- Volume 16 Issue 7
DOI QR Code
Anti-proliferation Effects of Isorhamnetin on Lung Cancer Cells in Vitro and in Vivo
- Li, Qiong (School of Preclinical and Forensic Medicine, Sichuan University) ;
- Ren, Fu-Qiang (Department of Thoracic Surgery, The Third People's Hospital of Chengdu) ;
- Yang, Chun-Lei (Life Science College, Sichuan University) ;
- Zhou, Li-Ming (School of Preclinical and Forensic Medicine, Sichuan University) ;
- Liu, Yan-You (School of Preclinical and Forensic Medicine, Sichuan University) ;
- Xiao, Jing (School of Preclinical and Forensic Medicine, Sichuan University) ;
- Zhu, Ling (School of Preclinical and Forensic Medicine, Sichuan University) ;
- Wang, Zhen-Grong (School of Preclinical and Forensic Medicine, Sichuan University)
- Published : 2015.04.14
Background: Isorhamnetin (Iso), a novel and essential monomer derived from total flavones of Hippophae rhamnoides that has long been used as a traditional Chinese medicine for angina pectoris and acute myocardial infarction, has also shown a spectrum of antitumor activity. However, little is known about the mechanisms of action Iso on cancer cells. Objectives: To investigate the effects of Iso on A549 lung cancer cells and underlying mechanisms. Materials and Methods: A549 cells were treated with
Isorhamnetin;apoptosis;A549;Lewis lung carcinoma;flavones
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