- Volume 16 Issue 16
DOI QR Code
Impact of Omega-3 Fatty Acid Supplements on Gastrointestinal Cancer Patients after Surgery: Beneficial or Useless?
- Zhang, Haibin (Department of Surgical Oncology, First Affiliated hospital, Zhejiang University, School of Medicine) ;
- Zhang, Jing (Department of Surgical Oncology, First Affiliated hospital, Zhejiang University, School of Medicine) ;
- Wang, Haiyong (Department of Surgical Oncology, First Affiliated hospital, Zhejiang University, School of Medicine) ;
- Su, Xingyun (Department of Surgical Oncology, First Affiliated hospital, Zhejiang University, School of Medicine) ;
- Teng, Lisong (Department of Surgical Oncology, First Affiliated hospital, Zhejiang University, School of Medicine)
- Published : 2015.11.04
Omega-3 polyunsaturated fatty acids (
Omega-3 polyunsaturated fatty acids;gastrointestinal cancer;perioperative patients
- Age-Related Eye Disease Study 2 Research G (2013). Lutein + zeaxanthin and omega-3 fatty acids for age-related macular degeneration: the age-related eye disease study 2 (AREDS2) randomized clinical trial. JAMA, 309, 2005-15. https://doi.org/10.1001/jama.2013.4997
- Caglayan K, Oner I, Gunerhan Y, et al (2012). The impact of preoperative immunonutrition and other nutrition models on tumor infiltrative lymphocytes in colorectal cancer patients. Am J Surg, 204, 416-21. https://doi.org/10.1016/j.amjsurg.2011.12.018
- Calder PC (2007). Immunomodulation by omega-3 fatty acids. Prostaglandins Leukot Essent Fatty Acids, 77, 327-35. https://doi.org/10.1016/j.plefa.2007.10.015
- Chapkin RS, Kim W, Lupton JR, et al (2009). Dietary docosahexaenoic and eicosapentaenoic acid: emerging mediators of inflammation. Prostaglandins Leukot Essent Fatty Acids, 81, 187-91. https://doi.org/10.1016/j.plefa.2009.05.010
- Cockbain AJ, Toogood GJ, Hull MA (2012). Omega-3 polyunsaturated fatty acids for the treatment and prevention of colorectal cancer. Gut, 61, 135-49. https://doi.org/10.1136/gut.2010.233718
- de Miranda Torrinhas RS, Santana R, Garcia T, et al (2013). Parenteral fish oil as a pharmacological agent to modulate post-operative immune response: a randomized, doubleblind, and controlled clinical trial in patients with gastrointestinal cancer. Clin Nutr, 32, 503-10. https://doi.org/10.1016/j.clnu.2012.12.008
- Harris WS (2007). Expert opinion: omega-3 fatty acids and bleeding-cause for concern? Am J Cardiol, 99, 44C-6C.
- Jiang ZM, Wilmore DW, Wang XR, et al (2010). Randomized clinical trial of intravenous soybean oil alone versus soybean oil plus fish oil emulsion after gastrointestinal cancer surgery. Br J Surg, 97, 804-9. https://doi.org/10.1002/bjs.6999
- Kar S, Webel R (2012). Fish oil supplementation & coronary artery disease: does it help? Mo Med, 109, 142-5.
- Koch T, Heller AR (2005). Benefits of omega-3 fatty acids in parenteral nutrition. Clinical Nutrition, 17-24.
- Li NN, Zhou Y, Qin XP, et al (2014). Does intravenous fish oil benefit patients post-surgery? A meta-analysis of randomised controlled trials. Clinical Nutrition, 33, 226-39. https://doi.org/10.1016/j.clnu.2013.08.013
- Marano L, Porfidia R, Pezzella M, et al (2013). Clinical and immunological impact of early postoperative enteral immunonutrition after total gastrectomy in gastric cancer patients: a prospective randomized study. Ann Surg Oncol, 20, 3912-8. https://doi.org/10.1245/s10434-013-3088-1
- Miles EA, Calder PC (2012). Influence of marine n-3 polyunsaturated fatty acids on immune function and a systematic review of their effects on clinical outcomes in rheumatoid arthritis. Br J Nutr, 107, 171-84. https://doi.org/10.1017/S0007114512001560
- Nakamura K, Kariyazono H, Komokata T, et al (2005). Influence of preoperative administration of omega-3 fatty acid-enriched supplement on inflammatory and immune responses in patients undergoing major surgery for cancer. Nutrition, 21, 639-49. https://doi.org/10.1016/j.nut.2005.03.001
- Pscheidl E, Schywalsky M, Tschaikowsky K, et al (2000). Fish oil-supplemented parenteral diets normalize splanchnic blood flow and improve killing of translocated bacteria in a low-dose endotoxin rat model. Crit Care Med, 28, 1489-96. https://doi.org/10.1097/00003246-200005000-00039
- Quinn JF, Raman R, Thomas RG, et al (2010). Docosahexaenoic acid supplementation and cognitive decline in Alzheimer disease: a randomized trial. JAMA, 304, 1903-11. https://doi.org/10.1001/jama.2010.1510
- Risk, Prevention Study Collaborative G, Roncaglioni MC, et al (2013). n-3 fatty acids in patients with multiple cardiovascular risk factors. N Engl J Med, 368, 1800-8. https://doi.org/10.1056/NEJMoa1205409
- Rudkowska I (2010). Fish oils for cardiovascular disease: Impact on diabetes. Maturitas, 67, 25-8. https://doi.org/10.1016/j.maturitas.2010.04.012
- Schmidt EB (1997). n-3 fatty acids and the risk of coronary heart disease. Dan Med Bull, 44, 1-22.
- Senkal M, Zumtobel V, Bauer KH, et al (1999). Outcome and cost-effectiveness of perioperative enteral immunonutrition in patients undergoing elective upper gastrointestinal tract surgery: a prospective randomized study. Arch Surg, 134, 1309-16. https://doi.org/10.1001/archsurg.134.12.1309
- Sorensen LS, Thorlacius-Ussing O, Schmidt EB, et al (2014). Randomized clinical trial of perioperative omega-3 fatty acid supplements in elective colorectal cancer surgery. Br J Surg, 101, 33-42. https://doi.org/10.1002/bjs.9361
- Sultan J, Griffin SM, Di Franco F, et al (2012). Randomized clinical trial of omega-3 fatty acid-supplemented enteral nutrition versus standard enteral nutrition in patients undergoing oesophagogastric cancer surgery. Br J Surg, 99, 346-55. https://doi.org/10.1002/bjs.7799
- Tsekos E, Reuter C, Stehle P, et al (2004). Perioperative administration of parenteral fish oil supplements in a routine clinical setting improves patient outcome after major abdominal surgery. Clin Nutr, 23, 325-30. https://doi.org/10.1016/j.clnu.2003.07.008
- Vaughan VC, Hassing MR, Lewandowski PA (2013). Marine polyunsaturated fatty acids and cancer therapy. Br J Cancer, 108, 486-92. https://doi.org/10.1038/bjc.2012.586
- Wei Z, Wang W, Chen J, et al (2014). A prospective, randomized, controlled study of omega-3 fish oil fat emulsion-based parenteral nutrition for patients following surgical resection of gastric tumors. Nutr J, 13, 25. https://doi.org/10.1186/1475-2891-13-25
- Xin W, Wei W, Li X (2012). Effects of fish oil supplementation on cardiac function in chronic heart failure: a meta-analysis of randomised controlled trials. Heart, 98, 1620-5. https://doi.org/10.1136/heartjnl-2012-302119