Asian Pacific Journal of Cancer Prevention
- Volume 16 Issue 9
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- Pages.3779-3783
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- 2015
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- 1513-7368(pISSN)
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- 1513-7368(eISSN)
DOI QR Code
Effect of Sesamin on Apoptosis and Cell Cycle Arrest in Human Breast Cancer MCF-7 Cells
- Siao, An-Ci (Department of Life Sciences, National Central University) ;
- Hou, Chien-Wei (Department of Biotechnology and Pharmaceutical Technology, Yuanpei University) ;
- Kao, Yung-Hsi (Department of Life Sciences, National Central University) ;
- Jeng, Kee-Ching (Department of Pharmacy, Tungs' Taichung MetroHarbor Hospital)
- Published : 2015.05.18
Abstract
Dietary prevention has been known to reduce breast cancer risk. Sesamin is one of the major components in sesame seeds and has been widely studied and proven to have anti-proliferation and anti-angiogenic effects on cancer cells. In this study, the influence of sesamin was tested in the human breast cancer MCF-7 cell line for cell viability (MTT assay) and cell cycling (flow cytometry). Results showed that sesamin dose-dependently (1, 10 and
Keywords
Sesamin;breast cancer;apoptosis;cell cycle
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