean age
Nasopharyngeal neoplasm;incidence;trend;epidemiology;Brunei Darussalam
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