- Volume 16 Issue 11
DOI QR Code
Risk factors for Opisthorchis viverrini Infection in Nong Khai Province, Thailand
- Chudthaisong, Nittaya (Department of Epidemiology, Faculty of Public Health, Khon Kaen University) ;
- Promthet, Supannee (Department of Epidemiology, Faculty of Public Health, Khon Kaen University) ;
- Bradshaw, Peter (Department of Epidemiology, Faculty of Public Health, Khon Kaen University)
- Published : 2015.06.26
Background: Opisthorchis viverrini (OV) infection is the main risk factor for cholangiocarcinoma and is often found in Northeastern Thailand. The prevalence of OV infection and the incidence of cholangiocarcinoma are major public health problems in this region. Objectives: The objectives of this study were to identify factors associated with OV infection among people in Nong Khai Province in order to develop a prevention programme in the community. Materials and Methods: The data were collected in July 2013. Stool specimens were examined for intestinal parasites within hours after collection using a normal saline wet preparation and the modified Kato-Katz technique. A case-control study was conducted to collect information about demographic data, the habit of eating unsafely prepared fish, the safe disposal of waste food, and the practice of defaecating in fields. Structured questionnaires were used to interview 351 participants (117 cases and 234 controls) in a random selection of 30 villages across Nong Khai Province. Multiple logistic regression was used to identify risk factors for OV infection. Results: In the multivariate analysis, the results showed that the factors which had a statistically significant association with OV infection were the habit of consuming unsafely prepared fish (
Opisthorchis viverrini;risk factor;Nong Khai, Thailand
Supported by : Khon Kaen University
- Forrer A, Sayasone S, Vounatsou P, et al (2012). Spatial Distribution of, and Risk Factors for, Opisthorchis viverrini Infection in Southern Lao PDR. PLoS Negl Trop Dis, 6, 1-12.
- Saengsawang P, Promthet S, Bradshaw P (2013). Infection with Opisthorchis viverrini and use of praziquantel among a working-age population in Northeast Thailand. Asian Pac J Cancer Prev, 14, 2963-6. https://doi.org/10.7314/APJCP.2013.14.5.2963
- Sithithaworn P, Andrews RH, Nguyen VD, et al (2012). The current status of opisthorchiasis and clonorchiasis in the Mekong Basin. Parasitol Int, 61, 10-6. https://doi.org/10.1016/j.parint.2011.08.014
- Songserm N, Promthet S,Wiangnon S, Sithithaworn P (2012). Prevalence and co-infection of intestinal parasites among Thai rural residents at high-risk of developing cholangiocarcinoma: a cross-sectional study in a prospective cohort study. Asian Pac J Cancer Prev, 13, 6175-9. https://doi.org/10.7314/APJCP.2012.13.12.6175
- Sripa B, Brindley PJ, Mulvenna J, et al (2012). The tumorigenic liver fluke Opisthorchis viverrini-multiple pathways to cancer. Trends Parasitol, 28, 395-407. https://doi.org/10.1016/j.pt.2012.07.006
- StataCorp LP (2007). Stata Release 10: User's guide. College Station TX: Stata Press.
- Thaewnongiew K, Singthong S, Kutchamart S, et al (2014). Prevalence and risk factors for Opisthorchis viverrini infections in upper northeast Thailand. Asian Pac J Cancer Prev, 15, 6609-12. https://doi.org/10.7314/APJCP.2014.15.16.6609
- Upatham ES, Viyanant V, Brockelman WY, et al (1988). Opisthorchis viverrini in an endemic northeast Thai community after chemotherapy. In J Parasitol, 18, 643-9.
- Review and Current Status of Opisthorchis viverrini Infection at the Community Level in Thailand vol.16, pp.16, 2015, https://doi.org/10.7314/APJCP.2015.16.16.6825
- Detection of the Carcinogenic Liver Fluke Opisthorchis viverrini Using a Mini Parasep SF Faecal Parasite Concentrator vol.17, pp.1, 2016, https://doi.org/10.7314/APJCP.2016.17.1.373
- Prevalence and Factors Associated with Opisthorchis viverrini Infection in Khammouane Province, Lao PDR vol.17, pp.3, 2016, https://doi.org/10.7314/APJCP.2016.17.3.1589