A Convergence Study on effectiveness of contrast agent reduction by normal saline solution dilution in the computed tomography of arteries of lower limb

하지동맥 전산화단층촬영 검사 시 생리식염수 희석을 통한 조영제 사용량 감소의 융복합 효용성 연구

  • Kim, Sang-Hyun (Dept. of Radiology, Seoul National University Hospital, Dept. of Radiological Science, Eulji University)
  • 김상현 (서울대학교병원 영상의학과, 을지대학교 방사선학과)
  • Received : 2015.07.18
  • Accepted : 2015.09.20
  • Published : 2015.09.28


This convergence study analyzed the effectiveness of contrast agent reduction by normal saline solution dilution in the computed tomography of arteries of lower limb. 48 patients of 125 cc contrast agent and 30 patients of the same amount divided at a ratio of 7:3 for the contrast agent and normal saline solution were studied. The average attenuation coefficient(HU) and signal to noise ratio(SNR) of abdominal aorta, femoral artery, popliteal artery and posterior tibial artery at each image were evaluated quantitatively and the four criteria in the five point scale was conducted qualitatively by two radiologists and four radiological technologists. In the quantitative evaluation, both HU and SNR had high average score before dilation but there were no statistical significance by independent t-test(p>0.05). In the qualitative evaluation, there were a little differences in the average scores between 4.86~4.77 of original contrast agent and 4.83~4.67 of dilated contrast agent but there were no statistical significance(p>0.05). In the computed tomography of arteries of lower limb, the dilated contrast agent doesn't influence image quality and reduces overall contrast agent and lowers iodine content per unit of molecular therefore will contribute to decrease side effect of contrast agent.


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