DOI QR코드

DOI QR Code

Systematic Analysis on the GSTM1 Null Phenotype and Prostate Cancer Risk in Chinese People

  • Shi, Jing (Department of Urology, Tangshan Gongren hospital, Hebei Medical University) ;
  • Zhuang, Yan (Department of Neurology, Tangshan Gongren hospital, Hebei Medical University) ;
  • Liu, Yan (Department of Urology, Tangshan Gongren hospital, Hebei Medical University) ;
  • Yan, Cheng-Quan (Department of Urology, Tangshan Gongren hospital, Hebei Medical University) ;
  • Liu, Xian-Kui (Department of Urology, No.1 Hospital) ;
  • Zhang, Ying (Experiment Technology Center, China Medical University)
  • Published : 2015.03.18

Abstract

Objective: Glutathione S-transferase M 1 (GSTM1) is implicated as a risk factor for prostate cancer. However, this issue is not clear in Chinese population. This systemic analysis was conducted to evaluate the effect of GSTM1 null genotypes on prostate cancer risk in Chinese. Methods: Published studies investigating the associations between GSTM1 null genotypes and the risk of prostate cancer in China were identified by using a predefined search strategy. Main statisticals were pooled and estimated according to the primarily reported data. Results: The prevalence of the GSTM1 null genotype was higher in prostate cancer patients than in controls, with significance. Conclusion: The GSTM1 null genotypes is associated with increased risk of prostate cancer in Chinese.

Keywords

Genetic polymorphism;GSTM1;prostate cancer;Chinese

References

  1. Chan R, Lok K, Woo J (2009). Prostate cancer and vegetable consumption. Mol Nutr Food Res, 53, 201-16. https://doi.org/10.1002/mnfr.200800113
  2. Chen SH, Wu WJ, Tu HP, et al (2013). Glutathione S-transferase expression in upper urinary tract urothelial carcinomas: a Taiwan study. Asian Pac J Cancer Prev, 14, 6475-9. https://doi.org/10.7314/APJCP.2013.14.11.6475
  3. Choubey VK, Sankhwar SN, Tewari R, et al (2013). Null genotypes at the GSTM1 and GSTT1 genes and the risk of benign prostatic hyperplasia: a case-control study and a meta-analysis. Prostate, 73, 146-52. https://doi.org/10.1002/pros.22549
  4. Du LB, Li HZ, Wang XH, et al (2014). Analysis of cancer incidence in Zhejiang cancer registry in China during 2000 to 2009. Asian Pac J Cancer Prev, 15, 5839-43. https://doi.org/10.7314/APJCP.2014.15.14.5839
  5. Gallagher RP, Fleshner N (1998). Prostate cancer: 3 Individual risk factors. CMAJ, 159, 807-13.
  6. Guan TY, Li M, Na YQ (2005). Polymorphism of metabolic gene and genetic susceptibility to prostate cancer. Zhonghua Wai Ke Za Zhi, 43, 1467-70.
  7. Hayes JD, Flanagan JU, Jowsey IR (2005). Glutathione transferases. Annu Rev Pharmacol Toxicol, 45, 51-88. https://doi.org/10.1146/annurev.pharmtox.45.120403.095857
  8. Hayes JD, Strange RC (2000). Glutathione S-transferase polymorphisms and their biological consequences. Pharmacology, 61, 154-66. https://doi.org/10.1159/000028396
  9. Han SJ, Zhang SW, Chen WQ, et al (2013). Analysis of the status and trends of prostate cancer incidence in China. Chin Clin Oncol, 18, 330-4.
  10. Hassler S, Sjolander P, Gronberg H, et al (2008). Cancer in the Sami population of Sweden in relation to lifestyle and genetic factors. Eur J Epidemiol, 23, 273-80. https://doi.org/10.1007/s10654-008-9232-8
  11. Hu ZH, Lin YW, Xu X, et al (2013). Genetic polymorphisms of glutathione S-transferase M1 and prostate cancer risk in Asians: a meta-analysis of 18 studies. Asian Pac J Cancer Prev, 14, 393-8. https://doi.org/10.7314/APJCP.2013.14.1.393
  12. Jemal A, Bray F, Center MM, et al (2011). Global cancer statistics. CA Cancer J Clin, 61, 69-90. https://doi.org/10.3322/caac.20107
  13. Kumar V, Yadav CS, Datta SK, et al (2011). Association of GSTM1 and GSTT1 polymorphism with lipid peroxidation in benign prostate hyperplasia and prostate cancer: a pilot study. Dis Markers, 30, 163-9. https://doi.org/10.1155/2011/624961
  14. Leitzmann MF, Rohrmann S (2012). Risk factors for the onset of prostatic cancer: age, location, and behavioral correlates. Clin Epidemiol, 4, 1-11.
  15. Li Y, Ma WJ, Qi BK, et al (2014). Blending of soybean oil with selected vegetable oils: impact on oxidative stability and radical scavenging activity. Asian Pac J Cancer Prev, 15, 2583-9. https://doi.org/10.7314/APJCP.2014.15.6.2583
  16. Li M, Guan TY, Li Y, et al (2008). Polymorphisms of GSTM1 and CYP1A1 genes and their genetic susceptibility to prostate cancer in Chinese men. Chin Med J, 121, 305-8.
  17. Mo Z, Gao Y, Cao Y, et al (2009) An updating meta-analysis of the GSTM1, GSTT1, and GSTP1 polymorphisms and prostate cancer: a HuGE review. Prostate, 696, 662-88.
  18. Parent ME1, Rousseau MC, El-Zein M, et al (2011). Occupational and recreational physical activity during adult life and the risk of cancer among men. Cancer Epidemiol, 35, 151-9. https://doi.org/10.1016/j.canep.2010.09.004
  19. Sharma R, Yang Y, Sharma A, et al (2004). Antioxidant role of glutathione s-transferases: protection against oxidant toxicity and regulation of stress-mediated apoptosis. Antioxid Redox Signal, 6, 289-300. https://doi.org/10.1089/152308604322899350
  20. Thakur VS, Gupta K, Gupta S (2012). . Green tea polyphenols causes cell cycle arrest and apoptosis in prostate cancer cells by suppressing class I histone deacetylases. Carcinogenesis, 33, 377-84. https://doi.org/10.1093/carcin/bgr277
  21. Wang YL, Jiang J, Wang LF, et al (2005). Polymorphisms of glutathione-S-transferase genes GSTM1 and GSTT1 and prostate cancer risk in Chinese population. Acta Academiae Medicinae Militaris Tertiae, 27, 1039-41.
  22. Yang L, Pascal M, Wu XH (2013). Review of selenium and prostate cancer prevention. Asian Pac J Cancer Prev, 14, 2181-4. https://doi.org/10.7314/APJCP.2013.14.4.2181
  23. Yang J, Wu HF, Zhang W, et al (2006). Polymorphisms of metabolic enzyme genes, living habits and prostate cancer susceptibility. Front Biosci, 11, 2052-60.