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Differences in Clinical and Laboratory Findings between Group D and Non-Group D Non-Typhoidal Salmonella Gastroenteritis in Children

  • Park, Heung Keun (Department of Pediatrics, Gyeongsang Institute of Health Science, Gyeongsang National University School of Medicine) ;
  • Rhie, Kyuyol (Department of Pediatrics, Gyeongsang Institute of Health Science, Gyeongsang National University School of Medicine) ;
  • Yeom, Jung Sook (Department of Pediatrics, Gyeongsang Institute of Health Science, Gyeongsang National University School of Medicine) ;
  • Park, Ji Sook (Department of Pediatrics, Gyeongsang Institute of Health Science, Gyeongsang National University School of Medicine) ;
  • Park, Eun Sil (Department of Pediatrics, Gyeongsang Institute of Health Science, Gyeongsang National University School of Medicine) ;
  • Seo, Ji-Hyun (Department of Pediatrics, Gyeongsang Institute of Health Science, Gyeongsang National University School of Medicine) ;
  • Lim, Jae Young (Department of Pediatrics, Gyeongsang Institute of Health Science, Gyeongsang National University School of Medicine) ;
  • Park, Chan-Hoo (Department of Pediatrics, Gyeongsang Institute of Health Science, Gyeongsang National University School of Medicine) ;
  • Woo, Hyang-Ok (Department of Pediatrics, Gyeongsang Institute of Health Science, Gyeongsang National University School of Medicine) ;
  • Youn, Hee-Shang (Department of Pediatrics, Gyeongsang Institute of Health Science, Gyeongsang National University School of Medicine) ;
  • Kang, Ki Ryeon (Department of Biochemistry, Gyeongsang Institute of Health Science, Gyeongsang National University School of Medicine) ;
  • Park, Jung Je (Department of Otolaryngology, Gyeongsang Institute of Health Science, Gyeongsang National University School of Medicine)
  • Received : 2015.01.21
  • Accepted : 2015.03.30
  • Published : 2015.06.30

Abstract

Purpose: To investigate the differences in clinical features and laboratory findings between group D and non-group D non-typhoidal Salmonella (NTS) gastroenteritis in children. Methods: A retrospective chart review of children diagnosed with NTS confirmed by culture study was performed. The clinical features and laboratory findings of group D and non-group D NTS were compared. Results: From 2003 to 2012, 75 cases were diagnosed as NTS at our center. The number of group D and non-group D patients was 45 and 30, respectively. The mean age was higher in group D than in non-group D patients (5.1 years vs. 3.4 years, p=0.038). Headaches were more frequently observed (p=0.046) and hematochezia was less frequently observed (p=0.017) in group D than in non-group D NTS gastroenteritis patients. A positive Widal test result was observed in 53.3% of group D and 6.7% of non-group D NTS cases (O-titer, p=0.030; H-titer, p=0.039). There were no differences in white blood cell counts, level of C-reactive protein and rate of antimicrobial resistance between group D and non-group D cases. Conclusion: The more severe clinical features such as headache, fever, and higher Widal titers were found to be indicative of group D NTS gastroenteritis. Additionally, group D NTS gastroenteritis was more commonly found in older patients. Therefore, old age, fever, headache, and a positive Widal test are more indicative of group D NTS than non-group D NTS gastroenteritis. Pathophysiological mechanisms may differ across serologic groups.

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