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Nanoparticles Promise New Methods to Boost Oncology Outcomes in Breast Cancer

  • Islamian, Jalil Pirayesh (Department of Medical Physics, Faculty of Medicine, Tabriz University of Medical Sciences) ;
  • Hatamian, Milad (Department of Medical Physics, Faculty of Medicine, Tabriz University of Medical Sciences) ;
  • Rashidi, Mohammad Reza (Department of Medicinal Chemistry, Faculty of Pharmacy, Tabriz University of Medical Sciences)
  • Published : 2015.03.18

Abstract

Different types of treatment are available for patients with breast cancer, the most being radiotherapy, chemotherapy, hormonal therapy and combination therapy. Recently, nanoparticles have been emerging as promising agents for cancer therapy and are being investigated as contrast agents, drug carriers, radiosensitizers and also for hyperthermia effects. In this review the focus is on approaches for targeted treatment of breast cancer by combining nanoparticles, chemodrugs and radiation. The availble data suggest the possibility of increased roles for combined therapy, particularly by reducing the dose of each treatment modality, and consequently minimizing related side effects.

Keywords

Breast cancer;chemodrugs;doxorubicin;nanoparticles;radiation therapy;2-deoxy-D-glucose

Acknowledgement

Supported by : Tabriz University of Medical Sciences

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