- Volume 16 Issue 10
DOI QR Code
Dietary Resistant Starch Contained Foods and Breast Cancer Risk: a Case-Control Study in Northwest of Iran
- Tajaddini, Aynaz (Nutrition Research Center, Tabriz University of Medical Sciences) ;
- Pourzand, Ali (Department of General Surgery, Faculty of Medicine, Tabriz University of Medical Sciences) ;
- Sanaat, Zohreh (Hematology and Oncology Research Center, Tabriz University of Medical Sciences) ;
- Pirouzpanah, Saeed (Department of Biochemistry and Dietetics, Faculty of Nutrition, Tabriz University of Medical Sciences)
- Published : 2015.06.03
Background: A protective effect of resistant starch (RS) containing foods on carcinogenesis has been shown from several lines of experimental evidence for gastrointestinal cancers. Therefore, we aimed to investigate the association between RS contained foods and breast cancer (BC) risk in a hospital-based, age- and origin-matched, case-control study. Materials and Methods: A validated, semi-quantitative, food frequency questionnaire (FFQ) was completed by 306 women newly diagnosed with BC aged 25 to 65 years, and 309 healthy women as matched controls. Odds ratios (ORs) and 95% confidence intervals (95%CI) were estimated using conditional logistic regression models. Results: Reduced BC risk was associated with the highest tertile of whole-wheat bread and boiled potato consumption with adjusted ORs at 0.34 (95%CI: 0.19-0.59) and 0.61 (95%CI: 0.37-0.99), respectively. Among consumers of whole-wheat bread, the protective role of cereals remained relatively apparent at higher intakes level of fiber rich breads at adjusted models (OR=0.53, 95%CI: 0.28-1.01). Moreover, high intake of legumes was found out to be a significant protective dietary factor against risk of BC development with an OR of 0.01 (95%CI: 0.03-0.13). However, consumption of white bread and biscuits was positively related to BC risk. Conclusions: Our results show that certain RS containing foods, in particular whole wheat bread, legumes and boiled potato may reduce BC risk, whereas higher intake of white bread and biscuits may be related to increased BC risk.
Breast cancer;prebiotics;fiber;resistant starch;whole grains;refined grains
- Adebamowo C, Cho E, Sampson L, et al (2005). Dietary flavonols and flavonol-rich foods intake and the risk of breast cancer. Int J Cancer, 114, 628-33. https://doi.org/10.1002/ijc.20741
- Al-Fatlawi AA, Al-Fatlawi AA, Irshad M, et al (2014). Rice bran phytic acid induced apoptosis through regulation of Bcl-2/Bax and p53 genes in HepG2 human hepatocellular carcinoma cells. Asian Pac J Cancer Prev, 15, 3731-6. https://doi.org/10.7314/APJCP.2014.15.8.3731
- Aune D, Chan D, Lau R, et al (2011). Dietary fibre, whole grains, and risk of colorectal cancer: systematic review and dose-response meta-analysis of prospective studies. BMJ, 343, d6617. https://doi.org/10.1136/bmj.d6617
- Bahadoran Z, Karimi Z, Houshiar-rad A, et al (2013). Dietary phytochemical index and the risk of breast cancer: a case control study in a population of Iranian women. Asian Pac J Cancer Prev, 14, 2747-51. https://doi.org/10.7314/APJCP.2013.14.5.2747
- Block G, Hartman A, Dresser C, et al (1986). A data-based approach to diet questionnaire design and testing. Am J Epidemiol, 124, 453-69. https://doi.org/10.1093/oxfordjournals.aje.a114416
- Brouns F, Kettlitz B, Arrigoni E (2002). Resistant starch and the butyrate revolution. Trends Food Sci Tech, 13, 251-61. https://doi.org/10.1016/S0924-2244(02)00131-0
- Chatenoud L, Tavani A, La Vecchia C, et al (1998). Whole grain food intake and cancer risk. Int J Cancer, 77, 24-8. https://doi.org/10.1002/(SICI)1097-0215(19980703)77:1<24::AID-IJC5>3.0.CO;2-1
- Cummings JH, Englyst HN (1995). Gastrointestinal effects of food carbohydrates. Am J Clin Nutr, 61, 938-45. https://doi.org/10.1093/ajcn/61.4.938S
- Dong J-Y, He K, Wang P, et al (2012). Dietary fiber intake and risk of breast cancer: a meta-analysis of prospective cohort studies. Am J Clin Nutr, 94, 900-5.
- Dos Santos Silva I, Mangtani P, McCormack V, et al (2002). Lifelong vegetarianism and risk of breast cancer: a population-based case-control study among South Asian migrant women living in England. Int J Cancer, 99, 238-44. https://doi.org/10.1002/ijc.10300
- Egeberg R, Olsen A, Christensen J, et al (2011). Intake of wholegrain products and risk of prostate cancer among men in the Danish diet, cancer and health cohort study. Cancer Causes Control, 22, 1133-9. https://doi.org/10.1007/s10552-011-9789-5
- Fontana L, Klein S, Holloszy J (2006). Long-term low-protein, low-calorie diet and endurance exercise modulate metabolic factors associated with cancer risk. Am J Clin Nutr, 84, 1456-62. https://doi.org/10.1093/ajcn/84.6.1456
- Franceschi S, La Vecchia C, Russo A, et al (1997). Low-risk diet for breast cancer in Italy. Cancer Epidemiol Biomarkers Prev, 6, 875-9.
- Ghaffarpour M, Housyar-Rad A, Kianfar T (1999). The manual for household measures, cooking yields factors and edible portion of food. Tehran, Keshavarzi Press.
- Hirose K, Tajima K, Hamajima N, et al (1995). A larg-scale, hospital-based case-control study of risk factors of breast cancer according to menopausal status. Cancer Sci, 86, 146-54.
- Jacobs D, Marquart L, Salvin J, et al (1998a). Whole-grain intake and cancer: an expanded review and metaanalysis. Nutr Cancer, 30, 85-96. https://doi.org/10.1080/01635589809514647
- Jacobs D, Meyer K, Kushi L, et al (1998b). Whole grain intake may reduce the risk od ischemic heart disease death in postmenopausal women: the Iowa Women's Health Study. Am J Clin Nutr, 68, 248-57. https://doi.org/10.1093/ajcn/68.2.248
- Kaaks R, Lukanova A (2001). Energy balance and cancer: the role of insulin and insulin-like growth factor-I. Proc Nutr Soc, 60, 91-106. https://doi.org/10.1079/PNS200070
- Kasum C, Nicodemus K, Harnack L, et al (2001). Whole grain intake and incident endometrial cancer: the Iowa women's health study. Nutr Cancer, 39, 180-6. https://doi.org/10.1207/S15327914nc392_4
- Kleessen B, Sykura B, Zunft HJ, et al (1997). Effects of inulin and lactose on fecal microflora, microbial activity, and bowel habit in elderly constipated persons. Am J Clin Nutr, 65, 1397-402. https://doi.org/10.1093/ajcn/65.5.1397
- Kruk J (2014). Association between vegetable, fruit and carbohydrate intake and breast cancer risk in relation to physical activity. Asian Pac J Cancer Prev, 15, 4429-36. https://doi.org/10.7314/APJCP.2014.15.11.4429
- Kyro C, Skeie G, Loft S, et al (2013). Intake of whole grains from different cereal and food sources and incidence of colorectal cancer in the Scandinavian HELGA cohort. Cancer Causes Control, 24, 1363-74. https://doi.org/10.1007/s10552-013-0215-z
- Levi F, Francheschi S, Negri E, et al (1993). Dietary factors and the risk of endometrial cancer. Cancer, 71, 3575-81. https://doi.org/10.1002/1097-0142(19930601)71:11<3575::AID-CNCR2820711119>3.0.CO;2-0
- Lissowska J, Gail M, Pee D, et al (2004). Diet and stomach cancer risk in Warsaw, Poland. Nutr Cancer, 48, 149-59. https://doi.org/10.1207/s15327914nc4802_4
- Nicodemus K, Jacobs Jr D, Folsom A (2001). Whole and refined grain intake and risk of incident postmenopausal breast cancer (United States). Cancer Causes Control, 12, 917-25. https://doi.org/10.1023/A:1013746719385
- Nimptsch K, Kenfield S, Jensen M, et al (2011). Dietary glycemic index, glycemic load, insulin index, fiber and whole-grain intake in relation to risk of prostate cancer. Cancer Causes Control, 22, 51-61. https://doi.org/10.1007/s10552-010-9671-x
- Ollberding N, Lim U, Wilkens L, et al (2012). Legume, soy, tofu, and isoflavone intake and endometrial cancer risk in postmenopausal women in the multiethnic cohort study. J Natl Cancer Inst, 104, 67-76. https://doi.org/10.1093/jnci/djr475
- Paturi G, Nyanhanda T, Butts C, et al (2012). Effects of potato fiber and potato-resistant starch on biomarkers of colonic health in rats fed diets containing red meat. J Food Sci, 77, 216-23.
- Pirouzpanah S, Taleban F, Sabour S, et al (2012). Validation of food frequency questionnaire to assess folate intake status in breast cancer patients. Razi J Med Sci, 18, 31-41.
- Pirouzpanah S, Taleban FA, Atri M, et al (2010). The effect of modifiable potentials on hypermethylation status of retinoic acid receptor-beta2 and estrogen receptor-alpha genes in primary breast cancer. Cancer Causes Control, 21, 2101-11. https://doi.org/10.1007/s10552-010-9629-z
- Pirouzpanah S, Taleban FA, Mehdipour P, et al (2014). Plasma total homocysteine level in association with folate, pyridoxine, and cobalamin status among Iranian primary breast cancer patients. Nutr Cancer, 66, 1097-108. https://doi.org/10.1080/01635581.2014.948213
- Pirouzpanah S, Taleban FA, Mehdipour P, et al (2013). The biomarker-based validity of a food frequency questionnaire to assess the intake status of folate, pyridoxine and cobalamin among Iranian primary breast cancer patients. Eur J Clin Nutr, 68, 1-8.
- Pirouzpanah S, Taleban FA, Mehdipour P, et al (2014). The biomarker-based validity of a food frequency questionnaire to assess the intake status of folate, pyridoxine and cobalamin among Iranian primary breast cancer patients. Eur J Clin Nutr, 68, 316-23. https://doi.org/10.1038/ejcn.2013.209
- Roy CC, Kien CL, Bouthillier L, et al (2006). Short-chain fatty acids: ready for prime time? Nutr Clin Pract, 21, 351-66. https://doi.org/10.1177/0115426506021004351
- Salvin J (2004). Whole grain and human health. Nutr Res Rev, 17, 99-110. https://doi.org/10.1079/NRR200374
- Satia-Abouta J, Galanko J, Martin C, et al (2004). Food groups and colon cancer risk in African-Americans and Caucasians. Int J Cancer, 109, 728-36. https://doi.org/10.1002/ijc.20044
- Shannon J, Ray R, Wu C, et al (2005). Food and botanical groupings and risk of breast cancer: a case-control study in Shanghai, China. Cancer Epidemiol Biomarkers Prev, 14, 81-90.
- Slattery M, Curtin K, Edwards S, et al (2004). Plant foods, fiber, and rectal cancer. Am J Clin Nutr, 79, 274-81. https://doi.org/10.1093/ajcn/79.2.274
- Sulaiman S, Shahril MR, Wafa SW, et al (2014). Dietary carbohydrate, fiber and sugar and risk of breast cancer according to menopausal status in Malaysia. Asian Pac J Cancer Prev, 15, 5959-64. https://doi.org/10.7314/APJCP.2014.15.14.5959
- Tao M, Xu W, Zheng W, et al (2005). A case-control study in Shanghai of fruit and vegetable intake and endometrial cancer. Br J Cancer, 92, 2059-64. https://doi.org/10.1038/sj.bjc.6602609
- Tharanathan RN, Mahadevamma S (2003). Grain legumes: a boon to human nutrition. Trends Food Sci Tech, 14, 507-18. https://doi.org/10.1016/j.tifs.2003.07.002
- Topping DL, Anthony MF, Bird F (2003). Resistant starch as prebiotic and synbiotic: state of the art. P Nutr Soc, 62, 171-6. https://doi.org/10.1079/PNS2002224
- Topping DL, Clifton PM (2001). Short-chain fatty acids and human colonic function: roles of resistant starch and nonstarch polysaccharides. Physiol Rev, 81, 1031-64. https://doi.org/10.1152/physrev.2001.81.3.1031
- Turkoz FP, Celenkoglu G, Dogu GG, et al (2011). Risk factors of nasopharyngeal carcinoma in Turkey-an epidemiological survey of the Anatolian society of medical oncology. Asian Pac J Cancer Prev, 12, 3017-21.
- Wen W, Shu X, Li H, et al (2009). Dietary carbohydrates, fiber, and breast cancer risk in Chinese women. Am J Clin Nutr, 89, 283-9. https://doi.org/10.3945/ajcn.2008.26356
- Witte J, Ursin G, Siemiatycki J, et al (1997). Diet and premenopausal bilateral breast cancer: a case-control study. Breast Cancer Res Treat, 42, 243-51. https://doi.org/10.1023/A:1005710211184
- Woo HD, Park KS, Shin A, et al (2013). Glycemic index and glycemic load dietary patterns and the associated risk of breast cancer: a case-control study. Asian Pac J Cancer Prev, 14, 5193-8. https://doi.org/10.7314/APJCP.2013.14.9.5193
- Yaw YH, Shariff ZM, Kandiah M, et al (2014). Diet and physical activity in relation to weight change among breast cancer patients. Asian Pac J Cancer Prev, 15, 39-44. https://doi.org/10.7314/APJCP.2014.15.1.39
- Zaineddin AK, Buck K, Vrieling A, et al (2012). The association between dietary lignans, phytoestrogen-rich foods, and fiber intake and postmenopausal breast cancer risk: a German case-control study. Nutr Cancer, 64, 652-65. https://doi.org/10.1080/01635581.2012.683227
- Zhang Y, Wang Y, Zheng B, et al (2013 ). The in vitro effects of retrograded starch (resistant starch type 3) from lotus seed starch on the proliferation of Bifidobacterium adolescentis. Food Funct, 4, 1609-16. https://doi.org/10.1039/c3fo60206k
- Zhu Q, Jin Z, Wu W, et al (2014). Analysis of the intestinal lumen microbiota in an animal model of colorectal cancer. PLoS One, 9, 90849. https://doi.org/10.1371/journal.pone.0090849
- Effects of Fresh Yellow Onion Consumption on CEA, CA125 and Hepatic Enzymes in Breast Cancer Patients: A Double-Blind Randomized Controlled Clinical Trial vol.16, pp.17, 2015, https://doi.org/10.7314/APJCP.2015.16.17.7517
- Vegetables and Risk of Breast Cancer: A Hospital-Based Matched Case-Control Study vol.19, pp.3, 2016, https://doi.org/10.4048/jbc.2016.19.3.292
- Engineered Resistant-Starch (ERS) Diet Shapes Colon Microbiota Profile in Parallel with the Retardation of Tumor Growth in In Vitro and In Vivo Pancreatic Cancer Models vol.9, pp.4, 2017, https://doi.org/10.3390/nu9040331
- Association between whole grain intake and breast cancer risk: a systematic review and meta-analysis of observational studies vol.17, pp.1, 2018, https://doi.org/10.1186/s12937-018-0394-2
- Health and Nutrition Studies Related to Cereal Biodiversity: A Participatory Multi-Actor Literature Review Approach vol.10, pp.9, 2018, https://doi.org/10.3390/nu10091207
- Rising Cancer Incidence and Role of the Evolving Diet in Kenya pp.1532-7914, 2019, https://doi.org/10.1080/01635581.2018.1542010